Telomere Biology
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Reviews On Selected Topics Of Telomere Biology
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Author : Bibo Li
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-11-14
Reviews On Selected Topics Of Telomere Biology written by Bibo Li and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-14 with Medical categories.
Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases. Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions. This book includes current opinions on selected aspects of telomere research and their implication, in hope to help us focus better on future studies and enhance our research progress.
Telomere
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Author : Marcelo Larramendy
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-11-23
Telomere written by Marcelo Larramendy and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-23 with Medical categories.
This book, Telomere - A Complex End of a Chromosome, is organized into nine chapters containing the latest aspects of the current knowledge about the structure of telomeres and the crucial role that telomerase plays not only in maintaining chromosomal stability but also in relation to cell immortality, cell instability, and cancer biology. We now appreciate that these unusual complexes of DNA and proteins we all know as "telomeres" are dynamic and key structures that depend on telomerase and other cellular factors for continuance. Regulation of telomere activity is a dynamic area of current research, and new insights into telomeres and their role in aging and cancer, among other biological functions and pathologies, appear regularly in the scientific world. However, one fact is more than understandable in this difficult biological conundrum: the end of the telomere story is far from being totally unraveled.
Telomere Biology
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Author : Jerome Fucile
language : en
Publisher:
Release Date : 2015-03-18
Telomere Biology written by Jerome Fucile and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-18 with Science categories.
This book extensively discusses the biology of telomere with the help of advanced information. Developments in telomere researches have provided an interrelation of telomere dysfunction with cellular aging and several age-related human diseases. Some new findings and studies have further widened our knowledge of telomere functions, where telomeres have been demonstrated to be essential for microbial pathogen virulence and telomere proteins have significant non-telomeric cellular functions. This book presents current opinions on selected areas of telomere research and their implication, in the hope of benefitting interested individuals in their future studies and enhancing their research progress.
Telomeres In Health And Disease
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Author :
language : en
Publisher: Academic Press
Release Date : 2014-06-26
Telomeres In Health And Disease written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-26 with Science categories.
This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field. Contributions from specialists in telomere diseases Informs and updates on how telomere dysfunction may cause disease in humans
Telomeres
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Author : Titia De Lange
language : en
Publisher:
Release Date : 2006
Telomeres written by Titia De Lange and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Medical categories.
An up-to-date survey of the current exciting state of telomere biology. Telomeres – specialized structures found at the ends of chromosomes – are essential for maintaining the integrity of chromosomes and their faithful duplication during cell division. Chapters in this volume cover telomere structure and function in a range of organisms, focusing on how they are maintained, their roles in cell division and gene expression, and how deficiencies in these structures contribute to cancers and other diseases and even aging.
Telomerases Telomeres And Cancer
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Author : Guido Krupp
language : en
Publisher: Springer
Release Date : 2010-12-05
Telomerases Telomeres And Cancer written by Guido Krupp and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-05 with Science categories.
This volume provides broad insights to the most recent discoveries in telomere biology, with current applications in tumor diagnostics and future potentials in therapy. Special features of diverse organisms are presented, with ciliates, the "telomerase discoverer organisms"; yeasts, the "molecular genetisists' toy for eukaryotes"; including plants and insects as well. 28 chapters were written by a group of leading research scientists, working in the telomere/telomerase fields today. This book will be a core reference for any physician, scientist or "educated reader" with an interest in the exciting developments in this research field.
Telomerase And Non Telomerase Mechanisms Of Telomere Maintenance
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Author : Tammy A. Morrish
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-04-01
Telomerase And Non Telomerase Mechanisms Of Telomere Maintenance written by Tammy A. Morrish and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-01 with Science categories.
This book, Telomerase and non-Telomerase Mechanisms of Telomere Maintenance, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of biochemistry, genetics, and molecular biology. The book comprises single chapters authored by various researchers and edited by an expert active in the molecular biology research area. All chapters are individually complete but united under a common research topic. This publication aims to provide a thorough overview of the latest research efforts by international authors on biochemistry, genetics,and molecular biology, and open new possible research paths for further novel developments. A note from the publisher: It is with great sadness and regret that we inform the contributing authors and readers of this book that the Editor, Dr Tammy A. Morrish, passed away during the publishing process of the book and before having a chance to see its publication. The book Telomerase and non-Telomerase Mechanisms of Telomere Maintenance was her first edited volume with us. Fruitful collaboration continued until her final days. We would like to acknowledge Dr Morrish's contribution to scientific publishing, which she made during years of dedicated work, and express our gratitude for her pleasant cooperation with us.
Telomerases
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Author : Neal F. Lue
language : en
Publisher: John Wiley & Sons
Release Date : 2012-06-26
Telomerases written by Neal F. Lue and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-06-26 with Science categories.
This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed.
Telomeres Diet And Human Disease
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Author : Amelia Marti
language : en
Publisher: CRC Press
Release Date : 2017-08-30
Telomeres Diet And Human Disease written by Amelia Marti and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-30 with Medical categories.
The maintenance of telomeres—repetitive sequences at the end of chromosome—is essential to health. Dysfunction in telomere maintenance pathways plays a role in aging, cancer, atherosclerosis and other diseases. This has led to telomere maintenance as a prime target for patient therapies. This book describes the advances in telomere research as it applies to human health and especially how lifestyle and dietary factors could modify the telomerase maintenance process. The book examines the mechanisms involved, the primary of which are oxidative stress and the role of sirtuins, and how they can be modified by dietary patterns such as Mediterranean diet.
Elizabeth Blackburn And The Story Of Telomeres
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Author : Catherine Brady
language : en
Publisher: MIT Press
Release Date : 2009-02-13
Elizabeth Blackburn And The Story Of Telomeres written by Catherine Brady and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-13 with Biography & Autobiography categories.
The story of molecular biologist Elizabeth Blackburn and her groundbreaking research on telomeres and what it reveals about the resourceful opportunism that characterizes the best scientific thinking. Molecular biologist Elizabeth Blackburn—one of Time magazine's 100 “Most Influential People in the World” in 2007—made headlines in 2004 when she was dismissed from the President's Council on Bioethics after objecting to the council's call for a moratorium on stem cell research and protesting the suppression of relevant scientific evidence in its final report. But it is Blackburn's groundbreaking work on telomeric DNA, which launched the field of telomere research, that will have the more profound and long-lasting effect on science and society. In this compelling biography, Catherine Brady tells the story of Elizabeth Blackburn's life and work and the emergence of a new field of scientific research on the specialized ends of chromosomes and the enzyme, telomerase, that extends them. In the early stages of telomere research, telomerase, heralded as a potential cure for cancer and diseases related to aging, attracted the voracious interest of biotech companies. The surrounding hype succeeded in confusing the role of telemorase in extending the life of a cell with a mechanism that might extend the lifespan of an entire organism. In Brady's hands, Blackburn's story reveals much about the tension between pure and applied science, the politicking that makes research science such a competitive field, and the resourceful opportunism that characterizes the best scientific thinking. Brady describes the science accessibly and compellingly. She explores Blackburn's struggle to break down barriers in an elite, male-dominated profession, her role as a mentor to other women scientists (many of whom have made their mark in telomere research), and the collaborative nature of scientific work. This book gives us a vivid portrait of an exceptional woman and a new understanding of the combination of curiosity, imaginative speculation, and aesthetic delight that powers scientific discovery.