The Case Against The Drugged Mind
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The Case Against The Drugged Mind
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Author : Andrew I. Malcolm
language : en
Publisher: Toronto: Clarke, Irwin
Release Date : 1973
The Case Against The Drugged Mind written by Andrew I. Malcolm and has been published by Toronto: Clarke, Irwin this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Medical categories.
This Is Your Mind On Plants
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Author : Michael Pollan
language : en
Publisher: Penguin UK
Release Date : 2021-07-08
This Is Your Mind On Plants written by Michael Pollan and has been published by Penguin UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-08 with Science categories.
THE INSPIRATION FOR THE MAJOR NEW NETFLIX SERIES, HOW TO CHANGE YOUR MIND 'It's a trip - engrossing, eye-opening, mind altering' New Statesman 'Fascinating. Pollan is the perfect guide ... curious, careful, open minded' The Guardian Of all the many things humans rely on plants for, surely the most curious is our use of them to change consciousness: to stimulate, calm, or completely alter the qualities of our mental experience. In This Is Your Mind On Plants, Michael Pollan explores three very different drugs - opium, caffeine and mescaline - and throws the fundamental strangeness of our thinking about them into sharp relief. Exploring and participating in the cultures that have grown up around these drugs, while consuming (or in the case of caffeine, trying not to consume) them, Pollan reckons with the powerful human attraction to psychoactive plants, and the equally powerful taboos. In a unique blend of history, science, memoir and reportage, Pollan shines a fresh light on a subject that is all too often treated reductively. In doing so, he proves that there is much more to say about these plants than simply debating their regulation, for when we take them into our bodies and let them change our minds, we are engaging with nature in one of the most profound ways we can. This ground-breaking and singular book holds up a mirror to our fundamental human needs and aspirations, the operations of our minds and our entanglement with the natural world.
Drugged
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Author : Richard J. Miller
language : en
Publisher: Oxford University Press, USA
Release Date : 2014
Drugged written by Richard J. Miller and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with History categories.
Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.
Blood Brain Barrier In Drug Discovery
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Author : Li Di
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-02
Blood Brain Barrier In Drug Discovery written by Li Di and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-02 with Medical categories.
Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration or minimize CNS side-effects • Reviews state-of-the-art in silico, in vitro, and in vivo tools to assess brain penetration and advanced CNS drug delivery strategies • Covers BBB physiology, medicinal chemistry design principles, free drug hypothesis for the BBB, and transport mechanisms including passive diffusion, uptake/efflux transporters, and receptor-mediated processes • Highlights the advances in modelling BBB pharmacokinetics and dynamics relationships (PK/PD) and physiologically-based pharmacokinetics (PBPK) • Discusses case studies of successful CNS and non-CNS drugs, lessons learned and paths to the market
Direct Nose To Brain Drug Delivery
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Author : Chandrakantsing Pardeshi
language : en
Publisher: Academic Press
Release Date : 2021-06-16
Direct Nose To Brain Drug Delivery written by Chandrakantsing Pardeshi and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-16 with Business & Economics categories.
Direct Nose-to-Brain Drug Delivery provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration and includes an overview on the toxicity aspects of the various materials used to develop the direct nose-to-brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. This book is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose-to-brain Discusses pharmaceutical and biomedical applications after nose-to-brain delivery of therapeutic pharmaceuticals and biologicals
Brain Drug Targeting
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Author : William M. Pardridge
language : en
Publisher: Cambridge University Press
Release Date : 2001-05-31
Brain Drug Targeting written by William M. Pardridge and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-31 with Medical categories.
This challenging 2001 book reviews modern neurotherapeutics from the point of view of drug targeting.
Drug Delivery To The Brain
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Author : Margareta Hammarlund-Udenaes
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-03
Drug Delivery To The Brain written by Margareta Hammarlund-Udenaes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-03 with Medical categories.
The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications.
Nanocarriers For Drug Targeting Brain Tumors
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Author : Lalit Kumar
language : en
Publisher: Elsevier
Release Date : 2022-06-21
Nanocarriers For Drug Targeting Brain Tumors written by Lalit Kumar and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-21 with Technology & Engineering categories.
Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. Provides information on the design and development of nanocarriers for targeting brain tumors Outlines the working principles of different nanocarriers for targeting brain tumors Includes case studies of different nanocarriers for targeting brain tumors
Nanoarchitectonics For Brain Drug Delivery
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Author : Anurag Kumar Singh
language : en
Publisher: CRC Press
Release Date : 2024-02-22
Nanoarchitectonics For Brain Drug Delivery written by Anurag Kumar Singh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-22 with Technology & Engineering categories.
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain delivery Provides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancer Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS Reviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.
Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience For Theranostics Applications
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Author : Ram Kumar Sahu
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-09-02
Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience For Theranostics Applications written by Ram Kumar Sahu and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-02 with Medical categories.
Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment. Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment. This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy. Key Features: Structured chapters for easy understanding of nanotechnology concepts In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment References for further reading and exploring new advances in drug delivery systems