Testing Statistical Hypotheses Of Equivalence And Noninferiority
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Testing Statistical Hypotheses Of Equivalence And Noninferiority
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Author : Stefan Wellek
language : en
Publisher: CRC Press
Release Date : 2010-06-24
Testing Statistical Hypotheses Of Equivalence And Noninferiority written by Stefan Wellek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-06-24 with Mathematics categories.
While continuing to focus on methods of testing for two-sided equivalence, Testing Statistical Hypotheses of Equivalence and Noninferiority, Second Edition gives much more attention to noninferiority testing. It covers a spectrum of equivalence testing problems of both types, ranging from a one-sample problem with normally distributed observations
Testing Statistical Hypotheses Of Equivalence
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Author : Stefan Wellek
language : en
Publisher: CRC Press
Release Date : 2002-11-12
Testing Statistical Hypotheses Of Equivalence written by Stefan Wellek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-12 with Mathematics categories.
Equivalence testing has grown significantly in importance over the last two decades, especially as its relevance to a variety of applications has become understood. Yet published work on the general methodology remains scattered in specialists' journals, and for the most part, it focuses on the relatively narrow topic of bioequivalence assessment.
Handbook Of Multiple Comparisons
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Author : Xinping Cui
language : en
Publisher: CRC Press
Release Date : 2021-11-17
Handbook Of Multiple Comparisons written by Xinping Cui and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-17 with Mathematics categories.
Written by experts that include originators of some key ideas, chapters in the Handbook of Multiple Testing cover multiple comparison problems big and small, with guidance toward error rate control and insights on how principles developed earlier can be applied to current and emerging problems. Some highlights of the coverages are as follows. Error rate control is useful for controlling the incorrect decision rate. Chapter 1 introduces Tukey's original multiple comparison error rates and point to how they have been applied and adapted to modern multiple comparison problems as discussed in the later chapters. Principles endure. While the closed testing principle is more familiar, Chapter 4 shows the partitioning principle can derive confidence sets for multiple tests, which may become important as the profession goes beyond making decisions based on p-values. Multiple comparisons of treatment efficacy often involve multiple doses and endpoints. Chapter 12 on multiple endpoints explains how different choices of endpoint types lead to different multiplicity adjustment strategies, while Chapter 11 on the MCP-Mod approach is particularly useful for dose-finding. To assess efficacy in clinical trials with multiple doses and multiple endpoints, the reader can see the traditional approach in Chapter 2, the Graphical approach in Chapter 5, and the multivariate approach in Chapter 3. Personalized/precision medicine based on targeted therapies, already a reality, naturally leads to analysis of efficacy in subgroups. Chapter 13 draws attention to subtle logical issues in inferences on subgroups and their mixtures, with a principled solution that resolves these issues. This chapter has implication toward meeting the ICHE9R1 Estimands requirement. Besides the mere multiple testing methodology itself, the handbook also covers related topics like the statistical task of model selection in Chapter 7 or the estimation of the proportion of true null hypotheses (or, in other words, the signal prevalence) in Chapter 8. It also contains decision-theoretic considerations regarding the admissibility of multiple tests in Chapter 6. The issue of selected inference is addressed in Chapter 9. Comparison of responses can involve millions of voxels in medical imaging or SNPs in genome-wide association studies (GWAS). Chapter 14 and Chapter 15 provide state of the art methods for large scale simultaneous inference in these settings.
Statistical Roundtables
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Author : Christine M. Anderson-Cook
language : en
Publisher: Quality Press
Release Date : 2016-04-22
Statistical Roundtables written by Christine M. Anderson-Cook and has been published by Quality Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-22 with Business & Economics categories.
Quality Progress, the flagship journal of ASQ, has been publishing the column Statistics Roundtable since 1999. With over 130 contributions from leading authors in applied statistics, the column has been highly successful and widely read. This book collects 90 of the most interesting and useful articles on some key topics. The editors have constructed this book to be a resource for statisticians and practitioners alike with short, accessible, practical advice in important core areas of statistics from world-renowned experts. This book is intended to be an informative read, with bite-sized columns, as well as a starting point for deeper exploration of key statistical areas. The book contains nine chapters with collections of articles on the following topics: Statistical engineering Data quality and measurement Data collection Key statistical tools Quality control Reliability Multiple response and meta-analysis Applications Communication and training Chapter introductions provide a quick overview of the material contained in the columns of that chapter, as well as complementary articles for that topic that appear elsewhere in the book. Also included at the end of the each chapter introduction is a short list of key references that can provide additional details or examples for material in the topic area.
