T Cell Memory
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Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Persistent Viral Infections
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Author : R. Ahmed
language : en
Publisher: Wiley-Blackwell
Release Date : 1999
Persistent Viral Infections written by R. Ahmed and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.
T Cell Memory
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Author : David Masopust
language : en
Publisher:
Release Date : 2021
T Cell Memory written by David Masopust and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.
T cells are a major component of adaptive immunity, differentiating to form distinct subsets that directly attack pathogens, promote the activity of antibody-producing cells, and regulate other components of the immune system. This volume discusses the roles of these different subsets and how they are generated. Topics covered in this essential volume include: - Memory T-cell heterogeneity and classification: How should we name our T-cells? - Memory T-cell differentiation models - Tissue memory - Memory T-cell homeostasis and durability
Memory T Cells
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Author : Maurizio Zanetti
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-11
Memory T Cells written by Maurizio Zanetti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-11 with Medical categories.
Immunological memory has fascinated microbiologists and immunologists for decades as one of the new frontiers to conquer to better understand the response to pathogens, cancer and vaccination. Over the past decade, attention has turned to the intrinsic properties of the memory T cells themselves, as it has become clear that the eradication of both infected cells and tumors requires T cells. This book is an attempt to capture the wave of discoveries associated with these recent studies. Its chapters represent a wide collection of topics related to memory T cells by laboratories that have invested their skills and knowledge to understand the biology and the principles upon which memory T cells are generated, maintained and expanded upon re-encounter with antigen. Ultimately, these studies are all aimed at a better understanding of the function of memory T cells in protection against disease.
The Vaccine Book
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Author : Barry R. Bloom
language : en
Publisher: Academic Press
Release Date : 2016-06-23
The Vaccine Book written by Barry R. Bloom and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-23 with Science categories.
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy
Differentiation Tissue Adaptation And Function Of Memory T Cells
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Author : Weiguo Cui
language : en
Publisher: Frontiers Media SA
Release Date : 2020-06-16
Differentiation Tissue Adaptation And Function Of Memory T Cells written by Weiguo Cui and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-16 with categories.
Upon antigen encounter, naïve T cells differentiate into (i) effectors that combat infected or malignant cells, and at later time points, into (ii) memory cells that provide long-lasting immunity. This differentiation process allows some T cells to leave the confines of secondary lymphoid organs and to enter peripheral tissues in search of pathogens or tumor cells. These different environments pose specific challenges for effector and memory T cells to maintain homeostasis. T cells directed into the lungs are likely to encounter higher levels of oxygen, but lower amounts of nutrients than those directed into the intestinal epithelium. In addition to oxygen tension and nutrient concentrations, other key factors, such as the commensal flora and stromal components, create unique conditions that require tissue-specific adaptations of T cells. These steady state conditions can dramatically change during infection when inflammatory mediators and T cell growth factors are released, requiring the immediate response of T cells. The gradual changes imposed by growing tumors can also be challenging for T cells due to competition with rapidly cycling tumor cells that deplete essential resources of oxygen and glucose. The strategies that T cells employ to respond to the diverse cues from their surroundings are the focus of current research. It appears that next to circulating memory T cells that are confined to the circulation and those that survey all of the peripheral tissues, dedicated populations of resident memory T cells exist that can optimally adapt to the local circumstances within each tissue. Restrictions on the metabolic requirements of T cells residing in tumor tissue have been found to directly impact on effector functions such as cytokine production. The fundamental principles of how the machinery of T cells can translate local cues into tissue-specific differentiation processes are fascinating and warrant further investigation.
Resident Memory T Cells Guardians Of The Balance Of Local Immunity And Pathology
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Author : Nick P. Goplen
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-25
Resident Memory T Cells Guardians Of The Balance Of Local Immunity And Pathology written by Nick P. Goplen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-25 with Medical categories.
Human Microbiota In Health And Disease
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Author : Bryan Tungland
language : en
Publisher: Academic Press
Release Date : 2018-05-25
Human Microbiota In Health And Disease written by Bryan Tungland and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-25 with Science categories.
Human Gut Microbiota in Health and Disease: From Pathogenesis to Therapy is a comprehensive discussion on all the aspects associated with the early colonization of gut microbiota, its development and maintenance, and its symbiotic relationship with the host in promoting health. Chapters illustrate the complex mechanisms and metabolic signaling pathways related to how the gut microbiota maintain proper regulation of glucose, lipid and energy homeostasis and immune response, all while mediating inflammatory processes involved in the etiology of many chronic disease conditions. With today's common use of pharmaceutical medicine in treating symptoms and frequent overuse of antibiotics in chronic disease within mainstream medical practice, our understanding of the etiological mechanisms of dysbiosis-induced chronic disease and natural approaches to prevention and potential cures for these diseases is of vital importance to overall human health. Details the complex relationship between human microbiota in the gut, oral cavity and skin as well as their colonization, development and impact of factors that influence the relationship Illustrates the mechanisms associated with dysbiosis-associated inflammation and its role in the onset and progression in chronic disease Provides the primary mechanisms and comprehensive scientific evidence for the use of dietary modification and pro- and prebiotics in preventing chronic disease
Handbook On Immunosenescence
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Author : Tamas Fulop
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-27
Handbook On Immunosenescence written by Tamas Fulop and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-27 with Medical categories.
This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
Tissue Resident Memory T Cells
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Author : Fathia Mami-Chouaib
language : en
Publisher: Frontiers Media SA
Release Date : 2019-08-19
Tissue Resident Memory T Cells written by Fathia Mami-Chouaib and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-19 with categories.
Tissue-resident memory T (TRM) cells play a major role in control of viral infections. Their involvement in cancer diseases has been more recently demonstrated. This non-circulating T-lymphocyte subset lacks molecules enabling egress from the tissue and migration to lymph nodes, expresses specific markers of residency and displays specific transcription factors. The present special issue elucidates our current knowledge on CD8+ TRM cells and explores less frequently described resident subsets, such as CD4+ TRM and innate-like cells, as well as their specific metabolism and niches for their formation in infectious and cancer diseases.