Launching The Antibiotic Era
DOWNLOAD eBooks
Download Launching The Antibiotic Era PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Launching The Antibiotic Era book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Launching The Antibiotic Era
DOWNLOAD eBooks
Author : Carol L. Moberg
language : en
Publisher: Rockefeller Univ. Press
Release Date : 1990
Launching The Antibiotic Era written by Carol L. Moberg and has been published by Rockefeller Univ. Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Medical categories.
The Antibiotic Era
DOWNLOAD eBooks
Author : Scott H. Podolsky
language : en
Publisher: JHU Press
Release Date : 2015-01-15
The Antibiotic Era written by Scott H. Podolsky and has been published by JHU Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-15 with Medical categories.
A compelling analysis of nearly seven decades of antibiotic reform, framing our current efforts to stave off a post-antibiotic era. Winner of the CHOICE Outstanding Academic Title of the Choice ACRL In The Antibiotic Era, physician-historian Scott H. Podolsky narrates the far-reaching history of antibiotics, focusing particularly on reform efforts that attempted to fundamentally change how antibiotics are developed and prescribed. This sweeping chronicle reveals the struggles faced by crusading reformers from the 1940s onward as they advocated for a rational therapeutics at the crowded intersection of bugs and drugs, patients and doctors, industry and medical academia, and government and the media. During the post–World War II “wonder drug” revolution, antibiotics were viewed as a panacea for mastering infectious disease. But from the beginning, critics raised concerns about irrational usage and overprescription. The first generation of antibiotic reformers focused on regulating the drug industry. The reforms they set in motion included the adoption of controlled clinical trials as the ultimate arbiters of therapeutic efficacy, the passage of the Kefauver-Harris amendments mandating proof of drug efficacy via well-controlled studies, and the empowering of the Food and Drug Administration to remove inefficacious drugs from the market. Despite such victories, no entity was empowered to rein in physicians who inappropriately prescribed, or overly prescribed, approved drugs. Now, in an era of emerging bugs and receding drugs, discussions of antibiotic resistance focus on the need to develop novel antibiotics and the need for more appropriate prescription practices in the face of pharmaceutical marketing, pressure from patients, and the structural constraints that impede rational delivery of antibiotics worldwide. Concerns about the enduring utility of antibiotics—indeed, about a post-antibiotic era—are widespread, as evidenced by reports from the Centers for Disease Control and Prevention, academia, and popular media alike. Only by understanding the historical forces that have shaped our current situation, Podolsky argues, can we properly understand and frame our choices moving forward.
The End Of An Antibiotic Era
DOWNLOAD eBooks
Author : Rinke van den Brink
language : en
Publisher:
Release Date : 2021
The End Of An Antibiotic Era written by Rinke van den Brink and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
In this monograph, journalist Rinke van den Brink takes a closer look at the limitations and risks of today's antibiotic use. Though all developed societies have grown accustomed to successfully treating bacterial infections with these wonder drugs, the author focuses on the increasing number of antibiotic-resistant infections. By examining recent mass outbreaks, readers will gain a better understanding of the global impact of antimicrobial resistance - one of the most serious public health threats today. Following this somewhat disquieting review of the status quo, interviews with a number of specialists provide an outlook on possible solutions. In a world that is more connected than ever, partnerships between different healthcare systems are becoming all the more important. Rinke van den Brink uses the example of a border-spanning collaboration between the Netherlands and Germany to demonstrate how effective lines of communication can be established. The book offers a wealth of useful background information for healthcare personnel. Not only does it share insights into the functional microbe-antibiotic relationship; it also discusses how clinics can effectively address outbreaks, helping readers to learn from past experiences and develop effective new strategies.
How Antibiotics Changed The World
DOWNLOAD eBooks
Author : Toney Allman
language : en
Publisher: Referencepoint Press
Release Date : 2018-08
How Antibiotics Changed The World written by Toney Allman and has been published by Referencepoint Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08 with Antibiotics categories.
Antibiotics revolutionized the practice of medicine. Deadly diseases and infections became easily curable and untold millions are alive because of antibiotics. The ways industry, agriculture, and medical research function and have developed have been transformed as well. Nevertheless, the bacterial world's response to antibiotics is as dramatic as the results of the human discovery. The rise of drug resistant bacteria is challenging the medical world as never before and threatening the advent of a post-antibiotic era that scientists are determined to forestall.
How To Overcome The Antibiotic Crisis
DOWNLOAD eBooks
Author : Marc Stadler
language : en
Publisher: Springer
Release Date : 2016-12-21
How To Overcome The Antibiotic Crisis written by Marc Stadler and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-21 with Medical categories.
This volume focuses on antibiotics research, a field of topical significance for human health due to the worrying increase of nosocomial infections caused by multi-resistant bacteria. It covers several basic aspects, such as the evolution of antibiotic resistance and the influence of antibiotics on the gut microbiota, and addresses the search for novel pathogenicity blockers as well as historical aspects of antibiotics. Further topics include applied aspects, such as drug discovery based on biodiversity and genome mining, optimization of lead structures by medicinal chemistry, total synthesis and drug delivery technologies. Moreover, the development of vaccines as a valid alternative therapeutic approach is outlined, while the importance of epidemiological studies on important bacterial pathogens, the problems arising from the excessive use of antibiotics in animal breeding, and the development of innovative technologies for diagnosing the “bad bugs” are discussed in detail. Accordingly, the book will appeal to researchers and clinicians alike.
Antimicrobial Resistance
DOWNLOAD eBooks
Author : Yashwant Kumar
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-05-02
Antimicrobial Resistance written by Yashwant Kumar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-02 with Medical categories.
The discovery of antibiotics was considered a milestone in health sciences and became the mainstay of antimicrobial therapy to treat and control bacterial infections. However, its utility has subsequently become limited, due to the emergence and spread of antimicrobial resistance among different bacterial species, which has emerged as a global threat. The development and spread of antimicrobial resistance have been attributed to many factors, including indiscriminate use of antibiotics in the healthcare and livestock industries. The present scenario of antibiotic resistance urgently requires interventions in terms of development of newer antimicrobials, evaluation of alternative therapies, and formulation of stringent policies to curb indiscriminate use of antimicrobials. This book highlights the importance and development of antimicrobial resistance in zoonotic, environmental and food bacteria, including the significance of candidate alternative therapies.
Drug Discovery Targeting Drug Resistant Bacteria
DOWNLOAD eBooks
Author : Prashant Kesharwani
language : en
Publisher: Academic Press
Release Date : 2020-05-15
Drug Discovery Targeting Drug Resistant Bacteria written by Prashant Kesharwani and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-15 with Medical categories.
Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war
Mechanisms Of Antibiotic Resistance
DOWNLOAD eBooks
Author : Jun Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-01
Mechanisms Of Antibiotic Resistance written by Jun Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Antibiotics categories.
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Silent Victories
DOWNLOAD eBooks
Author : John W. Ward
language : en
Publisher: Oxford University Press
Release Date : 2007
Silent Victories written by John W. Ward and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Medical categories.
Public health action often involved controversies and recriminations over past failures.
Technological Challenges In Antibiotic Discovery And Development
DOWNLOAD eBooks
Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2014-01-27
Technological Challenges In Antibiotic Discovery And Development written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-27 with Science categories.
Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.