Supramolecular Structure And Function Six
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Structure And Function Of The Extracellular Matrix
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Author : Bela Suki
language : en
Publisher: Academic Press
Release Date : 2021-11-27
Structure And Function Of The Extracellular Matrix written by Bela Suki and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-27 with Technology & Engineering categories.
Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki's book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book. - Examines the evolutionary origins and consequences of the extracellular matrix - Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system - Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning - Provides an introduction to the properties and organization of the extracellular matrix components
Polyphosphazenes For Biomedical Applications
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Author : K. A. Andrianov
language : en
Publisher: John Wiley & Sons
Release Date : 2009-07-28
Polyphosphazenes For Biomedical Applications written by K. A. Andrianov and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-28 with Science categories.
Brings together, analyzes, and contextualizes the latest findings and practical applications Polyphosphazenes, an emerging class of polymers, include macromolecules, which have been proven to be biocompatible, biodegradable, and bioactive. Their unprecedented structural diversity and unique properties make them suitable as vaccine adjuvants, microencapsulating agents, biodegradable materials, scaffolds for tissue engineering, biocompatible coatings, and carriers for gene delivery. Polyphosphazenes for Biomedical Applications offers a thorough review of polyphosphazene research findings in the life sciences, chemistry, and chemical engineering. It emphasizes biomedical applications as well as recent advances in polyphosphazene development such as high-throughput discovery and the latest controlled methods of synthesis. The book brings together, analyzes, and contextualizes a wealth of knowledge that previously could only be found scattered throughout the scientific literature. Following two introductory chapters, the book reviews: Vaccine delivery and immunomodulation Biomaterials Drug delivery systems Biodetection Well-defined polyphosphazenes: synthetic aspects and novel molecular architectures All the chapters have been written by leading researchers in the field. Editor Alexander Andrianov, who has led the effort to commercialize polyphosphazenes for biomedical applications, has carefully reviewed and edited all chapters to ensure readability, accuracy, and thoroughness. Polyphosphazenes for Biomedical Applications is not only intended for researchers working in polyphosphazene chemistry, but also for all researchers seeking solutions to problems arising in the areas of biomaterials, drug delivery systems, and controlled release formulations.
Supramolecular Protein Chemistry
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Author : Peter B Crowley
language : en
Publisher: Royal Society of Chemistry
Release Date : 2020-12-09
Supramolecular Protein Chemistry written by Peter B Crowley and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-12-09 with Science categories.
Building on decades of “host-guest” research, recent years have seen a surge of activity in water-soluble supramolecular receptors for protein recognition and assembly. Progress has been particularly rich in the area of calixarenes, cucurbiturils and molecular tweezers. Emerging applications include controlled protein assembly in solution, crystal engineering, supramolecular control of catalysis (both in vitro and in vivo), as well as novel mechanisms of protein-interaction inhibition with relevance to amyloids and disease. One challenge at the interface of supramolecular chemistry and protein science is to increase interaction and collaboration between chemists and biochemists/structural biologists.This book addresses the exciting interface of supramolecular chemistry and protein science. Chapters cover supramolecular approaches to protein recognition, assembly and regulation. Principles outlined will highlight the opportunities that are readily accessible to collaborating chemists and biochemists, enriching the breadth and scope of this multidisciplinary field. Supramolecular Protein Chemistry will be of particular interest to graduate students and researchers working in supramolecular chemistry, protein science, self-assembly, biomaterials, biomedicine and biotechnology.
Heparanase
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Author : Israel Vlodavsky
language : en
Publisher: Springer Nature
Release Date : 2020-04-09
Heparanase written by Israel Vlodavsky and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-09 with Medical categories.
Written by internationally recognized leaders in Heparanase biology, the book’s eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.
Cell Biology A Comprehensive Treatise V4
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Author : David M. Prescott
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Cell Biology A Comprehensive Treatise V4 written by David M. Prescott and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Cell Biology, A Comprehensive Treatise, Volume 4: Gene Expression: Translation and the Behavior of Proteins discusses the translation of genetic information into proteins. It also explains the activities and behaviors of proteins, which is the final stage of gene expression. This book opens with a discussion of the components and mechanism of the translational machinery – their structures, biogenesis, and cellular levels. It then explains the protein synthesis, wherein each chapter focuses on one aspect of the detailed process. Other topics covered in this book are the structure and function of cytoplasmic ribonucleoprotein complexes and the proteolytic cleavage in the posttranslational processing of proteins. This text also covers the regulation of enzyme activity and the movement of material between nucleus and cytoplasm. The last three chapters are more in-depth discussions on protein synthesis, intracellular transport, regulation, and secretion. As with the other volumes of this book series, readers will definitely benefit from the vast information provided in this book regarding protein, its activities, behaviors, and synthesis.
Block Copolymers In Nanoscience
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Author : Massimo Lazzari
language : en
Publisher: John Wiley & Sons
Release Date : 2007-06-27
Block Copolymers In Nanoscience written by Massimo Lazzari and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-27 with Technology & Engineering categories.
This first book to take a detailed look at one of the key focal points where nanotechnology and polymers meet provides both an introductory view for beginners as well as in-depth knowledge for specialists in the various research areas involved. It investigates all types of application for block copolymers: as tools for fabricating other nanomaterials, as structural components in hybrid materials and nanocomposites, and as functional materials. The multidisciplinary approach covers all stages from chemical synthesis and characterization, presenting applications from physics and chemistry to biology and medicine, such as micro- and nanolithography, membranes, optical labeling, drug delivery, as well as sensory and analytical uses.
Antimicrobial Peptides Molecular Design Structure Function Relationship And Biosynthesis Optimization
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Author : Jianhua Wang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-04
Antimicrobial Peptides Molecular Design Structure Function Relationship And Biosynthesis Optimization written by Jianhua Wang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-04 with Science categories.
Advanced Self Assembled Materials With Programmable Functions
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Author : Huacheng Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-05-04
Advanced Self Assembled Materials With Programmable Functions written by Huacheng Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-04 with Science categories.
Guide To Programs
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Author : National Science Foundation (U.S.)
language : en
Publisher:
Release Date : 1996
Guide To Programs written by National Science Foundation (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Federal aid to research categories.
Soft Matter Characterization
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Author : Redouane Borsali
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-07-28
Soft Matter Characterization written by Redouane Borsali and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-28 with Science categories.
This 2-volume set includes extensive discussions of scattering techniques (light, neutron and X-ray) and related fluctuation and grating techniques that are at the forefront of this field. Most of the scattering techniques are Fourier space techniques. Recent advances have seen the development of powerful direct imaging methods such as atomic force microscopy and scanning probe microscopy. In addition, techniques that can be used to manipulate soft matter on the nanometer scale are also in rapid development. These include the scanning probe microscopy technique mentioned above as well as optical and magnetic tweezers.