Synthetic Peptides
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Synthetic Peptides
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Author : Gregory Grant
language : en
Publisher: Oxford University Press
Release Date : 2002-04-04
Synthetic Peptides written by Gregory Grant and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-04-04 with Science categories.
The first synthetic peptides were produced a century ago. In the ensuing period, they have developed as valuable research tools that are readily available to all researchers. However, since most researchers do not make their own peptides, they are often unfamiliar with not only the synthetic chemistry but also with important and useful aspects of design, analysis, handling, and applications. This volume is the second edition of a volume that was first published 10 years ago. It is written by experts in the field who provide detailed descriptions as well as practical advice for producing and using synthetic peptides. The various chapters cover peptide design considerations, the synthetic chemistry, the evaluation of the synthetic product, and the modern applications of synthetic peptides. This includes the basic principles of peptide structure, analysis and chain assembly as well as the latest in selective disulfide bond formation, new strategies for the production of large peptides, and sequencing peptides by mass spectrometry. This book was designed with the intent of providing useful information both for the novices to the field as well as more seasoned practitioners. Its contents will help prevent problems commonly encountered and allow scientists to optimize their use of synthetic peptides.
Synthetic Peptides
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Author : Gregory A. Grant
language : en
Publisher: W H Freeman & Company
Release Date : 1992
Synthetic Peptides written by Gregory A. Grant and has been published by W H Freeman & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Science categories.
Contemporary solid-phase peptide synthesis is a streamlined, automated technology and its products are more readily available to a larger group of researchers than ever before. But because many researchers rely on contract services to obtain their peptides, they are often not familiar with the "tricks of the trade" in artificial peptide design, manufacturing, and handling. This practical guide to the new peptide synthesis helps you to use artificial peptides more effectively, devise efficient experiments and avoid common pitfalls. The appendix lists sources offering custom peptide synthesis or other analytical services. Synthetic Peptides is the second volume in the UWBC Biotechnical Resource Series with Dr. Richard R. Burgess, Director of the University of Wisconsin Biotechnology Center, as Series Editor. The series is dedicated to providing practical guidance to researchers exploring new technologies and services.
Folded Synthetic Peptides For Biomedical Applications
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Author : Alessandro Contini
language : en
Publisher: Frontiers Media SA
Release Date : 2019-09-26
Folded Synthetic Peptides For Biomedical Applications written by Alessandro Contini and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-26 with categories.
Folded peptides - and peptide motifs within proteins - are abundant in living organisms, where they are essential for the biological activities of the peptides and proteins. During the past decades, much research has been dedicated to understanding the rules that govern peptide folding. Simultaneously, a range of strategies have been established for the conformational stabilization of bioactive peptides, as well as for the de novo design of peptides with defined secondary structures. These methods are either based on the chemical modification of the peptide backbone, such as cyclization and stapled peptides, or on the use of a range of non-proteinogenic amino acids that, in a defined sequential arrangement, induce secondary structures peptides. Such building blocks include D- and other non-proteinogenic amino acids, as well as beta- and gamma-amino acids. This Research Topic comprises a collection of papers by an international group of 77 scientists with a background in synthetic, analytical, computational and medicinal chemistry, as well as in biochemistry and pharmacology. Their research is presented here in a total of 11 papers (8 original research reports and 3 reviews), covering diverse aspects of folded synthetic peptides. These studies include the preparation and characterization of new peptide monomers with interesting folding properties, the synthesis and conformational analysis of non-natural peptides, as well as the use of folded peptidomimetics as molecular switches. Additionally, a range of biomedical applications, such as antimicrobial, anti-inflammatory, antiangiogenic and immune-stimulating activities, are also reported. We hope this eBook will be a source of inspiration and knowledge for scientist in various disciplines related to folded peptides and their many applications, as well as for those who want to learn more about this fascinating field of research.
Synthetic Peptides As Antigens
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Author : Ruth Porter
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Synthetic Peptides As Antigens written by Ruth Porter and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Medical categories.
