The 3 Dimensional Atlas Of The Marmoset Brain

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The 3 Dimensional Atlas Of The Marmoset Brain

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Author : Atsushi Iriki
language : en
Publisher: Springer
Release Date : 2018-12-12

The 3 Dimensional Atlas Of The Marmoset Brain written by Atsushi Iriki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-12 with Medical categories.

This book provides accurate, comprehensive, and convenient reference for usages of the “freely rotatable three dimensional combined Nissl-stained and MRI digital data of the marmoset brain”. The key features of the original 3D digital data and of this atlas are: 1. The original digital datasets are freely rotatable in three dimensions, thus expected to be useful for any disciplines and anatomical interest, using any coordinate system, 2. Combined Nissl stained and MRI images are obtained from the same marmoset, to allow cross-modality matched references for multiple usages, 3. 86 Horizontal Series of Images with Neurosurgical Plane (based on the actual data), with more accuracy and resolution (Chapter 2) than the web-based digital images, 4. 32 Coronal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 3), 5. 10 Parasagittal Series of Images with Neurosurgical Plane (reproduced from the brain model) (Chapter 4), 6. 3 Omnidirectionally Sliceable Planes (reproduced from the brain model) (Chapter 5), 7. In order to provide higher resolution structures to match systematic accuracy for supplementation of the digital data on the website, additional information are included. They are: 1) Nomenclature, 2) List of Brain Structures in Hierarchical Order, 3) Index of Abbreviations, together with 143 useful Bibliographic References list as of 2016, 8. Horsley-Clarke’s stereotaxic coordinates were adopted in the present atlas.

Innovative Imaging Techniques In Preclinical Models Of Neurodegenerative Diseases

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Author : Rodolfo Gabriel Gatto
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10

Innovative Imaging Techniques In Preclinical Models Of Neurodegenerative Diseases written by Rodolfo Gabriel Gatto and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Science categories.

The Evolutionary Roots Of Human Brain Diseases

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Author : Nico J. Diederich
language : en
Publisher: Oxford University Press
Release Date : 2024

The Evolutionary Roots Of Human Brain Diseases written by Nico J. Diederich and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024 with Medical categories.

"Traditionally, studies and textbooks in Neurology or Psychiatry, as well as allied disciplines, deal with proximate causes of diseases and therapies, but remain mute or minimally interested in their ultimate causes including the phylogeny and adaptive significance of disease manifestations. Yet, as clinicians or basic researchers, we are conscious of potential evolutionary roots of neurological and psychiatric symptoms, often offering a rudimentary explanation but never delving deeply into the current role of evolutionary science as it relates to health and disease. We may miss appreciation of the role of adaptive properties, evolutionarily based neuronal circuitries, unbalanced cellular energy demands, and the potential health consequences of residual syndromic behaviors that were possibly useful in early times of human development, but presently are obsolete and pathological. The problem is amplified, because there is often no interdisciplinary dialogue between anthropology and evolutionary biology on one side and clinical sciences on the other side. However, the evolutionary tracing back of disease pathways may disclose unexpected insights and trigger the design of innovative research as well as propel the development of new therapeutic interventions. There could also be a better apprehension of compensatory behaviors, both at the cellular level as well as the systemic the behavioural levels, that could be the expected fruits of such collaborations. So far scientists fall short in modeling the complexity of human (social) life, human language, or manual dexterity, and mental or emotional behaviors that typify human neurological or psychological function and dysfunction. Finally, there remain obstacles in the form of poor animal modeling for human brain diseases and for human longevity. The present book aims to fill these gaps by presenting an evolutionary view of neurological and psychiatric conditions that is meant to complement and enrich existing medical perspectives"--

Care Use And Welfare Of Marmosets As Animal Models For Gene Editing Based Biomedical Research

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-08-26

Care Use And Welfare Of Marmosets As Animal Models For Gene Editing Based Biomedical Research written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-26 with Science categories.

The marmoset, a type of small monkey native to South America, is a research model of increasing importance for biomedical research in the United States and globally. Marmosets offer a range of advantages as animal models in neuroscience, aging, infectious diseases, and other fields of study. They may be particularly useful for the development of new disease models using genetic engineering and assisted reproductive technologies. However, concerns have been voiced with respect to the development of new marmoset-based models of disease, ethical considerations for their use, the supply of marmosets available for research, and gaps in guidance for their care and management. To explore and address these concerns, the Roundtable on Science and Welfare in Laboratory Animal Use hosted a public workshop on October 22-23, 2018, in Washington, DC. The workshop focused on the availability of marmosets in the United States and abroad; animal welfare and ethical considerations stemming from the use of wildtype and genetically modified marmosets; and standards of housing and care, dietary needs, and feeding requirements for marmosets in captivity. This publication summarizes the presentations and discussions from the workshop.

