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The Centrosome And Its Functions And Dysfunctions


The Centrosome And Its Functions And Dysfunctions
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The Centrosome And Its Functions And Dysfunctions


The Centrosome And Its Functions And Dysfunctions
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Author : Heide Schatten
language : en
Publisher: Springer Nature
Release Date : 2022-12-16

The Centrosome And Its Functions And Dysfunctions written by Heide Schatten and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-16 with Science categories.


The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders. This new volume reviews the latest advances in the field and provides valuable background information that is readily understandable for the newcomer and the experienced centrosome researcher alike. Due to the interdisciplinary of the subject, it is a valuable resource for researchers and clinicians working in biomedical research, cell biology, cancer biology, reproduction and developmental biology, neuroscience and stem cell research.



The Centrosome


The Centrosome
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Author : Heide Schatten
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-13

The Centrosome written by Heide Schatten and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-13 with Science categories.


The Centrosome: Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease includes chapters on classic and modern aspects of centrosome research to cover topics of current interest that have not been covered in depth in most books on the market so far. It extends on previous topics and includes new exciting aspects of centrosome research focused on primary cilia and their dysfunctions that are implicated in numerous diseases. Each chapter will be written by experts in their fields who will contribute their unique expertise in specific research fields and include cell and molecular details that are important for the specific subtopics. The book will be comprehensive, concise and will include reviews of key topics in the field. Cutting edge new information will be balanced with background information that will be readily understandable for the newcomer and the experienced centrosome researcher alike.



Molecular Mechanisms Of Glutamatergic Synapse Function And Dysfunction


Molecular Mechanisms Of Glutamatergic Synapse Function And Dysfunction
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Author : Dhrubajyoti Chowdhury
language : en
Publisher: Frontiers Media SA
Release Date : 2022-12-22

Molecular Mechanisms Of Glutamatergic Synapse Function And Dysfunction written by Dhrubajyoti Chowdhury and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-22 with Science categories.




Psychiatric Disorders


Psychiatric Disorders
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Author : Toru Uehara
language : en
Publisher: BoD – Books on Demand
Release Date : 2011-10-26

Psychiatric Disorders written by Toru Uehara and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-26 with Medical categories.


Due to their prevalence, pervasiveness and burden inflicted on men and women of today, psychiatric disorders are considered as one of the most important, sever and painful illnesses. This impairment of cognitive, emotional, or behavioural functioning is in some cases tragic. Aside from knowing the physical organic factors, such as infections, endocrinal illnesses or head injuries, the aetiology of psychiatric disorders has remained a mystery. However, recent advances in psychiatry and neuroscience have been successful in discovering subsequent pathophysiology and reaching associated bio-psycho-social factors. This book consists of recent trends and developments in psychiatry from all over the world, presented in the form of multifarious and comprehensive articles. The first two sections of the book are reserved for articles on schizophrenia and depression, two major illnesses present in this field. The third section of the book is reserved for addiction psychiatry, related not only to socio-cultural but also biological alterations. The last section of the book, titled Biological Neuropsychiatry, consists of three topics - updated molecular biology, fundamental neuroscience and clinical neuropsychiatric conditions. Doubtlessly, this book will be fruitful for future developments and collaboration in world psychiatry.



Male Reproductive Dysfunction


Male Reproductive Dysfunction
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Author : Basu SC
language : en
Publisher: JP Medical Ltd
Release Date : 2011-05-30

Male Reproductive Dysfunction written by Basu SC and has been published by JP Medical Ltd this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-30 with Medical categories.


The second edition of Male Reproductive Dysfunction has been completely updated to present the most recent information on the subject. The book begins with a brief historical review of reproductive science, and then examines make reproductive anatomy and physiology, and the various causes of infertility. An updated chapter on the role of Assisted Reproductive Technology (ART) is included, as well as discussion on the psychological impact of infertility. Well-illustrated diagrams and tables help explain the different causes and their treatment.



