The Comparative Molecular Biology Of Extracellular Matrices


The Comparative Molecular Biology Of Extracellular Matrices
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The Comparative Molecular Biology Of Extracellular Matrices


The Comparative Molecular Biology Of Extracellular Matrices
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Author : Harold Slavkin
language : en
Publisher: Academic Press
Release Date : 2012-12-02

The Comparative Molecular Biology Of Extracellular Matrices written by Harold Slavkin and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


The Comparative Molecular Biology of Extracellular Matrices reviews and assesses the comparative molecular biology of extracellular matrices. It covers six areas that are advanced to supplement this study. These include the molecular biology of collagen, monopolysaccharides, proteoglycans, and structural glycoproteins; development process of extracellular matrices; cell surfaces and interactions; evolution of bone and some tissues; and biophysical properties of connective tissues.



Cell Biology Of Extracellular Matrix


Cell Biology Of Extracellular Matrix
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Author : E.D. Hay
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Cell Biology Of Extracellular Matrix written by E.D. Hay and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.


In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .



Extracellular Matrix Genes


Extracellular Matrix Genes
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Author : Charles Boyd
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Extracellular Matrix Genes written by Charles Boyd and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Medical categories.


Extracellular Matrix Genes provides some of the interesting complexities of the structure of the entire family of extracellular matrix genes. This book illustrates the permanent role that molecular biology and molecular genetics play in the detailed understanding of the normal biology of extracellular matrix. Organized into 10 chapters, this book begins with an overview of the structural and sequence aspects of the entire family of genomic sequences with a view to establishing common functional domains among collagens and their genes. This text then examines the status of the literature concerning human types. III and V. Other chapters consider the FACIT collagen gene family. This book discusses as well the development in understanding the structure of small proteoglycan core proteins and their role in proteoglycan biosynthesis and function as a result of their molecular cloning and expression. The final chapter deals with mutations in collagen genes. This book is a valuable resource for biochemists.



Extracellular Matrix Influences On Gene Expression


Extracellular Matrix Influences On Gene Expression
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Author : Harold Slavkin
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Extracellular Matrix Influences On Gene Expression written by Harold Slavkin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.


Extracellular Matrix Influences on Gene Expression emerged from the Second international Santa Catalina Island Colloquium that deals with the discussion on the advances in the molecular biology of extracellular matrices and the epigenetic influences on cell function. Topics discussed include morphological descriptions, genetics, teratology, collagen heterogeneity, and mineralization. The book's 12 chapters discuss the chromosomal and extrachromosomal influences upon transcription, translational and post-translational regulations during development, and regulation of extracellular matrix molecular biosynthesis. The book describes the regulation of tissue-specific collagen biosynthesis and the extracellular matrix macromolecules. It contains papers that explain the outer cell surface specificity and cell interactions. Because there are advances as well in other specific topics, such as the epithelial-masenchymal interactions and extracellular matrix influences on gene expression, this book contains papers that deal with these subject matters. Furthermore, it explains the matrix-cell and cell-matrix interactions and mineralization processes, as well as the aberrations in developmental processes. This book will be useful to those individuals who study the scientific advances in developmental biology.



Organization And Assembly Of Plant And Animal Extracellular Matrix


Organization And Assembly Of Plant And Animal Extracellular Matrix
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Author : W. Steven Adair
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Organization And Assembly Of Plant And Animal Extracellular Matrix written by W. Steven Adair and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Organization and Assembly of Plant and Animal Extracellular Matrix presents a state-of-the-art view of some of the experimental systems in plant and animal matrix biology. It discusses certain principles underlying establishment of complex three-dimensional architecture cross broad evolutionary boundaries. The opening chapter reviews studies on the cellular mechanisms responsible for storage, release, assembly, and function of extracellular matrices during early sea urchin development. The subsequent chapters describe the structure, assembly, disassembly, and molecular biology of the Chlamydomonas reinhardtii cell wall. The chapters also summarize the status of work on basement membrane assembly. Important insights into approaches to identify critical molecular domains and the complexity of relating defined molecular associations to establishment of matrix architecture are provided. A family of discovered cell wall genes that encode protein products containing up to 70% glycine is presented in Chapter 4. This is followed by a discussion on the role of alginate self-assembly in cell wall formation in Fucus. The book goes on to address the issue of protein-carbohydrate recognition with a detailed discussion of plant and animal lectins. Chapter 7 tackles a family of genes encoding higher plant hydroxyproline-rich glycoproteins (HRGPs) and the relationship between the HRGP genes cloned and their products. The final two chapters are devoted to one of the most important classes of protein modifying enzymes for extracellular matrix formation and function, the prolyl hydroxylases. This book will be of help to workers in plant and animal matrix in understanding information, approaches, and ideas that they may not normally encounter.



Evolution Of Extracellular Matrix


Evolution Of Extracellular Matrix
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Author : Fred W. Keeley
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-15

Evolution Of Extracellular Matrix written by Fred W. Keeley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-15 with Science categories.


The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.



The Extracellular Matrix


The Extracellular Matrix
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Author : Davide Vigetti
language : en
Publisher:
Release Date : 2019

The Extracellular Matrix written by Davide Vigetti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biochemistry categories.


This volume details established experimental protocols on the isolation, characterization, and detection of extracellular matrix (ECM) molecules as well as methods to study the activity and role of ECM components on various biological functions, the formation of exosomes, and tissue surrogates. Chapters display a variety of protocols ranging from biochemical, cell, and molecular biology assays to complex tissue imaging techniques and in vivo models to elucidate the role of the extracellular matrix. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, The Extracellular Matrix: Methods and Protocols aims to provide protocols and applications that can be used by both Ph.D. students and senior researchers to advance research in the field of extracellular matrix biology.



Cell Biology Of Extracellular Matrix


Cell Biology Of Extracellular Matrix
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Author : Elizabeth D. Hay
language : en
Publisher:
Release Date : 1983

Cell Biology Of Extracellular Matrix written by Elizabeth D. Hay and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.




Cell Biology Of Extracellular Matrix


Cell Biology Of Extracellular Matrix
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Author : Elizabeth D. Hay
language : en
Publisher: Springer
Release Date : 2011-10-08

Cell Biology Of Extracellular Matrix written by Elizabeth D. Hay and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-08 with Science categories.


At a recent meeting to discuss the domains of cell biology, I put forth a case for the extracellular matrix, even though my argument ran the risk of falling on deaf ears. After all, the matrix is EXTRAcellular, outside the cells. In this book, however, the authors make a compelling case for the relevance of the matrix to cellular concerns. Not only are numerous cell types, including many epithelia, quite caught up in the business of manufacturing matrix components, but also most of them contain matrix molecules in exoskeletons that are attached to the plasmalemma and that organize or otherwise influence the affairs of the cyto plasm. The idea of this book is to present the extracellular matrix to cell biolo gists of all levels. The authors are active and busy investigators, recognized experts in their fields, but all were enthusiastic about the prospect of writing for this audience. The chapters are not "review" articles in the usual sense, nor are they rehashes of symposium talks; they were written specifically for this book and they present the "state of the art" in engaging style, with ample references to more technical or historical reviews. The book is rich in electron micro graphs and diagrams and for many of the latter, as well as for the design of the cover, we are indebted to Sylvia J. Keene, medical illustrator for the Department of Anatomy at Harvard Medical Scrool. We also owe special thanks to Susan G.



Molecular Biophysics Of The Extracellular Matrix


Molecular Biophysics Of The Extracellular Matrix
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Author : Struther Arnott
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Molecular Biophysics Of The Extracellular Matrix written by Struther Arnott and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.