Synapse Development Methods And Protocols
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Synapse Development Methods And Protocols
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Author : Alexandros Poulopoulos
language : en
Publisher: Methods in Molecular Biology
Release Date : 2018-12-24
Synapse Development Methods And Protocols written by Alexandros Poulopoulos and has been published by Methods in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-24 with Medical categories.
Neural Development
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Author : Renping Zhou
language : en
Publisher: Anchor Books
Release Date : 2013
Neural Development written by Renping Zhou and has been published by Anchor Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Biomedicine categories.
Understanding the molecular and cellular mechanisms underlying the development of specific neural circuits is not just an intellectual curiosity but also central to our ability to develop therapeutic approaches to repair damaged pathways in the future. In Neural Development: Methods and Protocols, experts in the field contribute commonly used protocols to facilitate future research in developmental neuroscience. Split into four convenient sections, this detailed volume covers techniques of culturing neurons and glia as well as their growth and differentiation, methods of gene delivery and down regulation, protocols for analyzing axon growth and guidance plus synapse formation, and, finally, basic methods to analyze brain morphology and axon pathways in developing animals. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and accessible, Neural Development: Methods and Protocols provides key guidance for students and postdoctoral fellows new to developmental neurobiology.
Cerebral Cortex Development
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Author : Koh-ichi Nagata
language : en
Publisher: Springer Nature
Release Date :
Cerebral Cortex Development written by Koh-ichi Nagata and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Neurotrophic Factors
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Author : Stephen D Skaper
language : en
Publisher: Humana Press
Release Date : 2012-02-25
Neurotrophic Factors written by Stephen D Skaper and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-25 with Medical categories.
Nervous system development evolves from the well-orchestrated processes of neural induction, cell proliferation, differentiation, cell migration, survival, and synapse formation. Among these environmental cues, neurotrophic factors are secreted proteins that promote neurite outgrowth, neuronal cell differentiation and survival both in vivo and in vitro. Nerve growth factor (NGF) is the founding and best characterized member of the neurotrophin family of neurotrophic polypeptides. Neurotrophic Factors: Methods and Protocols presents a selection of protocols and procedures which make use of cellular, tissue, and whole animal models which can be applied to the investigation of neurotrophic factors and other agents impacting on these systems. Chapters cover a wide-range of topics such as dealing with the culture of neurons and glia from the central and peripheral nervous systems, neuron-glia co-culture models, and cell-based assays for the evaluation of neuroprotective molecules, as well as assays which can be applied to the study of agents with neuroregenerative potential. Protocols describing viral- and nanoparticle-based delivery methods to neural cells are also presented, following by chapters dealing with organotypic slice culture protocols. Lastly, several chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neurotrophic Factors: Methods and Protocols seeks to serve both professionals and novices alike with its well-honed methodologies in an effort to further our knowledge of what has been described as the last frontier of science.
Synaptic Vesicles
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Author : Jana Dahlmanns
language : en
Publisher:
Release Date : 2022
Synaptic Vesicles written by Jana Dahlmanns and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Synaptic vesicles categories.
This book provides protocols on the preparation of synaptic vesicles from different model systems and provides instructions for functional investigations of their transport and formation, scaffolding, filling and priming, release, recycling, and degradation. Chapters guide readers through computational approaches, simulating different aspects of synaptic vesicle anatomy and function. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Synaptic Vesicles: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.
The Immune Synapse
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Author : Cosima T. Baldari
language : en
Publisher: Springer Nature
Release Date : 2023-04-27
The Immune Synapse written by Cosima T. Baldari and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-27 with Science categories.
This new collection features the most up-to-date essential protocols that are currently being used to study the immune synapse. Beginning with methods for making biophysical measurements, the volume continues by covering the cell biology of synapses, methods for advanced substrate engineering, mechanobiology topics, new technologies to describe and manipulate synaptic components, as well as methods related to sites of action and immunotherapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and fully updated, The Immune Synapse: Methods and Protocols, Second Edition serves as an ideal practical guide for researchers working in this dynamic field. Chapters 5, 11, 18, 27, 30, and 32 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Synapse Development And Maturation
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Author : Pasko Rakic
language : en
Publisher: Academic Press
Release Date : 2020-05-29
Synapse Development And Maturation written by Pasko Rakic and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-29 with Psychology categories.
Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity
Methods And Procedures For The Verification And Validation Of Artificial Neural Networks
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Author : Brian J. Taylor
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-20
Methods And Procedures For The Verification And Validation Of Artificial Neural Networks written by Brian J. Taylor and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with Computers categories.
Neural networks are members of a class of software that have the potential to enable intelligent computational systems capable of simulating characteristics of biological thinking and learning. Currently no standards exist to verify and validate neural network-based systems. NASA Independent Verification and Validation Facility has contracted the Institute for Scientific Research, Inc. to perform research on this topic and develop a comprehensive guide to performing V&V on adaptive systems, with emphasis on neural networks used in safety-critical or mission-critical applications. Methods and Procedures for the Verification and Validation of Artificial Neural Networks is the culmination of the first steps in that research. This volume introduces some of the more promising methods and techniques used for the verification and validation (V&V) of neural networks and adaptive systems. A comprehensive guide to performing V&V on neural network systems, aligned with the IEEE Standard for Software Verification and Validation, will follow this book.
Neurobiology
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Author : Sebastian Dworkin
language : en
Publisher: Springer Nature
Release Date : 2023-12-09
Neurobiology written by Sebastian Dworkin and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-09 with Medical categories.
This volume will serve as a guide for students in the field of neurobiology, and be a bridge between basic science researchers, doctors, and surgeons in clinical practice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Neurobiology: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Molecular Cellular And Model Organism Approaches For Understanding The Basis Of Neurological Disease
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Author : Robert J. Harvey
language : en
Publisher: Frontiers Media SA
Release Date : 2017-07-05
Molecular Cellular And Model Organism Approaches For Understanding The Basis Of Neurological Disease written by Robert J. Harvey and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-05 with Electronic book categories.
The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.