The Biology Of Senescence
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The Biology Of Senescence
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Author : Alex Comfort
language : en
Publisher: Elsevier Publishing Company
Release Date : 1979
The Biology Of Senescence written by Alex Comfort and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Science categories.
The Biology Of Senescence
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Author : Bernard Swynghedauw
language : en
Publisher:
Release Date : 2019
The Biology Of Senescence written by Bernard Swynghedauw and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Family medicine categories.
This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for "treating" it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related "chronic non-transmissible diseases"), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to "treat" or "prevent" the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Ageing
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Author : Alex Comfort
language : en
Publisher:
Release Date : 1964
Ageing written by Alex Comfort and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1964 with Aging categories.
The Biology Of Aging
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Author : John A. Behnke
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Biology Of Aging written by John A. Behnke and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Egocentricity is characteristically human. It is natural for our prime in terest to be ourselves and for one of our major concerns to be what affects us personally. Aging and death - universal and inevitable have always been of compelling concern. Mystical explanations were invented when scientific answers were lacking. and gross physiologi As scientific knowledge developed, anatomy cal processes were explained, and the roles of the endocrine glands were revealed. Since the sex hormones obviously lose some of their potency with age, it was logical to assume that they played the major role in declining general well-being. The puzzle of aging would now be solved. The Ponce de Leon quest would soon be fulfilled. Pseudoscientists and quacks rushed in where most scientists feared to tread. By the time the glowing promises of perpetual youth through gland transplants and injections had proved illusory, serious study of the aging process had been set back for years. The field had lost "respect ability," and most capable scientists shunned it. Those who did con tinue to seek answers to its tough questions deserve special recognition.
Human Senescence
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Author : Douglas E. Crews
language : en
Publisher: Cambridge University Press
Release Date : 2003-12-11
Human Senescence written by Douglas E. Crews and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-11 with Science categories.
Much research on the biology of senescence is on cell-lines, nematodes or fruit flies, that are only of peripheral relevance to the problems encountered in humans. Human Senescence is a text which reviews the evolutionary biology of human senescence and life span, and the evolutionarily recent development of late-life survival. It examines how human patterns of and variability in growth and development have altered later life survival probabilities and competencies, and how survival during mid-life contributes to senescent dysfunction and alteration. Discussing possibilities of further extending human life span, it gives a better understanding of how humans came to senesce as slowly as we do over our lifespan. Bringing together gerontological, anthropological and biocultural research, it explores human variation in chronic disease, senescence and life span as outcomes of early life adaptation and the success of humankind's sociocultural evolution. It is a benchmark publication for all interested in how and why we age.
Times Cells And Aging
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Author : Bernard Strihler
language : en
Publisher: Academic Press
Release Date : 1977-01-28
Times Cells And Aging written by Bernard Strihler and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-01-28 with Science categories.
Time, Cells, and Aging, 2nd Edition presents the mechanics of cell function and the relevant implications of the molecular-genetic view to the aging phenomena. This book explores the biology of the aging process. Comprised of 11 chapters, this edition starts with an overview of the causes and mechanisms underlying the gradual deterioration of structure and function characteristics of aging. This text then examines the two aspects of the behavior of man, including the reasoned conscious behavior and the greater dependence on reaction patterns predicted on the successful responses of the past. Other chapters explore the relationship between aging and mortality rate in animals, which is a result of an organism's deceasing ability to function optimally in carrying out his vital functions. The final chapter deals with the implementation of a research plan relevant to understanding the primary mechanisms of the aging process. This book is a valuable resource for gerontologists, biologists, and molecular biologists.
Cellular Ageing And Replicative Senescence
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Author : Suresh I.S. Rattan
language : en
Publisher: Springer
Release Date : 2016-05-09
Cellular Ageing And Replicative Senescence written by Suresh I.S. Rattan and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-09 with Medical categories.
This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.
The Biology Of Senescence
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Author : Bernard Swynghedauw
language : en
Publisher: Springer
Release Date : 2020-08-15
The Biology Of Senescence written by Bernard Swynghedauw and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-15 with Medical categories.
This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for “treating” it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related “chronic non-transmissible diseases”), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to “treat” or “prevent” the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Longevity Senescence And The Genome
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Author : Caleb E. Finch
language : en
Publisher: University of Chicago Press
Release Date : 1994-05-16
Longevity Senescence And The Genome written by Caleb E. Finch and has been published by University of Chicago Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-05-16 with Health & Fitness categories.
Featuring extensive references, updated for this paperback edition, Longevity, Senescence, and the Genome constitutes a landmark contribution to biomedicine and the evolutionary biology of aging. To enhance gerontology's focus on human age-related dysfunctions, Caleb E. Finch provides a comparative review of all the phyla of organisms, broadening gerontology to intersect with behavioral, developmental, evolutionary, and molecular biology. By comparing species that have different developmental and life spans, Finch proposes an original typology of senescence from rapid to gradual to negligible, and he provides the first multiphyletic calculations of mortality rate constants.
Biochemistry And Cell Biology Of Ageing Part I Biomedical Science
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Author : J. Robin Harris
language : en
Publisher: Springer
Release Date : 2019-02-18
Biochemistry And Cell Biology Of Ageing Part I Biomedical Science written by J. Robin Harris and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-18 with Medical categories.
This new volume in the Subcellular Biochemistry series will focus on the biochemistry and cellular biology of aging processes in human cells. The chapters will be written by experts in their respective fields and will focus on a number of the current key areas of research in subcellular aging research. Main topics for discussion are mitochondrial aging, protein homeostasis and aging and the genetic processes that are involved in aging. There will also be chapters that are dedicated to the study of the roles of a variety of vitamins and minerals on aging and a number of other external factors (microbiological, ROS, inflammation, nutrition). This book will provide the reader with a state of the art overview of the subcellular aging field. This book will be published in cooperation with a second volume that will discuss the translation of the cell biology of aging to a more clinical setting and it is hoped that the combination of these two volumes will bring a deeper understanding of the links between the cell and the body during aging.