Animal Creativity And Innovation

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Author :
language : en
Publisher: Academic Press
Release Date : 2015-10-29

Animal Creativity And Innovation written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-29 with Psychology categories.

Animal Creativity and Innovation explores theories and research on animal innovation and creativity, comparing and contrasting it with theory and research on human creativity and innovation. In doing so, it encompasses findings from psychology, biology, neuroscience, engineering, business, ecology, and education. The book includes examples of animal innovation in parrots, dogs, marine mammals, insects, and primates, exploring parallels from creative play in children. The book defines creativity, differentiating it from play, and looks at evolutionary models and neurological constructs. The book further explores applied aspects of animal innovation and creativity including tool use and group dynamics, as well as barriers to creativity. The final chapters look into how creative behavior may be taught or trained. Each chapter is followed by a commentary for integration of thoughts and ideas between animal and human research, behavioral and cognitive research, and theory and observation in real life. - Compares theory and research on animal and human creativity - Defines and differentiates creativity from play - Reviews applied creativity in tool use and social dynamics - Includes examples of animal creativity in multiple species

The Common Marmoset In Captivity And Biomedical Research

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Author : Robert P. Marini
language : en
Publisher: Academic Press
Release Date : 2018-11-19

The Common Marmoset In Captivity And Biomedical Research written by Robert P. Marini and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-19 with Science categories.

The Common Marmoset in Captivity and Biomedical Research is the first text dedicated exclusively to this species,filling an urgent need for an encyclopedic compilation of the existing information. Sponsored by the AmericanCollege of Laboratory Animal Medicine as part of its authoritative Blue Book series, the book covers the biology,management, diseases, and clinical and research applications of this important species. The common marmoset(Callithrix jacchus) has come of age in the scientific community as a behaviorally complex, cognitively advanced,small, prolific, and easily maintained nonhuman primate with many of the advantages of larger animals, such asmacaques, but without the attendant physical and zoonotic risks. Marmosets are currently being used in diverse areas of inquiry, including vision and auditory research, infectious disease, cognitive neuroscience, behavior, reproductive biology, toxicology and drug development, and aging. Themarmoset genome has been sequenced and there is currently an intensive effort to apply gene editing technologies to the species. The creation of transgenic marmosets will provide researchers with a small nonhuman primatemodel to study a number of poorly understood disorders, like autism. - Presents a complete view of the marmoset, covering their biology and management, diseases and clinical applications, and research applications - Includes contributions from renowned and international authors and editors - Provides the first authoritative and comprehensive treatment of marmosets in biomedical research as part of the ACLAM Series

Stereotaxic And Chemoarchitectural Atlas Of The Brain Of The Common Marmoset Callithrix Jacchus

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Author : Craig D. Hardman
language : en
Publisher: CRC Press
Release Date : 2012-01-24

Stereotaxic And Chemoarchitectural Atlas Of The Brain Of The Common Marmoset Callithrix Jacchus written by Craig D. Hardman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-24 with Medical categories.

Developing better therapies for neurological conditions such as Parkinson’s and Alzheimer’s diseases remains an enduring problem for 21st century medicine. The testing of novel therapies will continue to require a robust experimental animal model. The marmoset is an ideal animal model for modern neurological research because of the species’ convenient body size, ease of handling, and the fundamental similarity of its neuroanatomy to the human brain. The Stereotaxic and Chemoarchitectural Atlas of the Brain of the Common Marmoset (Callithrix jacchus) is the most detailed atlas of the marmoset brain available. An essential tool for researchers developing more effective therapies for disabling and debilitating neurological disorders, the book contains: Fully delineated, high-quality (400x magnification) images of Nissl-stained, acetylcholinesterase histochemically-stained and parvalbumin, calbindin and neurofilament immunohistochemically-stained coronal and sagittal sections, as well as structural magnetic resonance images (MRI) for direct comparisons Line diagrams with delineations of all cortical and subcortical structures, with grid overlays so the precise position of each structure can be located stereotaxically relative to the interaural line and infraorbital margin Quantitative data regarding volume and cell number of many of the structures delineated in the atlas, regularly updated on an accompanying website Standard nomenclature widely used in the Paxinos group of atlases, allowing users to compare and contrast homologous nuclei in different species using the major available atlases The book combines modern imaging (MRI) with an accurate stereotaxic and chemoarchitectonic section atlas, making the fullest use of available technologies. The downloadable resources include all the images in full color. Designed by publishing neuroanatomists, this book/downloadable resources will be a cornerstone in marmoset brain research for years to come.