Encyclopedia Of Medical Decision Making
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Author : Michael W. Kattan
language : en
Publisher: SAGE Publications
Release Date : 2009-08-15
Encyclopedia Of Medical Decision Making written by Michael W. Kattan and has been published by SAGE Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-15 with Medical categories.
Decision making is a critical element in the field of medicine that can lead to life-or-death outcomes, yet it is an element fraught with complex and conflicting variables, diagnostic and therapeutic uncertainties, patient preferences and values, and costs. Together, decisions made by physicians, patients, insurers, and policymakers determine the quality of health care, quality that depends inherently on counterbalancing risks and benefits and competing objectives such as maximizing life expectancy versus optimizing quality of life or quality of care versus economic realities. Broadly speaking, concepts in medical decision making (MDM) may be divided into two major categories: prescriptive and descriptive. Work in the area of prescriptive MDM investigates how medical decisions should be done using complicated analyses and algorithms to determine cost-effectiveness measures, prediction methods, and so on. In contrast, descriptive MDM studies how decisions actually are made involving human judgment, biases, social influences, patient factors, and so on. The Encyclopedia of Medical Decision Making gives a gentle introduction to both categories, revealing how medical and healthcare decisions are actually made—and constrained—and how physician, healthcare management, and patient decision making can be improved to optimize health outcomes. Key Features Discusses very general issues that span many aspects of MDM, including bioethics; health policy and economics; disaster simulation modeling; medical informatics; the psychology of decision making; shared and team medical decision making; social, moral, and religious factors; end-of-life decision making; assessing patient preference and patient adherence; and more Incorporates both quantity and quality of life in optimizing a medical decision Considers characteristics of the decisionmaker and how those characteristics influence their decisions Presents outcome measures to judge the quality or impact of a medical decision Examines some of the more commonly encountered biostatistical methods used in prescriptive decision making Provides utility assessment techniques that facilitate quantitative medical decision making Addresses the many different assumption perspectives the decision maker might choose from when trying to optimize a decision Offers mechanisms for defining MDM algorithms With comprehensive and authoritative coverage by experts in the fields of medicine, decision science and cognitive psychology, and healthcare management, this two-volume Encyclopedia is a must-have resource for any academic library.
Measuring Agreement
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Author : Pankaj K. Choudhary
language : en
Publisher: John Wiley & Sons
Release Date : 2018-01-25
Measuring Agreement written by Pankaj K. Choudhary and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-25 with Medical categories.
Presents statistical methodologies for analyzing common types of data from method comparison experiments and illustrates their applications through detailed case studies Measuring Agreement: Models, Methods, and Applications features statistical evaluation of agreement between two or more methods of measurement of a variable with a primary focus on continuous data. The authors view the analysis of method comparison data as a two-step procedure where an adequate model for the data is found, and then inferential techniques are applied for appropriate functions of parameters of the model. The presentation is accessible to a wide audience and provides the necessary technical details and references. In addition, the authors present chapter-length explorations of data from paired measurements designs, repeated measurements designs, and multiple methods; data with covariates; and heteroscedastic, longitudinal, and categorical data. The book also: • Strikes a balance between theory and applications • Presents parametric as well as nonparametric methodologies • Provides a concise introduction to Cohen’s kappa coefficient and other measures of agreement for binary and categorical data • Discusses sample size determination for trials on measuring agreement • Contains real-world case studies and exercises throughout • Provides a supplemental website containing the related datasets and R code Measuring Agreement: Models, Methods, and Applications is a resource for statisticians and biostatisticians engaged in data analysis, consultancy, and methodological research. It is a reference for clinical chemists, ecologists, and biomedical and other scientists who deal with development and validation of measurement methods. This book can also serve as a graduate-level text for students in statistics and biostatistics.
Multivariate Exponential Families A Concise Guide To Statistical Inference
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Author : Stefan Bedbur
language : en
Publisher: Springer Nature
Release Date : 2021-10-07
Multivariate Exponential Families A Concise Guide To Statistical Inference written by Stefan Bedbur and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-07 with Mathematics categories.
