The Analysis Of Human Haemoglobin Variants Using Mass Spectrometry
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The Analysis Of Human Haemoglobin Variants Using Mass Spectrometry
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Author : Brian N. Green
language : en
Publisher:
Release Date : 2021
The Analysis Of Human Haemoglobin Variants Using Mass Spectrometry written by Brian N. Green and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Hemoglobin categories.
Disorders Of Hemoglobin
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Author : Martin H. Steinberg
language : en
Publisher: Cambridge University Press
Release Date : 2009-08-17
Disorders Of Hemoglobin written by Martin H. Steinberg and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-17 with Medical categories.
Completely revised new edition of the definitive reference on disorders of hemoglobin.
Dried Blood Spots
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Author : Wenkui Li
language : en
Publisher: John Wiley & Sons
Release Date : 2014-05-21
Dried Blood Spots written by Wenkui Li and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-21 with Science categories.
An informative and comprehensive book on the applications andtechniques of dried blood spot sampling Dried blood spot (DBS) sampling involves the collection of asmall volume of blood, via a simple prick or other means, from astudy subject onto a cellulose or polymer paper card, which isfollowed by drying and transfer to the laboratory for analysis. Formany years, this method of blood sample collection has beenextensively utilized in some important areas of human healthcare(for example, newborn screening for inherited metabolic disordersand HIV-related epidemiological studies). Because of its advantagesover conventional blood, plasma, or serum sample collection, DBSsampling has been valued by the pharmaceutical industry in drugresearch and development. Dried Blood Spots: Applications and Techniques featurescontributions from an international team of leading scientists inthe field. Their contributions present a unique resource on thehistory, principles, procedures, methodologies, applications, andemerging technologies related to DBS. Presented in three parts, the book thoroughly examines: Applications of DBS sampling and associated procedures andmethodologies in various human healthcare studies Applications and perspectives of DBS sampling in drug researchand development, and therapeutic drug monitoring New technologies and emerging applications related to DBSsampling and analysis Dried Blood Spots: Applications and Techniques is avaluable working guide for researchers, professionals, and studentsin healthcare, medical science, diagnostics, clinical chemistry,and pharmaceuticals, etc.
Red Cell Metabolism
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Author : Ernest Beutler
language : en
Publisher:
Release Date : 1975
Red Cell Metabolism written by Ernest Beutler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medical categories.
Variant Haemoglobins
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Author : Barbara J. Bain
language : en
Publisher: John Wiley & Sons
Release Date : 2011-06-28
Variant Haemoglobins written by Barbara J. Bain and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
Variant Haemoglobins – A Guide to Identification is based on the premise that any single diagnostic technique offers only a very provisional identification of a variant haemoglobin. In routine diagnostic practice two techniques are needed as a minimum, with the results being interpreted in the light of the clinical details, blood count, blood film and ethnic origin. This book covers 150 normal and variant haemoglobins that have been studied and carefully documented. Variant Haemoglobins has four introductory chapters followed by an invaluable atlas. The introductory chapters cover the genetics of haemoglobin synthesis the principles of tests employed for identification common haemoglobins of major clinical or diagnostic importance thalassaemias and related conditions The atlas section comprises 170 full colour pages in which each variant haemoglobin or combination of haemoglobins is illustrated by cellulose acetate electrophoresis at alkaline pH, agarose gel electrophoresis at acid pH, isoelectric focusing and one or more HPLC traces. For ease of reference, the atlas pages are arranged according to the retention time of each haemoglobin on HPLC, this becoming increasingly the primary technique employed in haemoglobin identification. Bringing a mix of necessary scientific expertise and clinical knowledge, each author has more than 30 years experience in the diagnosis of variant haemoglobins. Providing otherwise unavailable information, this unique and practical guide is illustrated with over 700 high quality colour digital images plus flow charts and line diagrams covers common and important haemoglobin variants, in addition to many rarer ones is an essential reference source for diagnosis in the haematology laboratory A remarkably useful book, Variant Haemoglobins will be valuable for haematopathologists, clinical and laboratory haematologists in practice and in training and all laboratory staff involved in haemoglobinopathy diagnosis.
Mass Spectrometry In The Biological Sciences A Tutorial
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Author : M.L Gross
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mass Spectrometry In The Biological Sciences A Tutorial written by M.L Gross and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was given new meaning because important structural information for biomolecules could now be produced for ions introduced by FAB into the tandem instrument. The evolution of MS/MS continues today with the development of ion traps, time-of-flight, and sector instruments equipped with array detection.
Advances In Clinical Chemistry
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Author : Gregory S. Makowski
language : en
Publisher: Academic Press
Release Date : 2012-03-30
Advances In Clinical Chemistry written by Gregory S. Makowski and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-30 with Medical categories.
Volume 57 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology. Written by authors representing the diverse field of clinical chemistry and diagnostics, reviews in Advances in Clinical Chemistry cover a range of cutting-eduge research ranging from basic biochemical exploration to microarray technology
Mass Spectrometry Of Peptides
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Author : Dominic M. Desiderio
language : en
Publisher: CRC Press
Release Date : 1990-11-14
Mass Spectrometry Of Peptides written by Dominic M. Desiderio and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990-11-14 with Science categories.
The purpose of this book is to collect into one volume the research done on the mass spectrometry of peptides. It balances a range of topics including theory, instrumentation, analytical techniques, and biological applications. The scope of the work contains three major sections: ionization methods, instrumental developments, and analysis of peptides. It describes 252Cf plasma desorption and laser-induced multiphoton ionization methodology. This exciting resource covers many new areas, including continuous flow FAB, quantification of human neuropeptides, and peptide mapping. It also discusses Q-FTMS, cross-links, and metal ions.
Vertebrate And Invertebrate Respiratory Proteins Lipoproteins And Other Body Fluid Proteins
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Author : Ulrich Hoeger
language : en
Publisher: Springer Nature
Release Date : 2020-03-18
Vertebrate And Invertebrate Respiratory Proteins Lipoproteins And Other Body Fluid Proteins written by Ulrich Hoeger and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-18 with Science categories.
This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.
Electrophoresis
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Author : Budin Michov
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-09-07
Electrophoresis written by Budin Michov and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-07 with Science categories.
Electrophoresis is a straightforward but informative analytical method used in biochemistry, biology and medicine. This book combines a detailed discussion of theory and technical application with an elaborate section on troubleshooting and problem solving in electrophoresis. Therefore the book is an important guide for both students and scientists.