Mri Dti Atlas Of The Human Brainstem In Transverse And Sagittal Planes

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Author : George Paxinos
language : en
Publisher: Elsevier
Release Date : 2023-03-02

Mri Dti Atlas Of The Human Brainstem In Transverse And Sagittal Planes written by George Paxinos and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-02 with Medical categories.

**Selected for Doody's Core Titles® 2024 in Neuroscience**MRI/DTI Atlas of the Human Brainstem in Transverse and Sagittal Planes presents a detailed view of the human brainstem in DTI/MRI. It is the first ever MRI or histological atlas to present detailed diagrams of sagittal views of the brainstem. Presenting data of unprecedented quality, images are juxtaposed with detailed diagrams in the transverse and sagittal planes. The atlas features a 50 micron resolution for the GRE and 200 microns for the FAC and DWI, 8000 times higher than that seen in a clinical MRI and 1000 times higher than that seen in a clinical DTI scan, all based on one brain. This atlas is important for neuroscientists, neurosurgeons, pathologists, anatomists, neurophysiologists, radiologists, radiotherapists (e.g., for cyberknife guidance), and graduate students in neuroscience. - Presents the first ever detailed MRI-DTI atlas on the human brainstem - Discusses primary data to help researchers identify brainstem structures in their own preparations from neuroanatomical, physiological, neuropharmacological and gene expression studies - Accompanies the gold standard reference on the neuroanatomy of the human nervous system for neuroscientists and experimental psychologists - Includes the Expert Consult eBook version that is compatible with PC, Mac and most mobile devices and eReaders, thus allowing readers to browse, search and interact with content

Mri Dti Atlas Of The Rat Brain

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Author : George Paxinos
language : en
Publisher: Academic Press
Release Date : 2015-05-28

Mri Dti Atlas Of The Rat Brain written by George Paxinos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-28 with Science categories.

MRI/DTI Atlas of the Rat Brain offers two major enhancements when compared with earlier attempts to make MRI/DTI rat brain atlases. First, the spatial resolution at 25μm is considerably higher than previous data published. Secondly, the comprehensive set of MRI/DTI contrasts provided has enabled the authors to identify more than 80% of structures identified in The Rat Brain in Stereotaxic Coordinates. - Ninety-six coronal levels from the olfactory bulb to the pyramidal decussation are depicted - Delineations primarily made on the basis of direct observations on the MRI contrasts - Each of the 96 open book pages displays four items— top left, the directionally colored fractional anisotropy image derived from DTI (DTI - FAC); top right, the diffusion-weighted image (DWI); bottom left, the gradient recalled echo (GRE); and bottom right, a diagrammatic synthesis of the information derived from these three images plus two additional images, which are not displayed (ARDC and RD). This is repeated for 96 coronal levels, which makes the levels 250 μm apart - The FAC images are shown in full color - The orientation of sections corresponds to that in Paxinos and Watson's The Rat Brain in Stereotaxic Coordinates, 7th Edition (2014) - The images have been obtained from 3D isotropic population averages (number of rats=5). All abbreviations of structure names are identical to the Paxinos & Watson histologic atlas

Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 4 Toxicologic Pathology Of Organ Systems

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Author : Wanda M. Haschek
language : en
Publisher: Elsevier
Release Date : 2024-03-05

Haschek And Rousseaux S Handbook Of Toxicologic Pathology Volume 4 Toxicologic Pathology Of Organ Systems written by Wanda M. Haschek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-05 with Medical categories.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume Four: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. Organ systems covered include cardiac, vascular and skeletal muscle systems and the endocrine, respiratory, reproductive, digestive and nervous systems. Completely revised with a new olfactory chapter, this new release is an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. - Presents updated chapters on systems toxicologic pathology, including new chapter on olfactory - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions to highlight difficult concepts with clear illustrations