Support Document Approaches To Exposure Assessment
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Support Document Approaches To Exposure Assessment
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Author :
language : en
Publisher:
Release Date : 1980
Support Document Approaches To Exposure Assessment written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Health risk assessment categories.
Approaches To Exposure Assessment
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Author :
language : en
Publisher:
Release Date : 1980
Approaches To Exposure Assessment written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Chemicals categories.
Approaches To Exposure Assessment
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Author :
language : en
Publisher:
Release Date : 1980
Approaches To Exposure Assessment written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Chemicals categories.
Uncertainty And Data Quality In Exposure Assessment
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2008-12
Uncertainty And Data Quality In Exposure Assessment written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12 with History categories.
Assessment of human exposure to chemicals is a critical input to risk assessment and ultimately to decisions about control of chemicals. This two-part publication aims to improve the quality of information available to decision-makers and its communication. Part one sets out ten principles for characterizing and communicating uncertainty in exposure assessment. A tiered approach to the evaluation of uncertainties using both qualitative (simple) and quantitative (more complex) methods is described. Different sources of uncertainty are identified and guidance is provided on selecting the appropriate approach to uncertainty analysis as dictated by the objectives of the assessment and information needs of decision-makers and stakeholders. Part two addresses the quality of data used in exposure assessment and sets out four basic hallmarks of data quality - appropriateness accuracy integrity and transparency. These hallmarks provides a common vocabulary and set of qualitative criteria for use in the design evaluation and use of exposure assessments to support decisions. This publication is intended exposure assessors risk assessors and decision-makers.
Indexes
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Author : United States. Environmental Protection Agency
language : en
Publisher:
Release Date : 1983
Indexes written by United States. Environmental Protection Agency and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.
Human Exposure Assessment A Guide To Risk Ranking Risk Reduction And Research Planning
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Author :
language : en
Publisher: DIANE Publishing
Release Date :
Human Exposure Assessment A Guide To Risk Ranking Risk Reduction And Research Planning written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
A Framework To Guide Selection Of Chemical Alternatives
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2014-10-29
A Framework To Guide Selection Of Chemical Alternatives written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Science categories.
Historically, regulations governing chemical use have often focused on widely used chemicals and acute human health effects of exposure to them, as well as their potential to cause cancer and other adverse health effects. As scientific knowledge has expanded there has been an increased awareness of the mechanisms through which chemicals may exert harmful effects on human health, as well as their effects on other species and ecosystems. Identification of high-priority chemicals and other chemicals of concern has prompted a growing number of state and local governments, as well as major companies, to take steps beyond existing hazardous chemical federal legislation. Interest in approaches and policies that ensure that any new substances substituted for chemicals of concern are assessed as carefully and thoroughly as possible has also burgeoned. The overarching goal of these approaches is to avoid regrettable substitutions, which occur when a toxic chemical is replaced by another chemical that later proved unsuitable because of persistence, bioaccumulation, toxicity, or other concerns. Chemical alternative assessments are tools designed to facilitate consideration of these factors to assist stakeholders in identifying chemicals that may have the greatest likelihood of harm to human and ecological health, and to provide guidance on how the industry may develop and adopt safer alternatives. A Framework to Guide Selection of Chemical Alternatives develops and demonstrates a decision framework for evaluating potentially safer substitute chemicals as primarily determined by human health and ecological risks. This new framework is informed by previous efforts by regulatory agencies, academic institutions, and others to develop alternative assessment frameworks that could be operationalized. In addition to hazard assessments, the framework incorporates steps for life-cycle thinking - which considers possible impacts of a chemical at all stages including production, use, and disposal - as well as steps for performance and economic assessments. The report also highlights how modern information sources such as computational modeling can supplement traditional toxicology data in the assessment process. This new framework allows the evaluation of the full range of benefits and shortcomings of substitutes, and examination of tradeoffs between these risks and factors such as product functionality, product efficacy, process safety, and resource use. Through case studies, this report demonstrates how different users in contrasting decision contexts with diverse priorities can apply the framework. This report will be an essential resource to the chemical industry, environmentalists, ecologists, and state and local governments.
Methods Of Pesticide Exposure Assessment
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Author : Patricia B. Curry
language : en
Publisher: Springer
Release Date : 1995-09-30
Methods Of Pesticide Exposure Assessment written by Patricia B. Curry and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-30 with Medical categories.
This book is a summary of the presentations and discussions at the Workshop on Methods of Pesticide Exposure Assessment held in Ottawa, Canada, on October 5-8, 1993. The event was a joint effort of Health Canada and the North Atlantic Treaty Organisation and was officially supported by the United States Environmental Agency and the Organisation for Economic Co-operation and Development (OECD). The goal of the workshop was to examine current issues in the field of pesticide exposure assessment with the aim of reaching an internationally harmonized approach to methods of exposure assessment. With regulatory agencies of OECD Member countries moving towards the harmonization of data requirements, it was timely and beneficial to bring together international experts in the field of pesticide exposure assessment to discuss current issues. Approximately 60 delegates and 20 observers participated, including individuals from 15 different countries representing academia, government, industry and international organizations. A guidance document on methods of pesticide exposure assessment was presented as a means to achieving the goal of international for critique and discussion harmonization. After extensive discussion, the workshop delegates agreed in principle to procedures for revising the guidance document. Following revision and further review by a designated peer review group, the revised document will be submitted to the OECD for consideration as a draft OECD Guidance Document on pesticide exposure assessment methods. Both the revised and original documents are included in these proceedings.
Monthly Catalogue United States Public Documents
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Author :
language : en
Publisher:
Release Date : 1981
Monthly Catalogue United States Public Documents written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Government publications categories.
Applications Of Toxicogenomic Technologies To Predictive Toxicology And Risk Assessment
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2007-11-19
Applications Of Toxicogenomic Technologies To Predictive Toxicology And Risk Assessment written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-19 with Science categories.
The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.