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Synthetic Peptides
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Author : George R. Pettit
language : en
Publisher: Elsevier
Release Date : 2014-05-10
Synthetic Peptides written by George R. Pettit and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
Synthetic Peptides discusses racemization, protecting group techniques, peptide bond-forming methodology, amino acids, and dipeptide syntheses. The book explains solid phase synthesis methods, cyclopeptides, nucleopeptides, chromopeptides of the actinomycin D type, and cites examples of syntheses of peptides of different sizes. The text describes tripeptides, tetrapeptides, pentapeptides, hexapeptides, and also undecapeptides to nonadecapeptides. Riniker and colleagues explain the revised structures (for the human and porcine hormone, Asn for Asp at position 25 and Glu for Gin at position 30) for the 39-unit adrenocorticotropic hormone. A synthesis of the 32-unit human calcitonin M is associated with the fragment condensation approach to complex peptides. The book also reviews cyclodepsipeptide valinomycin based on the possible transport of a potassium ion through biological membranes by this substance and the synthesis of a D-Pro analog. The text describes the cyclic decapeptide antibiotic gramicidin S, belonging to a family of similar substances isolated from Bacillus brevi, that can treat certain eye-threatening infections. The book can prove beneficial for biochemists, micro-biologists, cellular investigators, and researchers involved in physiology, oncology or therapeutics.
Peptide Synthesis
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Author : Jaya Varkey
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-18
Peptide Synthesis written by Jaya Varkey and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-18 with Science categories.
Peptide synthesis includes an array of techniques and procedures that enable the preparation of materials ranging from small peptides to large proteins. Many synthetic peptides have commercial and pharmaceutical applications, however, the synthesis of these peptides is a difficult task. This book addresses the common problems relating to the synthesis and applications of synthetic peptides. It discusses novel methods for the efficient synthesis of long chain and difficult peptide sequences and presents detailed analysis of various aspects of solid phase peptide synthesis. It also includes a section on antimicrobial peptides.
Synthetic Peptides In Biology And Medicine
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Author : Kari Alitalo
language : en
Publisher: Elsevier Science & Technology
Release Date : 1985
Synthetic Peptides In Biology And Medicine written by Kari Alitalo and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Science categories.
Synthetic Peptides As Antigens
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Author : S. Muller
language : en
Publisher: Elsevier Science
Release Date : 1999-11-19
Synthetic Peptides As Antigens written by S. Muller and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-19 with Medical categories.
This newest edition to the Laboratory Techniques Series gives current state of the art use of synthetic peptides in molecular biology and practical protocols on how to conjugate peptides, immunize animals with peptides and monitor immune responses to peptides in vitro. It gives background information on antigenic specificity, prediction of antigenic sites in proteins and applications of peptides in immunology and virology, as probes in diagnosis and as vaccines. The book also describes antigenicity of proteins and methods to localize antigenic sites as well as methods for predicting epitoxes, and gives detailed protocols for peptide-carrier conjugation, immunization with peptides, and peptide immunoassays. The volume also describes typical use of antipeptide antibodies in molecular and cellular biology as well as the use of peptides in the diagnosis of viral infections and autoimmune diseases, and the use of peptides as potential synthetic vaccines. An excellent edition to an excellent series, available in hardbound and paperback.
Synthetic Peptides
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Author : George R. Pettit
language : en
Publisher:
Release Date : 1970
Synthetic Peptides written by George R. Pettit and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Peptides categories.
Synthetic Polypeptides As Antigens
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Author : J.P. Briand
language : en
Publisher: Elsevier
Release Date : 1988-11-01
Synthetic Polypeptides As Antigens written by J.P. Briand and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-11-01 with Medical categories.
Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays. This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic sites. Recent advances in the detection of gene products with antipeptide antibodies, and the still controversial use of synthetic peptides as vaccines are also described. The book provides: - detailed descriptions of procedures - extensive bibliography - detailed analysis of the structural basis of antigenicity in proteins Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology. Those using synthetic peptides as immunological probes will find this a most useful book, as will those wishing to overcome the difficulties of achieving antigenic mimicry by synthesis.