A Framework To Guide Selection Of Chemical Alternatives
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A Framework To Guide Selection Of Chemical Alternatives
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2014-10-29
A Framework To Guide Selection Of Chemical Alternatives written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Science categories.
Historically, regulations governing chemical use have often focused on widely used chemicals and acute human health effects of exposure to them, as well as their potential to cause cancer and other adverse health effects. As scientific knowledge has expanded there has been an increased awareness of the mechanisms through which chemicals may exert harmful effects on human health, as well as their effects on other species and ecosystems. Identification of high-priority chemicals and other chemicals of concern has prompted a growing number of state and local governments, as well as major companies, to take steps beyond existing hazardous chemical federal legislation. Interest in approaches and policies that ensure that any new substances substituted for chemicals of concern are assessed as carefully and thoroughly as possible has also burgeoned. The overarching goal of these approaches is to avoid regrettable substitutions, which occur when a toxic chemical is replaced by another chemical that later proved unsuitable because of persistence, bioaccumulation, toxicity, or other concerns. Chemical alternative assessments are tools designed to facilitate consideration of these factors to assist stakeholders in identifying chemicals that may have the greatest likelihood of harm to human and ecological health, and to provide guidance on how the industry may develop and adopt safer alternatives. A Framework to Guide Selection of Chemical Alternatives develops and demonstrates a decision framework for evaluating potentially safer substitute chemicals as primarily determined by human health and ecological risks. This new framework is informed by previous efforts by regulatory agencies, academic institutions, and others to develop alternative assessment frameworks that could be operationalized. In addition to hazard assessments, the framework incorporates steps for life-cycle thinking - which considers possible impacts of a chemical at all stages including production, use, and disposal - as well as steps for performance and economic assessments. The report also highlights how modern information sources such as computational modeling can supplement traditional toxicology data in the assessment process. This new framework allows the evaluation of the full range of benefits and shortcomings of substitutes, and examination of tradeoffs between these risks and factors such as product functionality, product efficacy, process safety, and resource use. Through case studies, this report demonstrates how different users in contrasting decision contexts with diverse priorities can apply the framework. This report will be an essential resource to the chemical industry, environmentalists, ecologists, and state and local governments.
Chemical Alternatives Assessments
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Author :
language : en
Publisher: Royal Society of Chemistry
Release Date : 2013-04-30
Chemical Alternatives Assessments written by and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-30 with Technology & Engineering categories.
Chemicals are an essential part of everyday life and all too-often taken for granted, yet often portrayed negatively in the media. Concern over the deleterious effects of chemicals to the environment and human health have prompoted governments in the developed world to establish screening programmes such as REACH and HPV Challenge to identify chemicals presenting the greatest degree of risk to health and the environment. While such programmes identify chemicals with the greatest risk, there is no ranking system for alternative chemicals, which while being potentially less harmfull, still carry a degree of risk. This volume of the Issues in Environmental Science and Technology series investigates how the alternatives can be assessed and their risk determined. With contributions from experts across the globe, this volume addresses some of the key concepts behind risk assessment of alternative chemicals. Some of the current protocols adopted are discussed, and several chapters explore the topic in the context of industry, making this book essential reading for industrialists as well as academics, postgraduate students and policy makers.
Green Toxicology
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Author : Alexandra Maertens
language : en
Publisher: Royal Society of Chemistry
Release Date : 2022-02-01
Green Toxicology written by Alexandra Maertens and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-01 with Science categories.
Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.
A Class Approach To Hazard Assessment Of Organohalogen Flame Retardants
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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-07-19
A Class Approach To Hazard Assessment Of Organohalogen Flame Retardants written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-19 with Political Science categories.
In the 1970s, flame retardants began to be added to synthetic materials to meet strict flammability standards. Over the years, diverse flame retardants have been manufactured and used in various products. Some flame retardants have migrated out of the products, and this has led to widespread human exposure and environmental contamination. There also is mounting evidence that many flame retardants are associated with adverse human health effects. As a result, some flame retardants have been banned, restricted, or voluntarily phased out of production and use. This publication develops a scientifically based scoping plan to assess additive, nonpolymeric organohalogen flame retardants as a class for potential chronic health hazards under the Federal Hazardous Substances Act, including cancer, birth defects, and gene mutations.
