The Control Of Physiological Programmed Cell Death
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The Control Of Physiological Programmed Cell Death
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Author : Angus Crawford Cameron
language : en
Publisher:
Release Date : 1991
The Control Of Physiological Programmed Cell Death written by Angus Crawford Cameron and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Apoptosis categories.
Cell Apoptosis
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Author : Lawrence B. Shultz
language : en
Publisher: Nova Publishers
Release Date : 2007
Cell Apoptosis written by Lawrence B. Shultz and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Apoptosis categories.
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer.A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book deals with cell apoptosis regulation and environmental factors.
Mechanisms Of Lymphocyte Activation And Immune Regulation Vi
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Mechanisms Of Lymphocyte Activation And Immune Regulation Vi written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Since programmed cell death was first described in insects in 1964 and apoptosis was described in 1972, rapid progress has been made in understanding the basic mechanisms and genes regulating programmed cell death and apoptosis. In addition, defects in various genes regulating programmed cell death have been delineated in several experimental models of human diseases. This volume surveys various aspects of these rapidly developing areas of research in programmed cell death/apoptosis. This volume should be of interest to basic immunologists and molecular biologists. The volume begins with a historical perspective of cell death. The remainder of the volume is divided into four different parts. Part I deals with the signaling pathways in apoptosis, including cell cycle control of apoptosis, role of ceramide in apoptosis, role of antibody signaling, and biochemical regulation of apoptosis. The mechanisms for recognition of apoptotic lymphocytes by macrophages are also reviewed. Part II examines the role of various genes that regulate apoptosis, including the role ofFas, FasL, and other TNF family members in apoptosis and homeostatic regulation of immune response. Recently described splice variants and their influence on apoptosis are also reviewed, and the role of the members of the Bcl-2 family in apoptosis is discussed in detail. Part III reviews various aspects of apoptosis in B lymphocytes, including mechanisms that regulate apoptosis/survival of B lymphocytes and the regulation of Fas-mediated apoptosis in B lymphocytes.
Cellular Aging And Cell Death
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Author : Nikki J. Holbrook
language : en
Publisher: John Wiley & Sons
Release Date : 1995-12-20
Cellular Aging And Cell Death written by Nikki J. Holbrook and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-12-20 with Science categories.
Cellular AGING AND CELL DEATH Edited by Nikki J. Holbrook, George R. Martin, and Richard A.Lockshin Cellular Aging and Cell Death provides a thorough understanding ofthe mechanisms responsible for cellular aging, covering the recentresearch on programmed cell death and senescence, and describingtheir role in the control of cell proliferation and the agingprocess. This one-of-a-kind book is the first to combine the twohottest research areas of cell biology into one comprehensivetext. Leading experts contribute to give readers an authoritativeoverview of the distinct fields of cellular aging and programmedcell death, as well as to demonstrate how both fields are criticalto understanding the aging process. They address the large andgrowing interest in apoptosis, especially with regard to themolecular signals that induce and regulate programmed cell death,and the role of apoptosis in a variety of age-associated diseasesand disabilities. Throughout the book, a strong emphasis is placedon the interrelationship of the molecular, cellular, andphysiological aspects of senescence. Individual chapters discuss such topics as the role and regulationof apoptosis in development, the potential impact of cell death onsuch postmitotic tissues as nerve and muscle, and suggest thatprogrammed cell death plays an important role in both pathologicaland nonpathological aspects of aging, including neurodegenerativediseases. One important chapter focuses on the most recent research involvingthe study of telomeres, whose reduction in length with age and celldivision may underlie cellular senescence. The subject of neuronalcell death is also put into the perspective of aging. Cellular Aging and Cell Death bridges the rapidly growing fields ofcellular aging and programmed cell death. This thorough, yetconcise book will be of particular interest to graduate studentsand researchers within the fields of cell and developmentalbiology, neurobiology, immunology, and physiology. Physicians andmedical students involved in the fields of gerontology andpathology will also find this an informative reference.
