The Biochemistry Of Glycoproteins And Proteoglycans


The Biochemistry Of Glycoproteins And Proteoglycans
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The Biochemistry Of Glycoproteins And Proteoglycans


The Biochemistry Of Glycoproteins And Proteoglycans
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Author : William Lennarz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Biochemistry Of Glycoproteins And Proteoglycans written by William Lennarz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


Although glycoproteins and proteoglycans have been a subject of re search for many years, it is only during the last five or so years that they have aroused the interest of a very broad cross section of investigators in the biological sciences. The reason for this expanded interest in these molecules is simple: not only are glycoproteins and proteoglycans ubiq uitous, but many are molecules with well-defined and important biological functions. The list of molecules that fall into this category grows daily; interferon, immunoglobulins, certain hormones, many cell surface recep tors, and viral coat proteins are but a few examples. Thus, investigators with interests as diverse as viral replication. cell-cell interactions. poly isoprenoid synthesis, secretory processes, hormone responses, embryonic development, and immunology have become concerned with glycopro teins and proteoglycans. The objective of this book is to summarize the current state of knowledge on the biochemistry of these molecules. Coverage is by no means encyclopedic; rather the thrust is to emphasize the recent ad vances. The first chapter deals primarily with structural work on the oligosaccharide chains of glycoproteins, but it will be apparent in it and in the succeeding two chapters on biosynthesis that not only do structural studies aid biosynthetic investigations, but that studies on biosynthesis often playa major role in elucidation of structure.



Glycoprotein And Proteoglycan Techniques


Glycoprotein And Proteoglycan Techniques
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Author : J.G. Beeley
language : en
Publisher: Elsevier
Release Date : 2000-04-01

Glycoprotein And Proteoglycan Techniques written by J.G. Beeley and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-04-01 with Medical categories.


The past two decades have seen an expansion of interest in glycoproteins. From being a borderline area between carbohydrate and protein chemistry, it has become relevant to a wide range of biological phenomena. The aim of the book is to describe techniques which can be used to answer some of the basic questions about glycosylated proteins. Methods are discussed for isolation; compositional analysis; structure carbohydrate units; protein-carbohydrate linkages, keeping in mind the diverse nature of problems which readers may have to tackle.



The Glycoconjugates V2


The Glycoconjugates V2
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Author : Martin Horowitz
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Glycoconjugates V2 written by Martin Horowitz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.


The Glycoconjugates: Mammalian Glycoproteins, Glycolipids, and Proteoglycans Volume II is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The text of the second volume covers topics such as the structure and biosynthesis of connective tissue proteoglycans, glycoproteins, and glycolipids; and glycoprotein and glycolipid catabolism and degradation. It also discusses the structure, composition, and isolation of surface membranes; and lectins – its immunological aspects and its use in the study of mammalian glycoprotein. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.



The Glycoconjugates V3


The Glycoconjugates V3
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Author : Martin Horowitz
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Glycoconjugates V3 written by Martin Horowitz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


The Glycoconjugates: Mammalian Glycoproteins, Glycolipids, and Proteoglycans Volume III is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The third volume covers topics such as the glycosylation of proteins, inhibition of lipid-dependent glycosylation, and the relationship between translation and glycosylation. Also included are topics such as the intracellular transport of glycoproteins, the nonenzymatic glycosylation of proteins, and the glycosyltransferases and proteoglycans in the colon and B and T cells. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.



The Glycoconjugates V4


The Glycoconjugates V4
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Author : Martin Horowitz
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Glycoconjugates V4 written by Martin Horowitz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


The Glycoconjugates: Mammalian Glycoproteins, Glycolipids, and Proteoglycans Volume IV is a collaboration of different experts in the field of molecular biology on the subject of glycoconjugates. The fourth volume covers topics such as the uptake of glycoconjugates and transport of lysozomal enzymes, and the hepatic receptor for asialoglycoproteins. Also covered in this volume are topics such as the use of neoglycoproteins as probes for binding and cellular uptake of glycoconjugates; the transfer of glycoconjugates from living to fixed cells; and the biosynthesis, function, and host interaction of virus glycolipids and glycoproteins. The book is recommended for molecular biologists, organic chemists, and biochemists who would like to know more about glycolipids and glycoproteins and their applications.