Factors Affecting Neurological Aging


Factors Affecting Neurological Aging
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Author : Colin R. Martin
language : en
Publisher: Academic Press
Release Date : 2021-06-01

Factors Affecting Neurological Aging written by Colin R. Martin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-01 with Psychology categories.


Factors Affecting Neurological Aging: Genetics, Neurology, Behavior, and Diet is a comprehensive reference on the genetic and behavioral features associated with neurological aging and associated disorders. This book discusses the mechanisms underlying neurological aging and provides readers with a detailed introduction to the aging of neural connections and complexities in biological circuitries, as well as the physiological, behavioral, molecular, and cellular features of neurological aging. Finally, this comprehensive resource examines the use of animal modeling of aging and neurological disease. - Provides the most comprehensive coverage on a broad range of topics related to the neuroscience of aging - Features sections on the genetic components that influence aging and diseases of aging - Focuses on neurological diseases and conditions linked to aging, environmental factors and clinical recommendations - Includes more than 500 illustrations and tables



Principles Of Cloning


Principles Of Cloning
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Author : Jose Cibelli
language : en
Publisher: Academic Press
Release Date : 2013-09-24

Principles Of Cloning written by Jose Cibelli and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-24 with Science categories.


Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. - First and most comprehensive book on animal cloning, 100% revised - Describes an in-depth analysis of current limitations of the technology and research areas to explore - Offers cloning applications on basic biology, agriculture, biotechnology, and medicine



The Cytoskeleton In Health And Disease


The Cytoskeleton In Health And Disease
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Author : Heide Schatten
language : en
Publisher: Springer
Release Date : 2015-08-21

The Cytoskeleton In Health And Disease written by Heide Schatten and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-21 with Science categories.


This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion of microtubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems. Comprehensive yet concise. The Cytoskeleton In Health And Disease presents cutting-edge discoveries balanced with background information and highlights the new aspects of the research and its impact on the design of new strategies or the identification of new targets for therapeutic intervention. There is a significant need for a book on this topic, as interest in the cytoskeleton continues to grow as causes and cures for cytoskeletal diseases are further explored in biomedical research. This book is essential reading for scientists, students, and teachers interested in expanding their knowledge related to the cytoskeleton. New researchers entering the field will find classic and well as contemporary information not easily found in the current literature or internet resources.



Molecular Biology Of The Cell


Molecular Biology Of The Cell
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Author :
language : en
Publisher:
Release Date : 2004

Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.




Mechanisms And Genetics Of Neurodevelopmental Cognitive Disorders


Mechanisms And Genetics Of Neurodevelopmental Cognitive Disorders
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Author : Moyra Smith
language : en
Publisher: Academic Press
Release Date : 2021-04-25

Mechanisms And Genetics Of Neurodevelopmental Cognitive Disorders written by Moyra Smith and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-25 with Medical categories.


Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders connects neurodevelopment with genetics and behavior to better understand the underlying factors leading to cognitive neurodevelopmental disorders. This book focuses on mechanisms of disease and follows the development of specific brain regions, functions, and gene expression to causes and processes in autism, attention deficit disorder, and learning disabilities. Topics include brain mapping, brain plasticity, epigenetics, neuroimmunology, and many other factors that influence the development of these diseases. This book will promote understanding of recent investigations and developments related to brain development from fetal life onward with specific relevance to neurodevelopmental cognitive disorders and conditions. This is an essential reference for anyone who is looking to learn more about different aspects of neurodevelopment and emerging concepts in psychiatric disorders. - Discusses links between brain development, gene expression, and brain function - Covers neural stem cells, proliferation, migration, differentiation, and neurogenesis - Includes brain mapping, brain plasticity, epigenetics, neuroimmunology, and more - Provides insight into causation and brain function in autism, attention deficit disorder, and learning disabilities - Examines impact of society and environmental factors on mental health