The Autophagy Pathway Bacterial Pathogen Immunity And Evasion
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The Autophagy Pathway Bacterial Pathogen Immunity And Evasion
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Author : Chinnaswamy Jagannath
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-25
The Autophagy Pathway Bacterial Pathogen Immunity And Evasion written by Chinnaswamy Jagannath and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-25 with Science categories.
Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging
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Author : M. A. Hayat
language : en
Publisher: Elsevier
Release Date : 2013-09-03
Autophagy Cancer Other Pathologies Inflammation Immunity Infection And Aging written by M. A. Hayat and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-03 with Medical categories.
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers a valuable guide to cellular processes while encouraging researchers to explore their potentially important connections. Understanding the role of autophagy is critical, considering its association with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. This work will broaden the knowledge base of academic and clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process. Volumes in the Series
Wnt Signaling In Immune Cell Regulation During Microbial Infection And Cancer
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Author : Malini Sen
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-14
Wnt Signaling In Immune Cell Regulation During Microbial Infection And Cancer written by Malini Sen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-14 with categories.
Phagocytes In Immunity Linking Material Internalization To Immune Responses And Therapeutic Strategies
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Author : Johnathan Canton
language : en
Publisher: Frontiers Media SA
Release Date : 2021-11-12
Phagocytes In Immunity Linking Material Internalization To Immune Responses And Therapeutic Strategies written by Johnathan Canton and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-12 with Medical categories.
Autophagy
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Author : Daniel Klionsky
language : en
Publisher: CRC Press
Release Date : 2003-12-15
Autophagy written by Daniel Klionsky and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-15 with Science categories.
Starting in the early 1970s, a type of programmed cell death called apoptosis began to receive attention. Over the next three decades, research in this area continued at an accelerated rate. In the early 1990s, a second type of programmed cell death, autophagy, came into focus. Autophagy has been studied in mammalian cells for many years. The recen
Cell Signaling In Host Pathogen Interactions The Host Point Of View
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Author : Diana Bahia
language : en
Publisher: Frontiers Media SA
Release Date : 2018-03-23
Cell Signaling In Host Pathogen Interactions The Host Point Of View written by Diana Bahia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-23 with categories.
The ability of pathogens, such as parasites, bacteria, fungi and viruses to invade, persist and adapt in both invertebrate and vertebrate hosts is multifactorial and depends on both pathogen and host fitness. Communication between a pathogen and its host relies on a wide and dynamic array of molecular interactions. Through this constant communication most pathogens evolved to be relatively benign, whereas killing of its host by a pathogen represents a failure to adapt. Pathogens are lethal to their host when their interaction has not been long enough for adaptation. Evolution has selected conserved immune receptors that recognize signature patterns of pathogens as non-self elements and initiate host innate responses aimed at eradicating infection. Conversely, pathogens evolved mechanisms to evade immune recognition and subvert cytokine secretion in order to survive, replicate and cause disease. The cell signaling machinery is a critical component of the immune system that relays information from the receptors to the nucleus where transcription of key immune genes is activated. Host cells have developed signal transduction systems to maintain homeostasis with pathogens. Most cellular processes and cell signaling pathways are tightly regulated by protein phosphorylation in which protein kinases are key protagonists. Pathogens have developed multiple mechanisms to subvert important signal transduction pathways such as the mitogen activated protein kinase (MAPK) and the nuclear factor kB (NF-kB) pathways. Pathogens also secrete effectors that manipulate actin cytoskeleton and its regulators, hijack cell cycle machinery and alter vesicular trafficking. This research topic focuses on the cellular signaling mechanisms that are essential for host immunity and their subversion by pathogens.
The Role Of Autophagy In Infectious Diseases
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Author : Hua Niu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-08
The Role Of Autophagy In Infectious Diseases written by Hua Niu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-08 with Science categories.
The Inflammasome And Its Role In Infections
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Author : Amal O. Amer
language : en
Publisher: Frontiers E-books
Release Date :
The Inflammasome And Its Role In Infections written by Amal O. Amer and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Bacterial Effectors As Drivers Of Human Disease Models Methods Mechanisms
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Author : Teresa Thurston
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-13
Bacterial Effectors As Drivers Of Human Disease Models Methods Mechanisms written by Teresa Thurston and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-13 with Science categories.
Unifying Microbial Mechanisms
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Author : Michael F. Cole
language : en
Publisher: Garland Science
Release Date : 2019-09-09
Unifying Microbial Mechanisms written by Michael F. Cole and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-09 with Science categories.
Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject.