Targeting Epigenetics In Inflammatory Lung Diseases

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Targeting Epigenetics In Inflammatory Lung Diseases

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Author : Gaurav Gupta
language : en
Publisher: Springer Nature
Release Date : 2023-12-20

Targeting Epigenetics In Inflammatory Lung Diseases written by Gaurav Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-20 with Medical categories.

This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‐related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.

Lung Cancer And Environmental Toxicants

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Author : Kamal Dua
language : en
Publisher: Academic Press
Release Date : 2025-05-23

Lung Cancer And Environmental Toxicants written by Kamal Dua and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-05-23 with Science categories.

Lung Cancer and Environmental Toxicants aims to explore the intricate relationship between lung cancer and environmental toxicants, shedding light on a hidden link that demands urgent attention. This groundbreaking book addresses a critical gap in the current literature by introducing a pioneering exploration of the interplay between lung cancer and environmental toxicants. Previous articles have not coalesced into a comprehensive examination of the complex connection between lung cancer development and the diverse array of environmental toxicants. This book delves into the latest scientific research and clinical findings to offer a clear way forward for healthcare workers to assess and treat lung cancer patients who may have been exposed to these substances. "Lung Cancer and Environmental Toxicants" provides a precise view of the impact of environmental toxicants on lung cancer, covering various aspects including epidemiology, molecular mechanisms, exposure pathways, and preventive measures. This unique and timely work will pave the way for a deeper understanding of the underexplored factors contributing to lung cancer incidence, offering novel insights into the role of various toxic substances in disease causation. This significant title will catalyze new avenues of research and awareness in the fields of oncology, environmental health, and public policy. - Unlocks the intricate nexus between lung cancer and environmental toxicants, offering an unprecedented exploration of complex mechanisms and interactions for advancing research in oncology and environmental health - Takes a global perspective on lung cancer and environmental toxicants, considering the prevalence of the disease and its causes in different regions of the world, as well as addressing the challenges faced by developing nations - Presents rigorous, evidence-based research on the effects of toxicants on the human lung, ensuring the book's indispensability

Gut Microbiome And Environmental Toxicants

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Author : Gaurav Gupta
language : en
Publisher: CRC Press
Release Date : 2025-04-14

Gut Microbiome And Environmental Toxicants written by Gaurav Gupta and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-14 with Business & Economics categories.

This book comprehensively reviews the intricate relationship between environmental toxicants and the gut microbiome. It explores the role of dietary choices and lifestyle in shaping and modulating the gut microbiome’s response to environmental toxicants. It examines the intricate relationship between these toxic substances and the composition, function, and overall health implications of the gut microbiome. The chapters provide in-depth insights into the impacts of various toxicants, such as phthalates, pesticides, organic pollutants, bisphenols, and heavy metals, on the delicate microbial balance within our digestive systems. Specific chapters address the impact of lead, mercury, cadmium, and arsenic on the composition and function of the gut microbiome. The book concludes by addressing future prospects and challenges in understanding and mitigating the impacts of environmental toxicants on the gut microbiome and highlighting the importance of these efforts. Key Features: Provides a comprehensive examination of the intricate relationship between environmental toxicants and the gut microbiome Reviews the possible mechanisms underlying bidirectional interactions between environmental pollutants and GI Examines the role of dietary choices and lifestyle factors in modulating the gut microbiome's response to environmental toxicants Covers the impact of toxic substances, phthalates, pesticides, and heavy metals on the gut microbiome Explores the practical implications of toxicant exposure on human health This book is intended for researchers and scientists working in the fields of environmental toxicology, microbiology, pharmacology, and related disciplines.

Role Of Gut Microbiota And Postbiotics For Colorectal Cancer

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Author : Neeraj Mishra
language : en
Publisher: Springer Nature
Release Date : 2025-07-01

Role Of Gut Microbiota And Postbiotics For Colorectal Cancer written by Neeraj Mishra and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-01 with Medical categories.

The emerging role of gut microbiota and postbiotics has implications for the management of not only human health and diseases, but also colorectal cancer in particular, as these elements influence colorectal cancer pathogenesis, treatment, and prevention. This book bridges the gap between cutting-edge research and practical clinical applications in the management of colorectal cancer by offering a fresh perspective on potential therapeutic strategies and exploring the significance of microbiota in the oncology landscape. Chapters delve into the specific impacts of postbiotics, linking them to immune response modulation, inflammation reduction, and direct anticancer effects. Chapters also explore current and emerging therapies, including the manipulation of gut microbiota and the use of postbiotics supplements. Clinical trial results, case studies, and expert opinions are interwoven to present a realistic view of the benefits, limitations, and future prospects of these innovative therapeutic strategies. This book is rounded out with perspectives on future research directions in this area, discussing potential next-generation therapies such as personalized medicine approaches and biotechnological advancements, and further contemplating broader implications of microbiota research on public health strategies. Informative and engaging, this book provides clinicians and researchers alike with a deeper understanding of how postbiotics can be harnessed in colorectal cancer treatment and potentially, the treatment of other cancers influenced by gut health.

Decoding Dna Methylation

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Author : Dr. Sivakumar Vijayaraghavalu
language : en
Publisher: OrangeBooks Publication
Release Date : 2025-02-23

Decoding Dna Methylation written by Dr. Sivakumar Vijayaraghavalu and has been published by OrangeBooks Publication this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-02-23 with Science categories.

“Decoding DNA Methylation” explores the pivotal role of DNA methylation in gene regulation, genome stability and diseases. This book bridges fundamental biology with clinical applications by covering key mechanisms, including DNA methyltransferases, methylation dynamics, and their interplay with histone modifications. It examines methylation’s impact on cancer, neurological disorders and epigenetic inheritance, highlighting emerging biomarkers and therapeutic strategies. With insights into environmental influences and precision medicine, this book serves as a resource for researchers, clinicians, and students seeking to understand epigenetics in health and disease.

Single Cell Sequencing And Methylation

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Author : Buwei Yu
language : en
Publisher: Springer Nature
Release Date : 2020-09-19

Single Cell Sequencing And Methylation written by Buwei Yu and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-19 with Science categories.

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients.

The Epigenetics Of Autoimmunity

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Author : Rongxin Zhang
language : en
Publisher: Academic Press
Release Date : 2018-04-25

The Epigenetics Of Autoimmunity written by Rongxin Zhang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-04-25 with Medical categories.

The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sjögren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment. - Provides the accurate and cutting-edge information on autoimmunity epigenetics - Wide coverage appeals to those interested in fundamental epigenetics and inheritance to those with more clinical interests - Critical reviews of the mean of deriving and analysing autoimmunity epigenetics information as well as its translational potential - Up-to-date coverage of emerging topics in autoimmunity epigenetics

Alcohol Research

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Author :
language : en
Publisher:
Release Date : 2013

Alcohol Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with Alcoholism categories.

The Role Of Epigenetics In Infectious Diseases

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Author : Veron Ramsuran
language : en
Publisher: Frontiers Media SA
Release Date : 2023-03-08

The Role Of Epigenetics In Infectious Diseases written by Veron Ramsuran and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-08 with Medical categories.

Epigenetics In Human Disease

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Author : Trygve Tollefsbol
language : en
Publisher: Academic Press
Release Date : 2012-07-26

Epigenetics In Human Disease written by Trygve Tollefsbol and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-26 with Medical categories.

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs