Targeting Oral Cancer


Targeting Oral Cancer
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Targeting Oral Cancer


Targeting Oral Cancer
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Author : Andrew Fribley
language : en
Publisher: Springer
Release Date : 2016-02-29

Targeting Oral Cancer written by Andrew Fribley and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-29 with Medical categories.


This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation.



Textbook Of Oral Cancer


Textbook Of Oral Cancer
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Author : Saman Warnakulasuriya
language : en
Publisher: Springer Nature
Release Date : 2020-02-22

Textbook Of Oral Cancer written by Saman Warnakulasuriya and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-22 with Medical categories.


This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.



Screening For Oral Cancer


Screening For Oral Cancer
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Author : U. S. Department of Health and Human Services
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2013-05-28

Screening For Oral Cancer written by U. S. Department of Health and Human Services and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-28 with Medical categories.


In 2004, the U.S Preventive Services Task Force (USPSTF) found insufficient evidence in its review to recommend for or against screening for oral cancer. In this review, we are updating the evidence search and analysis to allow this recommendation to be reconsidered. Oral cancer includes cancers of the lip, oral cavity, and pharynx. Ninety percent of cancers of the oral cavity are squamous cell carcinomas (SCCs) arising from the mucosal lining. The other 10 percent of oral cancers are malignant melanomas, salivary gland tumors, sarcomas of the soft tissues or jaw bones, nonHodgkin's lymphomas, or metastases from extra-oral primary tumors. The USPSTF requested this targeted update to focus on the evidence gap in the conceptual framework about screening for oral cancer (i.e., any test or combination of tests used to detect PMDs or cancer of the lip, oral cavity, or pharynx). The two key questions are: Key Question 1 (KQ 1): Does screening for oral cancer reduce morbidity or mortality? Key Question 2 (KQ 2): What are the performance characteristics of the screening oral examination as a means of identifying oral cancer or PMDs for oral cancer?



Oral Squamous Cell Carcinoma


Oral Squamous Cell Carcinoma
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Author : Matthew Rabin
language : en
Publisher: Nova Science Publishers
Release Date : 2021

Oral Squamous Cell Carcinoma written by Matthew Rabin and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Medical categories.


"This monograph consists of five chapters that describe the diagnosis and treatment of oral squamous cell carcinoma (OSCC), which is the most common malignant epithelial neoplasm affecting the oral cavity. Chapter One deals with different potentially malignant disorders in the development of OSCC, diagnostic methods of OSCC, the pertinence of biomarkers in OSCC therapy, classification of biomarkers, existing biomarkers in different stages of OSCC and the challenges of developing new biomarkers. Chapter Two is focused on principles, systems, technologies, therapeutic approaches, safety and toxicity and patents comprising drug delivery systems for local oral squamous cell carcinoma treatment. Chapter Three aims to highlight a detailed critical review of previous literature on putative cancer stem cell pathways for oral carcinoma and draw interest in targeting the most common cancer stem cell markers as a therapeutic regimen for oral cancer preneoplastic tumors, metastasis, and treatment progression. Chapter Four aims to cover the recent developments in nanotechnology-based drug delivery systems, advanced nanomedicines and their diagnostics as well as therapeutic applications in OSCC. Finally, Chapter 5 aims to elaborate on the importance of biomarkers as an early diagnostic tool in detecting oral squamous cell carcinoma"--



Controversies In Oral Cancer


Controversies In Oral Cancer
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Author : K. Alok Pathak
language : en
Publisher: Springer
Release Date : 2015-10-30

Controversies In Oral Cancer written by K. Alok Pathak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-30 with Medical categories.


This volume brings together the work of experts from clinical and basic sciences specialties and addresses some of the controversial issues and advances in the management of oral cancer. Improving the outcome for the oral cancer patient will require dedicated work from many disciplines working together as multidisciplinary units. The book is meant for medical students, residents and consultants in various disciplines, including otolaryngology, head and neck surgery, neurosurgery, plastic surgery, maxillofacial surgery and oncology.