Glycoprotein And Proteoglycan Techniques


Glycoprotein And Proteoglycan Techniques
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Author :
language : en
Publisher:
Release Date : 1989

Glycoprotein And Proteoglycan Techniques written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with categories.




Proteoglycans


Proteoglycans
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Author : John F. Kennedy
language : en
Publisher: Elsevier Science & Technology
Release Date : 1979

Proteoglycans written by John F. Kennedy and has been published by Elsevier Science & Technology this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Medical categories.




Glycoproteins


Glycoproteins
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Author : R. Colin Hughes
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Glycoproteins written by R. Colin Hughes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


The student of biological science in his final years as an undergraduate and his first years as a graduate is expected to gain some familiarity with current research at the frontiers of his discipline. New research work is published in a perplexing diversity of publications and is inevitably concerned with the minutiae of the subject. The sheer number of research journals and papers also causes confusion and difficulties of assimilation. Review articles usually presuppose a background know ledge of the field and are inevitably rather restricted in scope. There is thus a need for short but authoritative introductions to those areas of modern biological research which are either not dealt with in standard introductory textbooks or are not dealt with in sufficient detail to enable the student to go on from them to read scholarly reviews with profit. This series of books is designed to satisfy this need. The authors have been asked to produce a brief outline of their subject assuming that their readers will have read and remembered much of a standard introductory textbook of biology. This outline then sets out to provide by building on this basis, the conceptual framework within which modern research work is progressing and aims to give the reader an indication of the problems, both conceptual and practical, which must be overcome if progress is to be maintained.



Glycoconjugate Research


Glycoconjugate Research
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Author : John Gregory
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Glycoconjugate Research written by John Gregory and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Glycoconjugate Research, Volume I contains the proceedings of the Fourth International Symposium on Glycoconjugates, held in Woods Hole, Massachusetts, in September 1977. Contributors focus on the state of knowledge in the field of glycoconjugates ranging from polysaccharides and glycoproteins to glycolipids, proteoglycans, and all their varieties in plants, animals, and microorganisms. This text is organized into three sections and consists of 87 chapters. After an introductory chapter where the use of glycosidases for the structural analysis of complex carbohydrates is described, the discussion turns to other methods used for elucidating the structure of complex carbohydrates. The chapters that follow focus on the primary structure and conformation of glycans that are N-glycosically linked to peptide chains; isolation of monofuco-disialoganglioside from human and bovine brains; and partial chemical characterization of activated peptides isolated from a single cell suspension of rat colonic secretory cells. The last two sections explore cartilage proteoglycans and the structure-function relationships of glycoconjugates, touching on topics such as link proteins; the biochemical aspects of malignancy in human chondrosarcomas; defensive response of plants to a microbial oligosaccharide with a pheromone-like activity; and the interaction of saccharides with ricin. This book is intended for students and practitioners of chemistry and biochemistry; biology and microbiology; and physiology.



The Biology Of Glycoproteins


The Biology Of Glycoproteins
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Author : Raymond Ivatt
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

The Biology Of Glycoproteins written by Raymond Ivatt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


This book is in many ways a sequel to The Biochemistry ojGlycoproteins and Proteoglycans. The enormous recent progress in understanding the biological roles of glycoproteins has prompted the present volume. The reasons for studying glycoproteins have multiplied, and in the present volume the roles played by glycoproteins are explored in a variety of biological situations. The first two chapters describe molecules involved in cell-substratum and cell-cell interactions in a broad sense, and also focus on recent progress in identifying specific attachment molecules. Our understanding of how normal processes, such as cellular differentiation and tissue organization, are regulated is dependent on understanding how cells interact with the extracellular matrix. When these processes go awry the consequences can be tragic, for example, when manifest as birth de fects and cancer. Our ability to devise appropriate therapies is in many cases limited by our understanding of such cell-matrix interactions. The third chapter explores the roles by glycoproteins during early mammalian development. The carbohydrate portions c1early play very important roles in presenting information during early embryogenesis, and an unusual tumor stern cell, the embryonal carcinoma, looks very promising in pro viding an experimental system for understanding how the expression of these complex carbohydrate determinants is regulated. The next three chapters explore the biology of glycoproteins in distinct situations: in the immune system, in the nervous system, and during erythropoiesis.