Teratology
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Basic Concepts In Teratology
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Author : T. V. N. Persaud
language : en
Publisher: Alan R. Liss
Release Date : 1985
Basic Concepts In Teratology written by T. V. N. Persaud and has been published by Alan R. Liss this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Abnormalities categories.
Teratology
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Author : C.L. Berry
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratology written by C.L. Berry and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In the fifteen years since the thalidomide disaster teratology has become a science in its own right, distinct from its progenitors, experimental embryology and develop mental biology, but bearing many of the familiar features of both parents. In this growth period there have been contributions from many different scientific disciplines as diverse as molecular biology and obstetrics, which have united in the field of study of congenital malformations. Scientists in academic departments, government research institutes and industrial pharmacology have all explored ways of evaluating the potential of drugs and chem icals to damage the embryo; strict methods of screening for teratogenicity have be come mandatory in most parts of the world. Despite a wealth of basic information in the fields of genetics and embryology, there is little concrete knowledge of the causal mechanisms of malformation in Man, and even less concerning the relevance to Man of those laboratory and animal tests which decide the fate of potentially useful drugs. It is timely, therefore, that in 1975 a group of young and active sci entists and clinicians concerned with the broader implications of teratology should review the past and look to the future of this emerging speciality. In this volume the editors have blended the opinions of teratologists; their message presages change in many of the old and accepted areas of investigative teratology.
Teratology In The Twentieth Century Plus Ten
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Author : Harold Kalter
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-07-28
Teratology In The Twentieth Century Plus Ten written by Harold Kalter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-28 with Medical categories.
Serious congenital malformations are a major contributor to the infant death rate worldwide. Their nonhereditary causes are multiple and complex, and include infectious and metabolic dangers, disease medication, nutritional inadequacy, medicinal products, environmental agents and pollutants, among them. The cause of many however is still unknown. The wide range of these causes makes the defects of interest to those of a wide range of medical and investigatory backgrounds, especialy clinicians, fundamental scientists, and environmentalists.
Teratology In The Twentieth Century
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Author : H. Kalter
language : en
Publisher: Elsevier
Release Date : 2003-06-06
Teratology In The Twentieth Century written by H. Kalter and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-06 with Medical categories.
This book is an an up-to-date survey and summary of present knowledge and future expectations regarding the environmental causes of congenital malformations in human beings, beginning with the earliest discoveries of the 20th century up to the latest ideas and problems at its end, presents views and comments on the progress made over the century in understanding human prenatal maldevelopment.
Catalog Of Teratogenic Agents
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Author : Thomas H. Shepard
language : en
Publisher: JHU Press
Release Date : 2004
Catalog Of Teratogenic Agents written by Thomas H. Shepard and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Teratogenic agents categories.
Links information on experimental teratogenic agents with the congenital defects in human beings.
Mechanisms And Pathogenesis
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Author : James Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Mechanisms And Pathogenesis written by James Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Issues And Reviews In Teratology
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Author : Harold Kalter
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Issues And Reviews In Teratology written by Harold Kalter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Teratology is at once among the oldest and youngest of human preoccupations. Coincident with man's first observations of the stars were his recordings of human and animal deformities. But, such aberrancies must have occurred even earlier, for although it is one of those things-like evolution-that cannot be proven, it is nevertheless indisputable that dysmorphogenesis must have occurred from the time complex forms of life first arose on our planet; and that from the beginnings of human awareness our species was conscious of such happenings. From the earliest recordings of this fascination with the form and meaning of abnormality a tortuous but continuous line extends to modern struggles to understand and control these manifestations. And now, after long occupying an honorable but peripheral place in the halls of philosophical and scientific pursuits, teratology has quite suddenly come to take a prominent position at the hub of a complex crossroads of human concerns. This shift in its fortune has taken several forms. Fetal maldevelopment has become the concern of environmentalists, activists of various persuasions, indus trial organizations, government agencies, ethicists, parents-i. e. , individuals and groups whose actions are impelled by apprehension. Such motives are of course not without basis; the trauma of thalidomide left a scar yet raw. For still others clinicians, academics, experimentalists-the upsurge in the interest in fetal mal development is at a different level, and their pursuits are broad, taking external agents as but one of the causes of defective development.
Practical Teratology
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Author : Pamela Taylor
language : en
Publisher:
Release Date : 1986
Practical Teratology written by Pamela Taylor and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.
This book provides the practicing teratologist with up-to-date guidelines on how to conduct animal studies, and gives advice on the nomenclature and evaluation of anomalies. Written from a practical viewpoint, this will be an invaluable reference for daily use in the laboratory.
Teratological Testing
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Author : T.V.N. Persaud
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Teratological Testing written by T.V.N. Persaud and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mec.;hanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. The· contributions in this volume deal primarily with the areas of terato logical evaluation and the use of selected animal models for the study of con genital anomalies. It is not only a documentation of the latest experimental work, but it also indicates new and important areas for future research.
Issues And Reviews In Teratology
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Author : H. Kalter
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Issues And Reviews In Teratology written by H. Kalter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
''A valuable resource for those concerned with experimental teratology and risk assessment and those requiring general information about the causes of birth defects. The treatment of these issues is sophisticated, succinct, and logical.'' --- American Scientist, from a review of a previous volume The current volume covers intergenerational factors in pregnancy outcome, the thresholds for developmental toxicants, and four other subjects.