T Cell Subsets And Cytokines Interplay In Infectious Diseases
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T Cell Subsets And Cytokines Interplay In Infectious Diseases
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Author : Mustafa A.S.
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 1996
T Cell Subsets And Cytokines Interplay In Infectious Diseases written by Mustafa A.S. and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
Presenting a wealth of new data on the interaction among T-cell subsets and cytokines, this book offers a fresh perspective on infectious diseases. It provides useful insights into the nature and treatment of helminthic and mycobacterial infections, with special emphasis on leprosy, leishmaniasis, malaria and trypanosomiasis. The outcome of the host response to infectious agent is seen as depending upon the T-cell subsets activated and the cytokines produced by them and other cells, such as macrophages, B cells and basophils. Experts contributions shed new light on how TH0 cells are preferentially activated and differentiated into TH1 or TH2 subsets; TH1 and TH2 cells and their cytokines induce both protective immune responses and adverse immune reactions to infectious agents; cytokines modulate the response of infectious diseases to chemotherapy; and cytokines, their receptors and antagonist, and anti-cytokine antibodies can be used in therapy. Those working in the fields of immunology, parasitology, microbiology and vaccine development particularly if they are interested in tropical diseases, will find the volume an invaluable source of information.
International Conference T Cell Subsets And Cytokines Interplay In Infectious Diseases
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Author :
language : en
Publisher:
Release Date : 1993
International Conference T Cell Subsets And Cytokines Interplay In Infectious Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Communicable diseases categories.
T Cell Subsets In Infectious And Autoimmune Diseases
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
T Cell Subsets In Infectious And Autoimmune Diseases written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
T cells are a specialized population of immune cells that aid the immune system in combating various types of invading pathogens. This book presents up-to-the-minute data on the role of T cells in autoimmune diseases.
The Interplay Between Immune Activation And Cardiovascular Disease During Infection Autoimmunity And Aging The Role Of T Cells
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Author : Marta Catalfamo
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-25
The Interplay Between Immune Activation And Cardiovascular Disease During Infection Autoimmunity And Aging The Role Of T Cells written by Marta Catalfamo and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-25 with Medical categories.
Cd4 T Cell Differentiation In Infection Amendments To The Th1 Th2 Axiom
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Author : Dragana Jankovic
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-03
Cd4 T Cell Differentiation In Infection Amendments To The Th1 Th2 Axiom written by Dragana Jankovic and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-03 with Immunologic diseases categories.
CD4+ T lymphocytes play an essential role in host defense against bacterial, parasitic and viral infections. During infection, under the influence of intrinsic signals received through peptide-MHC/TCR interactions and extrinsic signals provided by pathogen-conditioned dendritic and other accessory cells, CD4+ T cells proliferate and differentiate into specialized T helper (Th) effectors, which produce distinct sets of cytokines tailored to combat a specific class of microbes. The concept of CD4+ T cell multi-functionality was developed after the seminal discovery of Th1 and Th2 cells nearly 30 years ago. Although the Th1/Th2 paradigm has successfully withstood the test of time, in the past decade additional Th subsets (Th17, Tfh, Th22, Th9) have been identified. Similarly, single cell analyses of cytokines and master transcriptional factors have revealed that, at the population level, CD4+ T cell responses are far more heterogeneous than initially anticipated. While some of the checkpoints in Th cell specification have been identified, recent studies of transcriptional and epigenetic regulation have uncovered a significant flexibility during the course CD4+ T lymphocyte polarization. In addition, Th cells expressing cytokines with counteracting functions, as a measure of self-regulation, display yet another level of diversity. Understanding the mechanisms that control the balance between stability vs. plasticity of Th effectors both at the time of initiation of immune response and during development of CD4 T cell memory is critical for the rational design of better vaccines and new immunotherapeutic strategies. This research topic will cover current views on Th cell development, with a focus on the mechanisms that govern differentiation, function and regulation of effector Th cells in the context of microbial infections.
Janeway S Immunobiology
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Author : Kenneth Murphy
language : en
Publisher: Garland Science
Release Date : 2010-06-22
Janeway S Immunobiology written by Kenneth Murphy and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-22 with Medical categories.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Signaling Mechanisms Regulating T Cell Diversity And Function
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Author : Jonathan Soboloff
language : en
Publisher: CRC Press
Release Date : 2017-03-27
Signaling Mechanisms Regulating T Cell Diversity And Function written by Jonathan Soboloff and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-27 with Medical categories.
T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.
Persistent Viral Infections
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Author : R. Ahmed
language : en
Publisher: Wiley-Blackwell
Release Date : 1999
Persistent Viral Infections written by R. Ahmed and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.
Treating Infectious Diseases In A Microbial World
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2006-01-03
Treating Infectious Diseases In A Microbial World written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-03 with Medical categories.
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.