This book provides a concise introduction to exponential families. Parametric families of probability distributions and their properties are extensively studied in the literature on statistical modeling and inference. Exponential families of distributions comprise density functions of a particular form, which enables general assertions and leads to nice features. With a focus on parameter estimation and hypotheses testing, the text introduces the reader to distributional and statistical properties of multivariate and multiparameter exponential families along with a variety of detailed examples. The material is widely self-contained and written in a mathematical setting. It may serve both as a concise, mathematically rigorous course on exponential families in a systematic structure and as an introduction to Mathematical Statistics restricted to the use of exponential families.
Recent Advancements In Structural Equation Modeling Sem From Both Methodological And Application Perspectives
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Author : Oi-Man Kwok
language : en
Publisher: Frontiers Media SA
Release Date : 2019-02-08
Recent Advancements In Structural Equation Modeling Sem From Both Methodological And Application Perspectives written by Oi-Man Kwok and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-08 with categories.
Structural equation modeling (SEM) is becoming the central and one of the most popular analytical tools in the social sciences. Many classical and modern statistical techniques such as regression analysis, path analysis, confirmatory factor analysis, and models with both measurement and structural components have been shown to fall under the umbrella of SEM. Thus, the flexibility of SEM makes it applicable to many research designs, including experimental and non-experimental data, cross-sectional and longitudinal data, and multiple-group and multilevel data. In this eBook, you will find 19 cutting-edge papers from the Research Topic: Recent Advancements in Structural Equation Modeling (SEM). These 19 papers cover a wide variety of topics related to SEM, including: (a) analysis of different types of data (from cross-sectional data with floor effects to complex survey data and longitudinal data); (b) measurement-related issues (from the development of new scale to the evaluation of person fit and new ways to test measurement invariance); and (c) technical advancement and software development. We hope that the readers will gain new perspectives and be able to apply some of the new techniques and models discussed in these 19 papers.
Virtual And Augmented Reality Concepts Methodologies Tools And Applications
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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2018-03-02
Virtual And Augmented Reality Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-02 with Computers categories.
Virtual and augmented reality is the next frontier of technological innovation. As technology exponentially evolves, so do the ways in which humans interact and depend upon it. Virtual and Augmented Reality: Concepts, Methodologies, Tools, and Applications is a comprehensive reference source for the latest scholarly material on the trends, techniques, and uses of virtual and augmented reality in various fields, and examines the benefits and challenges of these developments. Highlighting a range of pertinent topics, such as human-computer interaction, digital self-identity, and virtual reconstruction, this multi-volume book is ideally designed for researchers, academics, professionals, theorists, students, and practitioners interested in emerging technology applications across the digital plane.
Engineering Biostatistics
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Author : Brani Vidakovic
language : en
Publisher: John Wiley & Sons
Release Date : 2017-11-06
Engineering Biostatistics written by Brani Vidakovic and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-06 with Mathematics categories.
Provides a one-stop resource for engineers learning biostatistics using MATLAB® and WinBUGS Through its scope and depth of coverage, this book addresses the needs of the vibrant and rapidly growing bio-oriented engineering fields while implementing software packages that are familiar to engineers. The book is heavily oriented to computation and hands-on approaches so readers understand each step of the programming. Another dimension of this book is in parallel coverage of both Bayesian and frequentist approaches to statistical inference. It avoids taking sides on the classical vs. Bayesian paradigms, and many examples in this book are solved using both methods. The results are then compared and commented upon. Readers have the choice of MATLAB® for classical data analysis and WinBUGS/OpenBUGS for Bayesian data analysis. Every chapter starts with a box highlighting what is covered in that chapter and ends with exercises, a list of software scripts, datasets, and references. Engineering Biostatistics: An Introduction using MATLAB® and WinBUGS also includes: parallel coverage of classical and Bayesian approaches, where appropriate substantial coverage of Bayesian approaches to statistical inference material that has been classroom-tested in an introductory statistics course in bioengineering over several years exercises at the end of each chapter and an accompanying website with full solutions and hints to some exercises, as well as additional materials and examples Engineering Biostatistics: An Introduction using MATLAB® and WinBUGS can serve as a textbook for introductory-to-intermediate applied statistics courses, as well as a useful reference for engineers interested in biostatistical approaches.