The Biosynthesis Of Secondary Metabolites
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The Biosynthesis Of Secondary Metabolites
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Author : R. B. Herbert
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Biosynthesis Of Secondary Metabolites written by R. B. Herbert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investiga tion of secondary metabolism began with curiosity about the struc tures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here. This account is primarily intended to be an introduction to the biosynthesis of secondary metabolites. I have also endeavoured, however, to make the book as comprehensive as possIble. This has meant that some of the material has had to be presented in abbrevi ated form. The abbreviated material is largely confined to particular sections of the book. The paragraphs marked with a dagger (t) can be omitted by the reader wishing to acquire a general introduction to the subject. A blend of the most significant and the most recent references is cited to provide the reader with ready access to the primary litera ture. This is clearly most necessary for the material presented in abbreviated form. Relevant reviews are also cited.
Secondary Metabolite Biosynthesis And Metabolism
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Author : Richard J. Petroski
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Secondary Metabolite Biosynthesis And Metabolism written by Richard J. Petroski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book was developed from the proceedings of the American Chemical Society, Division of Agricultural & Food Chemistry, subdivision of Natural Products Symposium "Biosynthesis and Metabolism of Secondary Natural Products" held in Atlanta, Georgia, April 1991. The objective of the conference was to bring together people from apparently diverse fields, ranging from biotechnology, metabolism, mechanistic organic chemistry, enzymology, fermentation, and biosynthesis, but who share a common interest in either the biosynthesis or the metabolism of natural products. It is our intention to help bridge the gap between the fields of mechanistic bio-organic chemistry and biotechnology. Our thanks go to Dr. Henry Yokoyama, co-organizer of the symposium, the authors who so kindly contributed chapters, the conference participants, and to those who assisted in the peer review process. We also thank the financial supporters of the symposium: ACS/AGFD, NIH General Medical Sciences, and the agricultural, pharmaceutical, biotechnology, and chromatography companies. A full list of the supporting corporations and institutions is given on the following page. Pharma-Tech and P.C., Inc. are manufacturers of instrumentation for high-speed countercurrent chromatography. We thank the Agricultural Research Service and the U. S. Department of Agriculture for granting me permission to co-organize the conference and for us to complete the book. Richard J. Petroski Susan P. McCormick USDA, ARS, National Center for Agricultural Utilization Research Peoria, IL 61604 June 10, 1992 vii CONTENTS ANTIBIOTICS Polyketide Synthetases: Enzyme Complexes and Multifunctional Proteins Directing the Biosynthesis of Bacterial Metabolites from Fatty Acids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 . . . . . . . . . . .
The Biosynthesis Of Secondary Metabolites
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Author : R.B. Herbert
language : en
Publisher: Springer Science & Business Media
Release Date : 1989-03-31
The Biosynthesis Of Secondary Metabolites written by R.B. Herbert and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-03-31 with Science categories.
The chief purpose of such new editions is to bring the text up to date. This I have tried to do. The danger with such endeavours is that the book becomes corpulent. This I have tried to avoid. In so doing I am evermore conscious of how much material has had to be omitted. As before the references (ca. 770 of them) which are cited are intended in part to provide the reader with access to material that has been omitted. I am deeply grateful to Mrs Marjorie Romanowicz for preparing the typed manuscript for this edition with customary accuracy and efficiency, to my wife Margaret for checking the references, and to research students Karl Cable, Lucy Hyatt, Mashupye Kgaphola and Andrew Knaggs for helping with the checking of the manuscript. Richard Herbert April 1988 Preface to the first edition This is a book about experiments and results of experiments. The results described are the fruit of thirty years' labour in the field of secondary metabolism. Secondary metabolism, more than any other part of the chemistry of life, has been the special preserve of organic chemists. Investigation of secondary metabolism began with curiosity about the structures of compounds isolated from natural sources, i.e. secondary metabolites. Coeval with structure determination there has been a curiosity about the origins and mechanism of formation of secondary metabolites (or natural products as they have been called). It is the experimental outcome of this curiosity that is described here.
The Biosynthesis Of Secondary Metabolites
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Author : Richard B. Herbert
language : en
Publisher: Chapman & Hall
Release Date : 1981
The Biosynthesis Of Secondary Metabolites written by Richard B. Herbert and has been published by Chapman & Hall this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Science categories.
An introduction to the subject for advanced undergraduate or beginning research workers. Updated in its content and reference. Covers the many new techniques developed since 1981 (1st ed.). Introductory chapters provide background information, while the rest of the book deals with individual groups of secondary metabolites. Paper edition, $29.50. Annotation copyrighted by Book News, Inc., Portland, OR
Plant Secondary Metabolism
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Author : David S. Seigler
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Plant Secondary Metabolism written by David S. Seigler and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Life has evolved as a unified system; no organism exists similar role also has been suggested for fatty acids from alone, but each is in intimate contact with other organisms cyanolipids. Nonprotein amino acids, cyanogenic glyco and its environment. Historically, it was easier for workers sides, and the non-fatty-acid portion of cyanolipids also are in various disciplines to delimit artificially their respective incorporated into primary metabolites during germination. areas of research, rather than attempt to understand the entire Secondary metabolites of these structural types are accumu system of living organisms. This was a pragmatic and neces lated in large quantities in the seeds of several plant groups sary way to develop an understanding for the various parts. where they probably fulfill an additional function as deter We are now at a point, however, where we need to investi rents to general predation. gate those things common to the parts and, specifically, those The second type of relationship involves interaction of things that unify the parts. The fundamental aspects of many plants with other organisms and with their environment. Bio of these interactions are chemical in nature. Plants constitute logical interactions must be viewed in the light of evolution an essential part of all life systems; phytochemistry provides ary change and the coadaptation, or perhaps coevolution, of a medium for linking several fields of study.