Oral Cancer


Oral Cancer
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Author : Jatin P. Shah
language : en
Publisher: Thieme
Release Date : 2003

Oral Cancer written by Jatin P. Shah and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Medical categories.


Oral cancer is the sixth most common cancer worldwide. This authoritative international text unites the experience of specialists from both sides of the Atlantic and comprehensively addresses all aspects of the biology, etiology and pathology or oral cancer as well as clinical assessment, surgery, adjuvant therapies and post-treatment rehabilitation of the oral cancer patient. With over 550 illustrations, the majority of which are in full color, this book is a valuable and essential resource for any specialist working in the field of oral cancer.



Textbook Of Oral Cancer


Textbook Of Oral Cancer
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Author :
language : en
Publisher:
Release Date : 2020

Textbook Of Oral Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Electronic books categories.


This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors - all experts in the field of oral oncology - provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.



Oral Cancer Metastasis


Oral Cancer Metastasis
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Author : Jeffrey Myers
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-11-11

Oral Cancer Metastasis written by Jeffrey Myers and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Medical categories.


Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region. Despite improvements in treatment, the survival of patients with SCCOC has not significantly improved over the past several decades. Most frequently, treatment failure takes the form of local and regional recurrences, but as disease control in these areas improves, SCCOC treatment failures more commonly occur as distant metastasis. The presence of cervical lymph node metastasis is the most reliable adverse prognostic factor in patients with SCCOC, and extracapsular spread (ECS) of cervical lymph nodes metastasis is a particularly reliable predictor of regional and distant recurrence and death from disease. Decisions regarding elective and therapeutic management of cervical lymph node metastases are made mainly on clinical grounds as we cannot always predict cervical lymph node metastasis from the size and extent of invasion of the primary tumors. Therefore the treatment of the neck disease in the management of SCCOC remains controversial. The promise of using biomarker-based treatment decisions has yet to be fully realized due to our poor understanding of the mechanisms of regional and distant metastases of SCCOC. We will summarize the current status of investigations into SCCOC metastases and potential of these studies to impact basic research investigators and clinicians confronting SCCOC in the future.



Inflammation And Oral Cancer


Inflammation And Oral Cancer
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Author : Hiroyuki Tomita
language : en
Publisher: Academic Press
Release Date : 2021-09-01

Inflammation And Oral Cancer written by Hiroyuki Tomita and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-01 with Science categories.


Inflammation and Oral Cancer: From Bench to Bedside discusses all aspects surrounding the relationship between inflammation and oral cancer, from basic science to the translational research that helps in the optimization of clinical management strategies. The book discusses topics such as chronic inflammation and cancer in oral cavity, the role of HPV in oral inflammation and cancer, rodent models of oral cancer, and epigenetics in oral inflammation and cancer. This is a valuable resource for cancer researchers, oncologists and members of biomedical field who are interested in learning more about the diverse aspects of inflammation and oral cancer. Inflammation in oral mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it can have fundamental clinical consequences, the principal of which can be premalignant lesions throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for oral cancer - therefore it is very important to understand these interactions in detail. Presents animal models of oral cancers for use in research Discusses epigenetics in oral cancers, along with risk factors such as tabaco and alcohol Encompasses detailed information on human papilloma virus (HPV) and its risk in oral inflammation and cancer



Contemporary Issues In Oral Cancer


Contemporary Issues In Oral Cancer
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Author : Dhananjaya Saranath
language : en
Publisher: Oxford University Press, USA
Release Date : 2000

Contemporary Issues In Oral Cancer written by Dhananjaya Saranath and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Medical categories.


This book lays emphasis on various therapeutic approaches in head and neck cancers, including surgery, radiation therapy and photodynamic laser therapy. Other important topics discussed are the integration of surgery/radiation therapy with chemotherapy for better patient managemnet andfeasibility of immunotherapy and gene therapy in oral cancers, outlining the different therapeutic modalities. This book makes interesting reading for both biologists and doctors in research and clinical practice.