The Centrosome In Cell Replication And Early Development
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The Centrosome In Cell Replication And Early Development
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Author :
language : en
Publisher: Elsevier
Release Date : 2000-09-26
The Centrosome In Cell Replication And Early Development written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-26 with Science categories.
Centrosomes play an integral role in the growth of cells and the ultimate development of many animals, and sometimes plants. In addition to the normal growth of cells, centrosomes can also play a key role in the spread of cancer and are of increased interest to both the genetics and oncology communities. Volume 49 of Current Topics in Developmental Biology will present all known research surrounding the centrosome, across a variety of systems, will be well referenced, and speculate where the research is headed. Discusses centrosomes and cancer, centrosomes and early development, and molecular biology of the centrosome Heavily illustrated, with many color figures Chapters written by international leaders in the field
Maternal Control Of Development In Vertebrates
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Author : Florence Louise Marlow
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010
Maternal Control Of Development In Vertebrates written by Florence Louise Marlow and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Family & Relationships categories.
Eggs of all animals contain mRNAs and proteins that are supplied to or deposited in the egg as it develops during oogenesis. These maternal gene products regulate all aspects of oocyte development, and an embryo fully relies on these maternal gene products for all aspects of its early development, including fertilization, transitions between meiotic and mitotic cell cycles, and activation of its own genome. Given the diverse processes required to produce a developmentally competent egg and embryo, it is not surprising that maternal gene products are not only essential for normal embryonic development but also for fertility. This review provides an overview of fundamental aspects of oocyte and early embryonic development and the interference and genetic approaches that have provided access to maternally regulated aspects of vertebrate development. Some of the pathways and molecules highlighted in this review, in particular, Bmps, Wnts, small GTPases, cytoskeletal components, and cell cycle regulators, are well known and are essential regulators of multiple aspects of animal development, including oogenesis, early embryogenesis, organogenesis, and reproductive fitness of the adult animal. Specific examples of developmental processes under maternal control and the essential proteins will be explored in each chapter, and where known conserved aspects or divergent roles for these maternal regulators of early vertebrate development will be discussed throughout this review. Table of Contents: Introduction / Oogenesis: From Germline Stem Cells to Germline Cysts / Oocyte Polarity and the Embryonic Axes: The Balbiani Body, an Ancient Oocyte Asymmetry / Preparing Developmentally Competent Eggs / Egg Activation / Blocking Polyspermy / Cleavage/ Mitosis: Going Multicellular / Maternal-Zygotic Transition / Reprogramming: Epigenetic Modifications and Zygotic Genome Activation / Dorsal-Ventral Axis Formation before Zygotic Genome Activation in Zebrafish and Frogs / Maternal TGF-β and the Dorsal-Ventral Embryonic Axis / Maternal Control After Zygotic Genome Activation / Compensation by Stable Maternal Proteins / Maternal Contributions to Germline Establishment or Maintenance / Perspective / Acknowledgments / References
Molecular Biology Of The Cell
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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002
Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.
Landmark Papers In Cell Biology
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Author : Joseph G. Gall
language : en
Publisher: CSHL Press
Release Date : 2001
Landmark Papers In Cell Biology written by Joseph G. Gall and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Cells categories.
Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).
Eukaryotic Membranes And Cytoskeleton
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Author : Gáspár Jékely
language : en
Publisher: Springer
Release Date : 2010-10-27
Eukaryotic Membranes And Cytoskeleton written by Gáspár Jékely and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-27 with Science categories.
The presence/absence of gene families with central roles in endomembrane and cytoskeleton dynamics in a variety of eukaryotic taxa and an understanding of eukaryote phylogeny allow the cellular machineries present in the last common ancestor of eukaryotes to be accurately reconstructed. Such a reconstruction is fundamental in order to understand eukaryotic diversification, since this is the ancestral cell from which all diversity arose. This book discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective.
Principles Of Cloning
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Author : Jose Cibelli
language : en
Publisher: Academic Press
Release Date : 2013-09-24
Principles Of Cloning written by Jose Cibelli and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-09-24 with Science categories.
Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. First and most comprehensive book on animal cloning, 100% revised Describes an in-depth analysis of current limitations of the technology and research areas to explore Offers cloning applications on basic biology, agriculture, biotechnology, and medicine
Centrosome And Centriole
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Author :
language : en
Publisher: Academic Press
Release Date : 2015-09-10
Centrosome And Centriole written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-10 with Science categories.
This new volume of Methods in Cell Biology looks at methods for analyzing centrosomes and centrioles. Chapters cover such topics as methods to analyze centrosomes, centriole biogenesis and function in multi-ciliated cells, laser manipulation of centrosomes or CLEM, analysis of centrosomes in human cancers and tissues, proximity interaction techniques to study centrosomes, and genome engineering for creating conditional alleles in human cells. Covers sections on model systems and functional studies, imaging-based approaches and emerging studies Chapters are written by experts in the field Cutting-edge material
Cytokinesis In Animal Cells
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Author : R. Rappaport
language : en
Publisher: Cambridge University Press
Release Date : 1996-10-28
Cytokinesis In Animal Cells written by R. Rappaport and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-10-28 with Medical categories.
This book traces the history of the major ideas and gives an account of our current knowledge of cytokinesis.
Genome Instability In Cancer Development
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Author : Erich A. Nigg
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-01-14
Genome Instability In Cancer Development written by Erich A. Nigg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-14 with Medical categories.
Research over the past decades has firmly established the genetic basis of cancer. In particular, studies on animal tumour viruses and chromosome rearrangements in human tumours have concurred to identify so-called ‘proto-oncogenes’ and ‘tumour suppressor genes’, whose deregulation promotes carcinogenesis. These important findings not only explain the occurrence of certain hereditary tumours, but they also set the stage for the development of anti-cancer drugs that specifically target activated oncogenes. However, in spite of tremendous progress towards the elucidation of key signalling pathways involved in carcinogenesis, most cancers continue to elude currently available therapies. This stands as a reminder that “cancer” is an extraordinarily complex disease: although some cancers of the haematopoietic system show only a limited number of characteristic chromosomal aberrations, most solid tumours display a myriad of genetic changes and considerable genetic heterogeneity. This is thought to reflect a trait commonly referred to as ‘genome instability’, so that no two cancers are ever likely to display the exact same genetic alterations. Numerical and structural chromosome aberrations were recognised as a hallmark of human tumours for more than a century. Yet, the causes and consequences of these aberrations still remain to be fully understood. In particular, the question of how genome instability impacts on the development of human cancers continues to evoke intense debate.
Centrosomes In Development And Disease
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Author : Erich A. Nigg
language : en
Publisher: John Wiley & Sons
Release Date : 2006-01-24
Centrosomes In Development And Disease written by Erich A. Nigg and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-24 with Science categories.
Discovered over a century ago, the centrosome is the major microtubule organizing center of the animal cell. It is a tiny organelle of surprising structural complexity. Over the last few years our understanding of the structure and composition of centrosomes has greatly advanced, and the demonstration of frequent centrosome anomalies in most common human tumors has sparked additional interest in the role of this organelle in a broader scientific community. The centrosome controls the number and distribution of microtubules - a major element of the cell cytoskeleton - and hence influences many important cellular functions and properties. These include cell shape, polarity, and motility, as well as the intracellular transport and positioning of various organelles. Of particular interest, centrosome function is critical for chromosome segregation and cell division. This book is meant to summarize our current knowledge of the structure, function and evolution of microtubule organizing centers, primarily centrosomes. Emphasis is on the role of these organelles in development and disease (particularly cancer).