The Antibiotic Era
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The Antibiotic Era
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Author : Scott H. Podolsky
language : en
Publisher: JHU Press
Release Date : 2015-01-15
The Antibiotic Era written by Scott H. Podolsky and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-15 with Medical categories.
A compelling analysis of nearly seven decades of antibiotic reform, framing our current efforts to stave off a post-antibiotic era. Winner of the CHOICE Outstanding Academic Title of the Choice ACRL In The Antibiotic Era, physician-historian Scott H. Podolsky narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed. This sweeping chronicle reveals the struggles faced by crusading reformers from the 1940s onward as they advocated for a rational therapeutics at the crowded intersection of bugs and drugs, patients and doctors, industry and medical academia, and government and the media. During the post–World War II “wonder drug” revolution, antibiotics were viewed as a panacea for mastering infectious disease. But from the beginning, critics raised concerns about irrational usage and overprescription. The first generation of antibiotic reformers focused on regulating the drug industry. The reforms they set in motion included the adoption of controlled clinical trials as the ultimate arbiters of therapeutic efficacy, the passage of the Kefauver-Harris amendments mandating proof of drug efficacy via well-controlled studies, and the empowering of the Food and Drug Administration to remove inefficacious drugs from the market. Despite such victories, no entity was empowered to rein in physicians who inappropriately prescribed, or overly prescribed, approved drugs. Now, in an era of emerging bugs and receding drugs, discussions of antibiotic resistance focus on the need to develop novel antibiotics and the need for more appropriate prescription practices in the face of pharmaceutical marketing, pressure from patients, and the structural constraints that impede rational delivery of antibiotics worldwide. Concerns about the enduring utility of antibiotics—indeed, about a post-antibiotic era—are widespread, as evidenced by reports from the Centers for Disease Control and Prevention, academia, and popular media alike. Only by understanding the historical forces that have shaped our current situation, Podolsky argues, can we properly understand and frame our choices moving forward.
The Antibiotic Era
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Author : Scott H. Podolsky
language : en
Publisher: JHU Press
Release Date : 2015-01-15
The Antibiotic Era written by Scott H. Podolsky and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-15 with Medical categories.
During the post-World War II "wonder drug" revolution, antibiotics were viewed as a panacea for mastering infectious disease. This book narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed
Launching The Antibiotic Era
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Author : Carol L. Moberg
language : en
Publisher: Rockefeller Univ. Press
Release Date : 1990
Launching The Antibiotic Era written by Carol L. Moberg and has been published by Rockefeller Univ. Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
The End Of An Antibiotic Era
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Author : Rinke van den Brink
language : en
Publisher: Springer Nature
Release Date : 2021-05-13
The End Of An Antibiotic Era written by Rinke van den Brink and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-13 with Medical categories.
In this monograph, journalist Rinke van den Brink takes a closer look at the limitations and risks of today’s antibiotic use. Though all developed societies have grown accustomed to successfully treating bacterial infections with these wonder drugs, the author focuses on the increasing number of antibiotic-resistant infections. By examining recent mass outbreaks, readers will gain a better understanding of the global impact of antimicrobial resistance – one of the most serious public health threats today. Following this somewhat disquieting review of the status quo, interviews with a number of specialists provide an outlook on possible solutions. In a world that is more connected than ever, partnerships between different healthcare systems are becoming all the more important. Rinke van den Brink uses the example of a border-spanning collaboration between the Netherlands and Germany to demonstrate how effective lines of communication can be established. The book offers a wealth of useful background information for healthcare personnel. Not only does it share insights into the functional microbe-antibiotic relationship; it also discusses how clinics can effectively address outbreaks, helping readers to learn from past experiences and develop effective new strategies.
Living In The Post Antibiotic Era
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Author : D. W. Graeme
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2018-03-27
Living In The Post Antibiotic Era written by D. W. Graeme and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-27 with categories.
Discover how we are now living in the Post Antibiotic Era... and what we need to do about antibiotic resistance, if we want to survive. Like it or not, we are now facing what was once termed in a popular hit song, "(On) The Eve of Destruction." Unfortunately, it will be a destruction of our own making. We have caused it all by creating and over-using / over-prescribing antibiotics. This book is for your education, to arm you with the key information to keep you safe, as to what we are facing at this moment in time. This short but concise book will show you what you, as an individual, need to do to protect yourself and your family now, and in the future! When you purchase 'Living In The Post Antibiotic Era, What Will We Do Now To Survive?', you will discover: How antibiotics got here in the first place Where are we today and how this "Miracle" betrayed us What exactly are we fighting How antibiotics work The origins of the antibiotic Why it's so hard to control outbreaks The Antibiotics "Most Not-Wanted" List How an ounce of preventation can make all the difference Where do we go from here While it is impossible to fit all of the information on the Antibiotic dilemna we have created, I have hand choosed the information I know from my own experience, insights from doctors, and thorough research, to bring you this interesting and informative read. It is my hope, that this book will help you make better decisions and keep you safe in the coming years, as we hit the proverbial "Tipping" point of medicine. If you are want to make the best decisions in the coming years, when it comes to antibiotics, then this book is for you. Download this book today and help your friends and family stay safe.
Antibiotic Policies
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Author : Ian M. Gould
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-25
Antibiotic Policies written by Ian M. Gould and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-25 with Medical categories.
