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The Dopaminergic System


The Dopaminergic System
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Dopaminergic System Function And Dysfunction Experimental Approaches


Dopaminergic System Function And Dysfunction Experimental Approaches
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Author : José Antonio Fuentealba-Evans
language : en
Publisher: Springer Nature
Release Date : 2022-12-07

Dopaminergic System Function And Dysfunction Experimental Approaches written by José Antonio Fuentealba-Evans and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-07 with Medical categories.


This volume provides a variety of technical approaches to study dopamine system function and dysfunction. Chapters guide readers through dopamine release in ex vivo and freely moving animals, multi-recording devices for in vivo simultaneous single cell and population activity, in silico modeling of dopamine neurons activity, neuroanatomical approaches, unbiased stereology, ultrastructural analyses of dopaminergic neurons, and axonal innervation. Additionally, chapters also incorporate pharmacological tools to model neuropsychiatric diseases, novel behavioral paradigms to dissect dopamine's role in behavior, and functional imaging to follow human dopamine system development. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Dopamine Neurotransmission aims to be a valuable resource for researchers in various disciplines.



Brain Dopaminergic Systems Imaging With Positron Tomography


Brain Dopaminergic Systems Imaging With Positron Tomography
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Author : J.C Baron
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Brain Dopaminergic Systems Imaging With Positron Tomography written by J.C Baron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Imaging of the Dopaminergic system in the human brain with the in vivo use of Positron Emis sion Tomography has emerged in the late 1980s as a tool of major importance in Clinical Neuros ciences and Pharmacology. The last few years have witnessed the rapid development of new radiotracers specific to receptors, reuptake sites and enzymes of the dopamine system; the application of these radiotracers has led to major breakthroughs in the pathophysiology and therapy of movement disorders and schizophrenic-like psychoses. This book is the first to collect, in a single volume, state-of-the-art contributions to the various aspects of this research. Its contents address methodological issues related to the design, labelling, quantitative imaging and compartmental modelisation of radioligands of the post-synaptic, pre-synaptic and enzyme sites of the dopamine system and to their use in clinical research in the fields of Parkinson's disease as well as other movement disorders, psychoses and neuroleptic receptor occupancy. The chapters were written by leading European scientists in the field of Positron Emission Tomography, gathered together in Caen (France, November 1990) under the aegis of the EEC Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration. This book provides a current and comprehensive overview on PET studies of the brain dopamine system which should aid and interest neurologists, psychiatrists, pharmacologists and medical imaging scientists. J.C. Baron D. Comar L. Farde J.L. Martinot B. Mazoyer August 1991 ix LIST OF CONTRffiUTORS Dr Yves Agid DrL.



The Dopaminergic System


The Dopaminergic System
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Author : Béla Halász
language : en
Publisher: Springer Verlag
Release Date : 1985-01-01

The Dopaminergic System written by Béla Halász and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-01-01 with Dopamine categories.




Brain Dopaminergic Systems


Brain Dopaminergic Systems
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Author : European Economic Community
language : en
Publisher: Springer Science & Business Media
Release Date : 1991

Brain Dopaminergic Systems written by European Economic Community and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


.the book is most valuable for those who are starting to study the brain dopaminergic system and are considering PET as a tool.' Nuclear Medicine 19:9 1992



Dopaminergic Systems And Their Regulation


Dopaminergic Systems And Their Regulation
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Author : Geoffrey N. Woodruff
language : en
Publisher:
Release Date : 1986

Dopaminergic Systems And Their Regulation written by Geoffrey N. Woodruff and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Dopamine categories.




The Dopaminergic System


The Dopaminergic System
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Author : Edward W. Flückiger
language : en
Publisher:
Release Date : 1981

The Dopaminergic System written by Edward W. Flückiger and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with categories.




The Dopaminergic System


The Dopaminergic System
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Author : B Halasz
language : en
Publisher:
Release Date : 1985-09-01

The Dopaminergic System written by B Halasz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-09-01 with categories.




Dopaminergic System


Dopaminergic System
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Author : Liana Bolis
language : en
Publisher:
Release Date : 2001

Dopaminergic System written by Liana Bolis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.


In this volume an international, multidisciplinary group of experts reviews the latest findings on the biology of dopaminergic neurotransmission and the role of dopamine in the pathophysiology and treatment of disorders such as schizophrenia, depression, dysthymia, and motor diseases. The book integrates current knowledge on dopaminergic function from diverse areas of basic science and clinical research, including molecular biology, transgenic studies, biochemistry, genetics, brain imaging, neurology, and psychiatry.



The Dopaminergic System In The Hippocampal Formation Of The Macaca Fascicularis Monkey


The Dopaminergic System In The Hippocampal Formation Of The Macaca Fascicularis Monkey
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Author : Mirela Loftus
language : en
Publisher:
Release Date : 2001

The Dopaminergic System In The Hippocampal Formation Of The Macaca Fascicularis Monkey written by Mirela Loftus and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with English drama categories.




Development And Engineering Of Dopamine Neurons


Development And Engineering Of Dopamine Neurons
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Author : Jeroen Pasterkamp
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-16

Development And Engineering Of Dopamine Neurons written by Jeroen Pasterkamp and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-16 with Medical categories.


Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.