Sustainability In The Design Synthesis And Analysis Of Chemical Engineering Processes
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Author : Gerardo Ruiz Mercado
language : en
Publisher: Butterworth-Heinemann
Release Date : 2016-07-29
Sustainability In The Design Synthesis And Analysis Of Chemical Engineering Processes written by Gerardo Ruiz Mercado and has been published by Butterworth-Heinemann this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-29 with Technology & Engineering categories.
Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz-Mercado and Cabezas have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia. This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabezas’ book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes and products with sustainability in mind; from conceptual design to life cycle assessment Avoid retro fitting costs by planning for sustainability concerns at the start of the design process Link sustainability to the chemical engineering fundamentals
Cleaner Technologies Substitutes Assessment
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Author : Lori E. Kincaid
language : en
Publisher:
Release Date : 1997
Cleaner Technologies Substitutes Assessment written by Lori E. Kincaid and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Nature categories.
The Use And Storage Of Methyl Isocyanate Mic At Bayer Cropscience
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-08-31
The Use And Storage Of Methyl Isocyanate Mic At Bayer Cropscience written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-31 with Science categories.
The use of hazardous chemicals such as methyl isocyanate can be a significant concern to the residents of communities adjacent to chemical facilities, but is often an integral part of the chemical manufacturing process. In order to ensure that chemical manufacturing takes place in a manner that is safe for workers, members of the local community, and the environment, the philosophy of inherently safer processing can be used to identify opportunities to eliminate or reduce the hazards associated with chemical processing. However, the concepts of inherently safer process analysis have not yet been adopted in all chemical manufacturing plants. The Use and Storage of Methyl Isocyanate (MIC) at Bayer CropScience presents a possible framework to help plant managers choose between alternative processing options-considering factors such as environmental impact and product yield as well as safety- to develop a chemical manufacturing system. In 2008, an explosion at the Bayer CropScience chemical production plant in Institute, West Virginia, resulted in the deaths of two employees, a fire within the production unit, and extensive damage to nearby structures. The accident drew renewed attention to the fact that the Bayer facility manufactured and stores methyl isocyanate, or MIC - a volatile, highly toxic chemical used in the production of carbamate pesticides and the agent responsible for thousands of death in Bhopal, India, in 1984. In the Institute accident, debris from the blast hit the shield surrounding a MIC storage tank, and although the container was not damaged, an investigation by the U.S. Chemical Safety and Hazard Investigation Board found that the debris could have struck a relief valve vent pipe and cause the release of MIC to the atmosphere. The Board's investigation also highlighted a number of weaknesses in the Bayer facility's emergency response systems. In light of these concerns, the Board requested the National Research Council convene a committee of independent experts to write a report that examines the use and storage of MIC at the Bayer facility. The Use and Storage of Methyl Isocyanate (MIC) at Bayer CropScience also evaluates the analyses on alternative production methods for MIC and carbamate pesticides preformed by Bayer and the previous owners of the facility.
Toxicity Testing In The 21st Century
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2007-11-05
Toxicity Testing In The 21st Century written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-05 with Nature categories.
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.
Structured Decision Making
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Author : Robin Gregory
language : en
Publisher: John Wiley & Sons
Release Date : 2012-03-19
Structured Decision Making written by Robin Gregory and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-19 with Mathematics categories.
This book outlines the creative process of making environmental management decisions using the approach called Structured Decision Making. It is a short introductory guide to this popular form of decision making and is aimed at environmental managers and scientists. This is a distinctly pragmatic label given to ways for helping individuals and groups think through tough multidimensional choices characterized by uncertain science, diverse stakeholders, and difficult tradeoffs. This is the everyday reality of environmental management, yet many important decisions currently are made on an ad hoc basis that lacks a solid value-based foundation, ignores key information, and results in selection of an inferior alternative. Making progress – in a way that is rigorous, inclusive, defensible and transparent – requires combining analytical methods drawn from the decision sciences and applied ecology with deliberative insights from cognitive psychology, facilitation and negotiation. The authors review key methods and discuss case-study examples based in their experiences in communities, boardrooms, and stakeholder meetings. The goal of this book is to lay out a compelling guide that will change how you think about making environmental decisions. Visit www.wiley.com/go/gregory/ to access the figures and tables from the book.
Guidelines For Drinking Water Quality
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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 1993
Guidelines For Drinking Water Quality written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
This volume describes the methods used in the surveillance of drinking water quality in the light of the special problems of small-community supplies, particularly in developing countries, and outlines the strategies necessary to ensure that surveillance is effective.