Apoptosis
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Author : Michael D. Jacobson
language : en
Publisher: Frontiers in Molecular Biology
Release Date : 2002
Apoptosis written by Michael D. Jacobson and has been published by Frontiers in Molecular Biology this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
The number of cells within the human body is very tightly regulated: too many and we can develop cancer, too few and we may lose cells that we cannot replace. The number of cells is controlled by several different mechanisms in different tissues, but all are triggered to commit suicide should too many be in one place at one time, or become damaged. This book examines how this process of cell suicide (apoptosis) is regulated, and how our understanding of this process may lead to novel treatments for a wide variety of human diseases.
Apoptosis
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Author : Douglas R. Green
language : en
Publisher: Cambridge University Press
Release Date : 2011-08-22
Apoptosis written by Douglas R. Green and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-22 with Science categories.
Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.
Cell Death In Reproductive Physiology
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Author : Jonathan L. Tilly
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cell Death In Reproductive Physiology written by Jonathan L. Tilly and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The regulation of cell death in various reproductive tissues, as in other ma jor organ systems of the body, has become a focal point of research activity in many laboratories over the past few years. As such, the need for a "for mal" meeting to highlight recent work in this field, as well as to integrate knowledge from other sources (such as investigators working on cell death in cancer and immune function) in the broad context of identifying con served pathways that coordinate life-and-death decisions in diverse cell types, became apparent. Therefore, the goals of the Scientific Committee of the International Symposium on Cell Death in Reproductive Physiology, spon sored by Serono Symposia USA, were already predetermined by this need. Simply stated, we sought to bring together for the first time a select cohort of reproductive biologists and cell death researchers, many but not all cho sen based on their pioneering efforts in elucidating the fundamental aspects of apoptosis in reproductive and nonreproductive tissues, as a means to re view the current status of the field, foster new ideas, and promote scientific collaborations. In the ensuing chapters of this book, summaries of work dis cussed at the meeting are presented to emphasize both the diversity and the similarities in the occurrence and regulation of apoptosis in tissues of the male and female reproductive systems.
Cell Death Proteins
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Author :
language : en
Publisher: Academic Press
Release Date : 1997-07-04
Cell Death Proteins written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-07-04 with Science categories.
Cell death is one of the fundamental processes by which normal development is modulated, and the importance of both necrosis and apoptosis in a number of pathologies has generated intense interest from researchers in many fields. This timely book covers both the proteins that are produced by dying cells and the proteins that signal cells to initiate cell death. Cell Death Proteins provides an overview of the explosive interest in cellular death. Six review papers, written by researchers at the forefront of this rapidly moving field, focus on proteins that promote, signal, and inhibit cell death. Major players involved in the cell death cascade and its controls are covered, including cell cycle checkpoints, the function of interleukin-1J converting enzyme, the role of IGF-I receptor, the Bcl-2 family of proteins, viral inhibitors of apoptosis, and p53-dependent apoptosis.
Programmed Cell Death In Plants And Animals
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Author : Josephine Rice
language : en
Publisher: Nova Science Publishers
Release Date : 2016
Programmed Cell Death In Plants And Animals written by Josephine Rice and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Science categories.
Both autophagy and programmed cell death (PCD) are fundamental processes of cellular maintenance that are closely interrelated in plant and animal cells under physiological and stressful conditions. Differentiation, immune response, lack of nutrients, and wide range of abiotic factors induce their development and realization of survival or cell death scenario. Microtubular cytoskeleton is known as one of the principle players in the mediation of PCD/autophagic signals. Chapter One in this book presents an overview of the current knowledge about the role of MTs in PCD- and autophagy-related processes in plants. Chapter Two reviews the mechanisms and consequences of virus interactions with the hotel cell-death machinery, to help understand potentially pathologically relevant consequences that will help in the design of intervention strategies and the development of antiviral therapies. The final chapter discusses the control of the levels of different reactive oxygen species (ROS) and their interaction with hormones and transcriptional factors in relation with programmed cell death in leaves.
Programmed Cell Death
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Author : Roya Khosravi-Far
language : en
Publisher: Academic Press
Release Date : 2008-08-28
Programmed Cell Death written by Roya Khosravi-Far and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-08-28 with Science categories.
The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (UK),H. Robert Horvitz (US)and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. *Provides the necessary, trusted methods to carry out this research on the latest techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies *Presents key methods on studying tumors and how these cancer cells evade cell death *Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over