Reviews On Selected Topics Of Telomere Biology
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Reviews On Selected Topics Of Telomere Biology
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Author : Bibo Li
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-11-14
Reviews On Selected Topics Of Telomere Biology written by Bibo Li and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-14 with Medical categories.
Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases. Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions. This book includes current opinions on selected aspects of telomere research and their implication, in hope to help us focus better on future studies and enhance our research progress.
Reviews On Selected Topics Of Telomere Biology
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Author : Bibo Li
language : en
Publisher:
Release Date : 2012
Reviews On Selected Topics Of Telomere Biology written by Bibo Li and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Telomeres, located at the ends of linear chromosomes, are essential for genome stability and integrity. Advances in telomere researches have linked telomere dysfunction with cellular aging and a number of age-related human diseases. Recent studies further expanded our knowledge of telomere functions - telomeres are shown to be important for microbial pathogen virulence and telomere proteins have important non-telomeric cellular functions. This book includes current opinions on selected aspects of telomere research and their implication, in hope to help us focus better on future studies and enhance our research progress.
Enzyme Inhibitors And Activators
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Author : Murat Şentürk
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-03-29
Enzyme Inhibitors And Activators written by Murat Şentürk and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-29 with Science categories.
Over the recent years, medicinal chemistry has become responsible for explaining interactions of chemical molecule processes such that many scientists in the life sciences from agronomy to medicine are engaged in medicinal research. This book contains an overview focusing on the research area of enzyme inhibitor and activator, enzyme-catalyzed biotransformation, usage of microbial enzymes, enzymes associated with programmed cell death, natural products as potential enzyme inhibitors, protease inhibitors from plants in insect pest management, peptidases, and renin-angiotensin system. The book provides an overview on basic issues and some of the recent developments in medicinal science and technology. Especially, emphasis is devoted to both experimental and theoretical aspect of modern medicine. The primary target audience for the book includes students, researchers, chemists, molecular biologists, medical doctors, pharmacologists, and professionals who are interested in associated areas. The textbook is written by international scientists with expertise in biochemistry, enzymology, molecular biology, and genetics, many of which are active in biochemical and pharmacological research. I would like to acknowledge the authors for their contribution to the book. We hope that the textbook will enhance the knowledge of scientists in the complexities of some medical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of pharmacology.
Rediscovering Cancer From Mechanism To Therapy
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Author : Sayali Mukherjee
language : en
Publisher: CRC Press
Release Date : 2018-09-04
Rediscovering Cancer From Mechanism To Therapy written by Sayali Mukherjee and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-04 with Medical categories.
This volume presents a snapshot of some of the most important ongoing research in cancer. With cancer as the second leading cause of death worldwide, extensive research is going on globally to decipher the molecular mechanism underlying cancer that will help in finding better targets for drug therapy. The book brings together new research on molecular mechanism and cancer therapeutics in one place. With chapters from experts in their respective fields, chapters cover molecular mechanisms, etiology, prognosis, detection, and treatment of cancer. Emphasis has been given to the intricate mechanism behind the deregulation of cell division, disruption of cell cycle check points, mutation in oncogenes and tumor suppressor genes, apoptosis, and erratic cell signaling. The book discusses in detail topics such as angiogenesis and tumor microenvironment, which are increasingly receiving attention, especially in the field of neoplastic vascularization and metastasis. The book also includes chapters detailing the current understanding and the future perspective of cancer stem cells.
Marine Genomics
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Author : Cinzia Verde
language : en
Publisher: Springer Nature
Release Date : 2022-06-21
Marine Genomics written by Cinzia Verde and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-21 with Science categories.
This detailed volume provides an overview of recent advances in the application of genomic technologies in several domains of marine biology, raising awareness of various DNA- and RNA-based technologies. Genomic methods are essential in identifying previously undetected taxonomic (e.g. DNA barcoding), genetic (e.g. sequencing), and functional (e.g. gene expression, analysis of metabolites) diversity, as shown in the chapters of this book, with sections focusing on next generation sequencing (NGS) technologies, bioinformatics in marine genomics research, marine biotechnology, as well as a variety of methods successfully applied in fish. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Marine Genomics: Methods and Protocols highlights the utility of numerous lab protocols and their potential to provide deeper insight into physiological and ecological mechanisms in marine life.
Cellular Senescence And Tumor Suppression
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Author : Peter D. Adams
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-01-23
Cellular Senescence And Tumor Suppression written by Peter D. Adams and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-23 with Medical categories.
As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.
The Telomere Effect
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Author : Dr. Elizabeth Blackburn
language : en
Publisher: Grand Central Publishing
Release Date : 2017-01-03
The Telomere Effect written by Dr. Elizabeth Blackburn and has been published by Grand Central Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-03 with Health & Fitness categories.
The New York Times bestselling book coauthored by the Nobel Prize winner who discovered telomerase and telomeres' role in the aging process and the health psychologist who has done original research into how specific lifestyle and psychological habits can protect telomeres, slowing disease and improving life. Have you wondered why some sixty-year-olds look and feel like forty-year-olds and why some forty-year-olds look and feel like sixty-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection. They and other scientists have found that changes we can make to our daily habits can protect our telomeres and increase our health spans (the number of years we remain healthy, active, and disease-free). The Telemere Effect reveals how Blackburn and Epel's findings, together with research from colleagues around the world, cumulatively show that sleep quality, exercise, aspects of diet, and even certain chemicals profoundly affect our telomeres, and that chronic stress, negative thoughts, strained relationships, and even the wrong neighborhoods can eat away at them. Drawing from this scientific body of knowledge, they share lists of foods and suggest amounts and types of exercise that are healthy for our telomeres, mind tricks you can use to protect yourself from stress, and information about how to protect your children against developing shorter telomeres, from pregnancy through adolescence. And they describe how we can improve our health spans at the community level, with neighborhoods characterized by trust, green spaces, and safe streets. The Telemere Effect will make you reassess how you live your life on a day-to-day basis. It is the first book to explain how we age at a cellular level and how we can make simple changes to keep our chromosomes and cells healthy, allowing us to stay disease-free longer and live more vital and meaningful lives.
Selected Topics In Dna Repair
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Author : Clark Chen
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-10-26
Selected Topics In Dna Repair written by Clark Chen and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-26 with Medical categories.
This book is intended for students and scientists working in the field of DNA repair, focusing on a number of topics ranging from DNA damaging agents and mechanistic insights to methods in DNA repair and insights into therapeutic strategies. These topics demonstrate how scientific ideas are developed, tested, dialogued, and matured as it is meant to discuss key concepts in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.
Telomere Biology
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Author : Jerome Fucile
language : en
Publisher:
Release Date : 2015-03-18
Telomere Biology written by Jerome Fucile and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-18 with Science categories.
This book extensively discusses the biology of telomere with the help of advanced information. Developments in telomere researches have provided an interrelation of telomere dysfunction with cellular aging and several age-related human diseases. Some new findings and studies have further widened our knowledge of telomere functions, where telomeres have been demonstrated to be essential for microbial pathogen virulence and telomere proteins have significant non-telomeric cellular functions. This book presents current opinions on selected areas of telomere research and their implication, in the hope of benefitting interested individuals in their future studies and enhancing their research progress.
Handbook Of Models For Human Aging
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Author : P. Michael Conn
language : en
Publisher: Elsevier
Release Date : 2011-04-28
Handbook Of Models For Human Aging written by P. Michael Conn and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-28 with Medical categories.
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. Utilizes a multidisciplinary approach Shows tricks and approaches not available in primary publications First volume of its kind to combine both methods of study for human aging and animal models Over 200 illustrations