Biotechnology
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Author : K.G. Ramawat
language : en
Publisher: CRC Press
Release Date : 2007-01-01
Biotechnology written by K.G. Ramawat and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-01 with Nature categories.
This book provides new information relating recent advances made in the field of plant secondary products. Besides the updation of chapters this edition also includes chapters on secondary metabolites of microorganisms (fungi and lichen).
Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites
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Author : Juan-Francisco Martín
language : en
Publisher: Springer
Release Date : 2014-09-09
Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites written by Juan-Francisco Martín and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-09 with Science categories.
This volume describes the more relevant secondary metabolites of different fungi with current information on their biosynthesis and molecular genetics. Bolstered with color illustrations and photographs, the book describes the possible application of molecular genetics to directed strain improvement in great detail. The needs for future developments in this field are also discussed at length Written by authorities in the field, Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites provides a cutting-edge perspective on fungal secondary metabolism and underlying genetics and is a valuable resource for scientists, researchers, and educators in the field of fungal biology.
The Biosynthesis Of Mycotoxins
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Author : Pieter Steyn
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Biosynthesis Of Mycotoxins written by Pieter Steyn and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.
The Biosynthesis of Mycotoxins: A Study in Secondary Metabolism focuses on the biosynthetic analysis of mycotoxins, which are inherently a heterogeneous group of metabolites that are formed along the terpene route and the route polyketide, as well as from amino acids. This book discusses the unique biological properties and structural complexity of the highly specialized secondary microbial metabolites. Organized into 12 chapters, this book starts with an overview of the characteristics of secondary metabolites, including their problematic function and the combination of their structural diversity with their restricted biological occurrence. This text then explains the sporadic occurrence of the mycotoxins as fungal metabolites. Other chapters explore ergochromes, which are a group of light yellow mycotoxins that are isolated from ergot, mold fungi, and lichens. The final chapter discusses the biosynthesis of several unrelated fungal metabolites for which toxicological data are reported. Biochemists, organic chemists, mycologists, enzymologists, plant pathologists, toxicologists, and graduate students will find this book useful.
Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites Volume 2
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Author : Susanne Zeilinger
language : en
Publisher: Springer
Release Date : 2015-06-15
Biosynthesis And Molecular Genetics Of Fungal Secondary Metabolites Volume 2 written by Susanne Zeilinger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-15 with Science categories.
Fungi produce many chemically diverse secondary metabolites whose biological roles largely remain elusive. Within the increasing number of sequenced fungal genomes several important genes involved in secondary metabolite formation have been identified. Most of these genes are clustered and their coordinated transcription is controlled in a complex way by both narrow pathway-specific regulators as well as broad global transcription factors responsive to environmental cues. In recent years it was discovered many of the newly identified gene clusters are silent under laboratory conditions suggesting that the biosynthetic potential of fungi is far from being exploited. Besides identifying novel bioactive metabolites from still unexplored sources, the activation of these gene clusters by several approaches may result in the discovery of new substances with antibiotic and pharmaceutical benefits. This book covers recent advances in the field of fungal secondary metabolisms ranging from methodologies to biological aspects and will include the latest knowledge on fungal molecular biology, genomics, and metabolomics. With the related volume by Professor Juan-Francisco Martin, where the most relevant and well-studied fungal secondary metabolites are compiled, this book provides a comprehensive overview of the state-of-the-art of research on fungal secondary metabolites.
Metabolic Engineering Of Plant Secondary Metabolism
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Author : R. Verpoorte
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Metabolic Engineering Of Plant Secondary Metabolism written by R. Verpoorte and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Science categories.
Plant secondary metabolism is an economically important source of fine chemicals, such as drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such as taste, flavour, smell, colour, or resistance against pests and diseases are also related to secondary metabolites. The genetic modification of plants is feasible nowadays. What does the possibility of engineering plant secondary metabolite pathways mean? In this book, firstly a general introduction is given on plant secondary metabolism, followed by an overview of the possible approaches that could be used to alter secondary metabolite pathways. In a series of chapters from various authorities in the field, an overview is given of the state of the art for important groups of secondary metabolites. No books have been published on this topic so far. This book will thus be a unique source of information for all those involved with plants as chemical factories of fine chemicals and those involved with the quality of food and ornamental plants. It will be useful in teaching graduate courses in the field of metabolic engineering in plants.