The first book was on "Theory and Practice" of antibiotic stewardship in its broadest sense -the how to do it and the do's and don’ts. The second, on "Controlling resistance" was very much on the relationships between use and resistance and beginning to home in on the hospital as the main generator of resistance, but mainly looking at it from a disease/clinical perspective. The last 3 chapters on MRSA, ended where the 3rd book will take off. "Controlling HAI " will concentrate on specific MDR organisms highlighting their roles in the current pandemic of HAI and emphasizing that the big issue is not so much infection control but antibiotic control, in the same way that antibiotic over-reliance/ over-use has caused the problem in the first place. Up 'till now the emphasis for controlling MRSA, C diff and all the other MDROs has very much been on IC, which clearly isn't working. This book will gather all the evidence for the increasingly popular view that much more must be done in the area of antibiotic policies/ stewardship, especially when we are in danger of a "post antibiotic" era, due to a real shortage of new agents in the pipeline.
Streptomycin
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Author : Rutgers Research and Educational Foundation, New Brunswick, N.J.
language : en
Publisher:
Release Date : 1964
Streptomycin written by Rutgers Research and Educational Foundation, New Brunswick, N.J. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Streptomycin categories.
How Antibiotics Changed The World
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Author : Toney Allman
language : en
Publisher: Referencepoint Press
Release Date : 2018-08
How Antibiotics Changed The World written by Toney Allman and has been published by Referencepoint Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08 with Antibiotics categories.
Antibiotics revolutionized the practice of medicine. Deadly diseases and infections became easily curable and untold millions are alive because of antibiotics. The ways industry, agriculture, and medical research function and have developed have been transformed as well. Nevertheless, the bacterial world's response to antibiotics is as dramatic as the results of the human discovery. The rise of drug resistant bacteria is challenging the medical world as never before and threatening the advent of a post-antibiotic era that scientists are determined to forestall.
Bacterial Resistance To Antibiotics
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Author : Boyan B. Bonev
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-14
Bacterial Resistance To Antibiotics written by Boyan B. Bonev and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-14 with Science categories.
AN AUTHORITATIVE SURVEY OF CURRENT RESEARCH INTO CLINICALLY USEFUL CONVENTIONAL AND NONCONVENTIONAL ANTIBIOTIC THERAPEUTICS Pharmaceutically-active antibiotics revolutionized the treatment of infectious diseases, leading to decreased mortality and increased life expectancy. However, recent years have seen an alarming rise in the number and frequency of antibiotic-resistant "Superbugs." The Centers for Disease Control and Prevention (CDC) estimates that over two million antibiotic-resistant infections occur in the United States annually, resulting in approximately 23,000 deaths. Despite the danger to public health, a minimal number of new antibiotic drugs are currently in development or in clinical trials by major pharmaceutical companies. To prevent reverting back to the pre-antibiotic era—when diseases caused by parasites or infections were virtually untreatable and frequently resulted in death—new and innovative approaches are needed to combat the increasing resistance of pathogenic bacteria to antibiotics. Bacterial Resistance to Antibiotics – From Molecules to Man examines the current state and future direction of research into developing clinically-useful next-generation novel antibiotics. An internationally-recognized team of experts cover topics including glycopeptide antibiotic resistance, anti-tuberculosis agents, anti-virulence therapies, tetracyclines, the molecular and structural determinants of resistance, and more. Presents a multidisciplinary approach for the optimization of novel antibiotics for maximum potency, minimal toxicity, and appropriated degradability Highlights critical aspects that may relieve the problematic medical situation of antibiotic resistance Includes an overview of the genetic and molecular mechanisms of antibiotic resistance Addresses contemporary issues of global public health and longevity Includes full references, author remarks, and color illustrations, graphs, and charts Bacterial Resistance to Antibiotics – From Molecules to Man is a valuable source of up-to-date information for medical practitioners, researchers, academics, and professionals in public health, pharmaceuticals, microbiology, and related fields.
The Tetracyclines
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Author : Joseph J. Hlavka
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Tetracyclines written by Joseph J. Hlavka and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The history of antibiotics may weIl have begun with the ancient Sudanese-Nubian civilization (see Chapter 1, "Historical Introduction"), but this volume reflects a more contemporary appraisal of the antibiotic era. We have compiled a comprehensive review of the tetracyclines which includes all the major sub divisions of these chemically important and clinically useful antibiotics. There can be little doubt about the contribution of antibiotics to both the increase in human life span and the alleviation of much human suffering. The tetracyclines are still playing an important role in these areas and will continue to do so in the foreseeable future. We hope this volume will be an important contribution to a better under standing of the chemistry, biochemistry, and medical aspects of tetracycline antibiotics. We are indebted to the individual authors who have given so much of their time and effort in the preparation of the chapters. Pearl River, NY J OSEPH J. HLA VKA Ocean Gate, NJ JAMES H. BOOTHE Contents CHAPTER 1 Historical Introduction. J. H. BOOTHE and J. J. HLAVKA References. 3 CHAPTER 2 Fermentation and Mutational Development of the Tetracyclines J. J. GOODMAN A. Introduction 5 B. The Producing Microorganisms . 6 I. Morphology and Ultrastructure 6 11. Mutation and Strain Selection 8 111. Cosynthesis. 13 The Fermentation Process 14 C. I. Inoculum 14 11. Contamination 16 Complex Media. 18 111. IV. Synthetic Media. 27 V. Stimulators and Inhibitors 30 Directed Fermentations 32 VI.