Neurotrophic Factors
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Neurotrophic Factors
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Author : Sandra E. Loughlin
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Neurotrophic Factors written by Sandra E. Loughlin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
This volume clearly synthesizes current information on defined neurotrophic factors, emphasizing their localization and molecular/cellular function in the central nervous system. Brain development and aging, neurodegenerative disorders, plasticity, and memory all are closely examined within the context of this rapidly expanding field. Researchers in neurobiology, cell biology, and molecular biology will find Neurotrophic Factors an invaluable reference for their research libraries. Offers the most up-do-date synthesis of concepts on neurotrophic factors in the nervous system Integrates molecular, cellular, and neuroanatomical concepts of neurotrophic factor function Includes special chapters on primary, secondary, and tertiary messenger systems Examines brain development, differentiation, neurodegenerative disorders, and adult plasticity
Neurotrophic Factors
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Author : Patrick Aebischer
language : en
Publisher: Springer
Release Date : 1998-10
Neurotrophic Factors written by Patrick Aebischer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10 with Medical categories.
With contributions of numerous experts.
Life And Death In The Nervous System
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Author : C. F. Ibanez
language : en
Publisher: Elsevier Health Sciences
Release Date : 1995-12-22
Life And Death In The Nervous System written by C. F. Ibanez and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-22 with Medical categories.
Life and Death in the Nervous System
Neurotrophic Factors
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Author : Stephen D Skaper
language : en
Publisher: Humana Press
Release Date : 2012-02-25
Neurotrophic Factors written by Stephen D Skaper and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-25 with Medical categories.
Nervous system development evolves from the well-orchestrated processes of neural induction, cell proliferation, differentiation, cell migration, survival, and synapse formation. Among these environmental cues, neurotrophic factors are secreted proteins that promote neurite outgrowth, neuronal cell differentiation and survival both in vivo and in vitro. Nerve growth factor (NGF) is the founding and best characterized member of the neurotrophin family of neurotrophic polypeptides. Neurotrophic Factors: Methods and Protocols presents a selection of protocols and procedures which make use of cellular, tissue, and whole animal models which can be applied to the investigation of neurotrophic factors and other agents impacting on these systems. Chapters cover a wide-range of topics such as dealing with the culture of neurons and glia from the central and peripheral nervous systems, neuron-glia co-culture models, and cell-based assays for the evaluation of neuroprotective molecules, as well as assays which can be applied to the study of agents with neuroregenerative potential. Protocols describing viral- and nanoparticle-based delivery methods to neural cells are also presented, following by chapters dealing with organotypic slice culture protocols. Lastly, several chapters are dedicated to in vivo lesion models of relevance to nervous system pathology, which can be applied to the investigation of neurotrophic factors and peptides. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neurotrophic Factors: Methods and Protocols seeks to serve both professionals and novices alike with its well-honed methodologies in an effort to further our knowledge of what has been described as the last frontier of science.
Clinical Applications Of Neurotrophic Factors
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Author : Stuart C. Apfel
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1997
Clinical Applications Of Neurotrophic Factors written by Stuart C. Apfel and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Growth factors categories.
Neurotrophic Factors
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Author : Franz Hefti
language : en
Publisher:
Release Date : 1998-10-01
Neurotrophic Factors written by Franz Hefti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-10-01 with categories.
This volume provides the first comprehensive overview of a novel field of neuropharmacology. Neurotrophic factors are currently in clinical trials and there is a broad research effort which aims at alternative administration strategies and at replacing them with small molecule mimetics. The field represents a unique and novel approach to the treatment of neurodegenerative diseases.
Neurotrophin Protocols
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Author : Robert A. Rush
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-03
Neurotrophin Protocols written by Robert A. Rush and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-03 with Medical categories.
The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this activity. Nevertheless, this area of research has often struggled as a result of techniques that were either inadequate or just emerging from other research fields and disciplines. Neurotrophin Protocols has brought together many leaders in the neurotrophin field who detail their special expertise in a wide variety of techniques. Though most procedures are valid across many diff- ent fields of research, some of those described here have been developed to address particular issues within the neurotrophic factor field. The protocols cover a broad range of biochemical, histological, and biological techniques that are often required by the modern laboratory. However, all have been written with sufficient detail to allow any laboratory to achieve proficiency without need of reference to other texts. Neurotrophin Protocols is divided into four sections dealing with p- tein, RNA, recombinant, and in vivo techniques. Protein techniques have in general been less successfully employed than those dealing with RNA or DNA. However, procedures that achieve localization and quantification of the neurotrophins are now being used more extensively. Their inclusion here should assist further studies at the protein level. Transgenic cell lines and animals are commonplace in the scientific research literature, but their inc- sion in several chapters in this book provide some novel uses that are not readily available elsewhere.
Evolution Of Neurotrophic Factors
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Author : Christopher S. von Bartheld
language : en
Publisher:
Release Date : 2006
Evolution Of Neurotrophic Factors written by Christopher S. von Bartheld and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with categories.
This special issue reviews current knowledge about the evolution of several key neurotrophic factors, including the neurotrophins and the GDNF family, as well as EGF receptor ligands. Leading researchers from six countries provide concise updates on the origin and evolution of neurotrophic factors and their receptors. The authors trace major developments in the structure and function of neurotrophic factors during the course of 800 million years of evolution, from prechordates to mammals. This collection of papers presents the first systematic and comprehensive survey of the origins and diversification of neurotrophic factors and their essential roles not only in ontogeny but also in phylogeny of the brain and behavior in both invertebrates and vertebrates. The contributions help achieve a true understanding of neurotrophic factors and their roles in brain evolution. This issue is a valuable source of information for developmental biologists, comparative and evolutionary biologists, molecular biologists, geneticists, and researchers interested in signaling systems, trophic factor biology, neuropharmacology, brain plasticity, and brain repair.
Exploring The Clinical Implications Of Brain Derived Neurotrophic Factor Bdnf
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Author : Dr.Hakim Saboowala
language : en
Publisher: Dr.Hakim Saboowala
Release Date : 2022-01-06
Exploring The Clinical Implications Of Brain Derived Neurotrophic Factor Bdnf written by Dr.Hakim Saboowala and has been published by Dr.Hakim Saboowala this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-06 with Medical categories.
Exploring the Clinical Implications of Brain-derived Neurotrophic Factor (BDNF). Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors that support: · Differentiation, · Maturation, and · Survival of Neurons in the Nervous System and shows a Neuroprotective effect under adverse conditions, such as: · Glutamatergic stimulation, · Cerebral ischemia, · Hypoglycemia, and · Neurotoxicity. Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival and growth, serves as a neurotransmitter modulator, and participates in neuronal plasticity, which is essential for learning and memory. BDNF and insulin-like growth factor-1 have similar downstream signalling mechanisms incorporating both p-CAMK and MAPK that increase the expression of pro-survival genes. Brain-derived neurotrophic factor regulates glucose and energy metabolism and prevents exhaustion of β cells. Decreased levels of BDNF are associated with neurodegenerative diseases with neuronal loss. Thus, an attempt has been made in this E-Booklet to describe everything about BDNF elaborately along with several relevant ILLUSRATIONS for better understanding! …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)
Glial Cell Line Derived Neurotrophic Factors Advances In Research And Application 2012 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-12-26
Glial Cell Line Derived Neurotrophic Factors Advances In Research And Application 2012 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-26 with Medical categories.
Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Glial Cell Line-Derived Neurotrophic Fa in a concise format. The editors have built Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Glial Cell Line-Derived Neurotrophic Fa in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Glial Cell Line-Derived Neurotrophic Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.