Targeting Of Drugs
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Targeting Of Drugs 4
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Author : Gregory Gregoriadis
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Targeting Of Drugs 4 written by Gregory Gregoriadis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
The NATO Advanced Studies Institute series "Targeting of Drugs" was originated in 1981. It is now a major international forum, held every two years in Cape Sounion, Greece, in which the present and the future of this important area of research in drug delivery is discussed in great depth. Previous ASIs of the series dealt with drug carriers of natural and synthetic origin, their interaction with the biological milieu, ways by which the latter influences such interaction, strategies by which milieu interference curtailing the function of drug carriers is circumvented and, more recently, with the application of drug carriers for the delivery of peptides and proteins. The present book contains the of the 7th NATO ASI "Targeting of Drugs: Advances in System Constructs", proceedings held in Cape Sounion during 24 June -5 July 1993. As the title implies, the book deals with a variety of approaches to carrier design or modification that contribute to optimal carrier function. to Mrs Concha Perring for her assistance with the We express our appreciation organization of the ASI. We thank Dr. G. Deliconstantinos who, as chairperson of the Local Committee, contributed to the success of the Institute. The ASI was held under the sponsorship of NATO Scientific Affairs Division and co-sponsored and generously financed by SmithKline Beecham Pharmaceuticals (King of Prussia). Financial assistance was also provided by Liposome Technology Inc. (Menlo Park), Vestar Inc. (San Dimas) and Zeneka (Macclesfield).
Targeting Of Drugs
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Author : Gregory Gregoriadis
language : en
Publisher: Springer
Release Date : 2012-12-12
Targeting Of Drugs written by Gregory Gregoriadis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-12 with Medical categories.
Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.
Targeted Drug Delivery Concepts And Design
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Author : Padma V. Devarajan
language : en
Publisher: Springer
Release Date : 2014-12-08
Targeted Drug Delivery Concepts And Design written by Padma V. Devarajan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-08 with Medical categories.
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.
Targeting Of Drugs 2
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Author : Gregory Gregoriadis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Targeting Of Drugs 2 written by Gregory Gregoriadis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1989
Fasttrack Pharmaceutics
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Author : Yvonne Perrie
language : en
Publisher: Pharmaceutical Press
Release Date : 2012
Fasttrack Pharmaceutics written by Yvonne Perrie and has been published by Pharmaceutical Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
"Pharmaceutics - Drug delivery and targeting focuses on what pharmacy students really need to know in order to pass exams, providing concise, bulleted information, key points, tips and an all-important self-assessment section which includes MCQs."--Page 4 of cover.
Targeting Of Drugs
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Author : Gregory Gregoriadis
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Targeting Of Drugs written by Gregory Gregoriadis and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.
Concepts And Misconceptions Of Drug Targeting
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Author : Karel Petrak
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-08-05
Concepts And Misconceptions Of Drug Targeting written by Karel Petrak and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-05 with Medical categories.
Precision medicine requires precision drugs that match the needs of individual patients. An ideal drug, popularly referred to as the “magic bullet”, should be effective without causing any unwanted side effects. To do this, drugs must act solely on the target of the disease. Despite major efforts in this area over some 50 years, the currently available drugs are far from being “idea”. This book summarizes the key requirements for developing precision drugs and offers a new paradigm for site-specific drug delivery. As such, it will be of interest to personnel involved in drug development at pharmaceutical and biotech companies and academic institutions.
Drug Targeting Technology
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Author : Hans Schreier
language : en
Publisher: CRC Press
Release Date : 2001-08-09
Drug Targeting Technology written by Hans Schreier and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-08-09 with Medical categories.
Demonstrates how substitution of a variety of ligands can render albumin a versatile targeting tool for selective drug accumulation in various cell populations of the liver! This book discusses physical, chemical, and biological approaches to drug targeting technology, focusing on oral, dispersed system, topical, dermal, transdermal, and inh
Drug Targeting And Stimuli Sensitive Drug Delivery Systems
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Author : Alexandru Mihai Grumezescu
language : en
Publisher: William Andrew
Release Date : 2018-05-21
Drug Targeting And Stimuli Sensitive Drug Delivery Systems written by Alexandru Mihai Grumezescu and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-21 with Science categories.
Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy
Organ Specific Drug Delivery And Targeting To The Lungs
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Author : Ajit S. Narang
language : en
Publisher: CRC Press
Release Date : 2022-11-22
Organ Specific Drug Delivery And Targeting To The Lungs written by Ajit S. Narang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-22 with Medical categories.
Organ Specific Drug Delivery and Targeting to the Lungs provides up to date information on the multidisciplinary field of particle engineering and drug delivery to the lungs, including advancements of nanotechnology. The text presents a unique, pragmatic focus with case studies, that help translate scientific understanding to practical implementation. In addition to highlighting the successful case studies, it also offers practical advice on watchouts, limitations, and ‘bookend’ boundaries involved in the stages of testing and development. Additional Features Include: Provides an account of particle engineering, discovery, biology, development, and delivery in relation with the advancements of nanotechnology, unlike any previous book. Brings together the leading experts and researchers in the field to critically assess and discuss various topics influencing drug delivery. Highlights the interplay of different scientific disciplines and the balance of requirements that are critical to molecule and product design. With the strategic focus on what matters during new product development, this book provides a guide to understanding and navigating new drug discovery and development for lung targets.