The Cell Cycle In The Central Nervous System
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The Cell Cycle In The Central Nervous System
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Author : Damir Janigro
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-01-23
The Cell Cycle In The Central Nervous System written by Damir Janigro and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-23 with Science categories.
Cell Cycle in the Central Nervous System overviews the changes in cell cycle as they relate to prenatal and post natal brain development, progression to neurological disease or tumor formation.Topics covered range from the cell cycle during the prenatal development of the mammalian central nervous system to future directions in postnatal neurogenesis through gene transfer, electrical stimulation, and stem cell introduction. Additional chapters examine the postnatal development of neurons and glia, the regulation of cell cycle in glia, and how that regulation may fail in pretumor conditions or following a nonneoplastic CNS response to injury. Highlights include treatments of the effects of deep brain stimulation on brain development and repair; the connection between the electrophysiological properties of neuroglia, cell cycle, and tumor progression; and the varied immunological responses and their regulation by cell cycle.
Combined Modality Therapy Of Central Nervous System Tumors
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Author : Zbigniew Petrovich
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Combined Modality Therapy Of Central Nervous System Tumors written by Zbigniew Petrovich and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50% are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well as metastatic disease are covered in depth. Even though management is difficult, advances are being made. This book is a concerted effort to present data regarding basic science research efforts alongside their translation into clinical practice using combined, integrated multimodal programs of treatment. Progress has been made, but innovatice approaches need to be pursued.
Cell Cycle Mechanisms And Neuronal Cell Death
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Author : Agata Copani
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06
Cell Cycle Mechanisms And Neuronal Cell Death written by Agata Copani and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Science categories.
Cell-Cycle Mechanisms and Neuronal Cell Death examines the role of cell cycle activation in the molecular mechanisms leading to neuronal degeneration. Leading Authors discuss this topic in relation to the major neurological disorders, including Alzheimer’s disease, stroke and epilepsy. This book serves to gain new insights into the molecular determinants of neuronal death and to establish new targets for therapeutic intervention.
Stem And Progenitor Cells In The Central Nervous System
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Author : R.S. Nowakowski
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2004
Stem And Progenitor Cells In The Central Nervous System written by R.S. Nowakowski and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
This publication focuses on the biology of stem and progenitor cells in the developing and mature central nervous system, their response to trauma and potential uses in therapy. The authors, who are leading experts in the field, address topical questions from both basic and clinical neuroscience perspectives such as: non-invasive imaging of stem cell division; the origins of regional diversity in cell types and cell numbers in the stem cell progeny; factors that regulate generation of neurons and glial cells from stem cells during normal development; the role of genetic and environmental factors in the regulation of stem cell function; the role of stem cells in mediating the effects of brain trauma and its recovery, and the therapeutic uses of stem cells. Offering a unique compilation of articles on the biology and the therapeutic applications of stem cells in the embryonic and mature nervous systems, this volume will be of great value to neuroscientists, developmental biologists, cancer biologists and clinical neurologists.
Development Of The Nervous System
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Author : Dan H. Sanes
language : en
Publisher: Elsevier
Release Date : 2005-11-02
Development Of The Nervous System written by Dan H. Sanes and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-02 with Science categories.
Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. - Updates information including all the new developments made in the field since the first edition - Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated
Immediate Early Genes In The Central Nervous System
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Author : T.R. Tölle
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Immediate Early Genes In The Central Nervous System written by T.R. Tölle and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Immediate-early genes are believed to be involved in the neuron's ability to con vert short-term synaptic stimulation into long-lasting responses and thus contribute to the adaptive alterations involved in neuronal plasticity. Cellular immediate-early genes share a close structural homology with some viral oncogenes. Recent advances in cellular biology have identified the activation and deactivation of immediate-early genes as molecular mechanisms to control regulated and deregulated growth, cellular differentiation and development. In this view immediate-early genes may function as third messengers in a stimulus transcription cascade transferring extracellular information into changes in target gene transcription, thereby changing the phenotype of neurons. Immediate-Early Genes in the Central Nervous System provides a comprehensive up-to-date overview of current methodology in the research of immediate-early genes and includes a wide range of neurobiological topics, such as regeneration, memory formation, epilepsia and nociception. The contributors to this book have been selected from among the leading experts in their field of research. T.R. TOLLE J. SCHADRACK W. ZIEGLGANSBERGER Contents Immediate-early genes -how immmediate and why early? G./. Evan .............................................. . Immediate-early gene activation as a window on mechanism in the nervous system S.P. Hunt, L.A. McNaughton, R. Jenkins, and W. Wisden. . . . . . . . . .. . . . 18 of immediate-early genes during Differential expression synaptic plasticity, seizures and brain injury suggests specific functions for these molecules in brain neurons M. Dragunow . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . 35 . . . . . . . . . .
Cell Cycle Control
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Author : Anna Castro
language : en
Publisher: Springer Nature
Release Date : 2024-02-23
Cell Cycle Control written by Anna Castro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-23 with Science categories.
This detailed volume collects techniques to study the highly regulated cell cycle process. Beginning with chapters investigating these processes and assessing how cells respond when these complicated pathways are simplified by using synthetic biology and in vitro reconstitutions, the book continues by exploring how cells sense and respond to environmental conditions, different model systems and cellular types used to visualize cellular architecture during cell division, as well as innovative single cell microscopy techniques to highlight the heterogeneity of the cell population with respect to cell cycle progression. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cell Cycle Control: Methods and Protocols serves as an ideal guide for researchers attempting to elucidate this vital area of cell biology.
Cell Cycle Regulation And Differentiation In Cardiovascular And Neural Systems
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Author : Antonio Giordano
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-17
Cell Cycle Regulation And Differentiation In Cardiovascular And Neural Systems written by Antonio Giordano and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-17 with Medical categories.
Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.
The Cell Cycle And Development
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Author : Gregory R. Bock
language : en
Publisher: John Wiley and Sons
Release Date : 2001-06-29
The Cell Cycle And Development written by Gregory R. Bock and has been published by John Wiley and Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-29 with Science categories.
This book brings together scientists working at the interface between the cell cycle, cell growth and development in a variety of model systems and research paradigms. The focus is on understanding how such diverse developmental inputs can modulate cell cycle regulation and, reciprocally, how a common way of regulating cell cycle progression can participate in different developmental strategies.
Tumors Of The Central Nervous System Volume 3
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Author : M.A. Hayat
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-27
Tumors Of The Central Nervous System Volume 3 written by M.A. Hayat and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-27 with Medical categories.
The classification of brain tumors is up-dated using magnetic resonance spectroscopy technology. The role of cellular immortality in brain tumors is reviewed. Tumor to tumor metastases are a common occurrence; for example, , brain metastasis from breast cancer, lung cancer, and renal cancer is discussed. Genetic profiling and treatment (including neurosurgery) of such brain cancers are explained. Breast cancer patients treated with certain drugs (e.g., capecitabine and lapatinib can develop CNS tumors. Role of brain tumor suppressor genes (e.g., NRP/B gene) is pointed out. Biomarkers used to diagnose brain malignancies are explained in detail. A number of imaging modalities used for diagnosing and assessing the effectiveness of treatments of brain tumors are presented. The imaging methods discussed include MRI, PET, CT, MRSi, and SPECT. Also, is discussed the impact of PET using radiolabeled amino acids on brain tumors.