The Experimental Foundations Of Modern Immunology
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The Experimental Foundations Of Modern Immunology
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Author : William R. Clark
language : en
Publisher: John Wiley & Sons
Release Date : 1983
The Experimental Foundations Of Modern Immunology written by William R. Clark and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
At War Within
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Author : William R. Clark
language : en
Publisher: Oxford University Press
Release Date : 1995-11-30
At War Within written by William R. Clark and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-11-30 with Medical categories.
In the seventeenth century, smallpox reigned as the world's worst killer. Luck, more than anything else, decided who would live and who would die. That is, until Lady Mary Wortley Montagu, an English aristocrat, moved to Constantinople and noticed the Turkish practice of "ingrafting" or inoculation, which, she wrote, made "the small- pox...entirely harmless." Convinced by what she witnessed, she allowed her six-year-old son to be ingrafted, and the treatment was a complete success--the young Montagu enjoyed lifelong immunity from smallpox. Lady Montagu's discovery would, however, remain a quiet one; it would be almost 150 years before inoculation (in the more modern form of vaccination) would become widely accepted while the medical community struggled to understand the way our bodies defend themselves against disease. William Clark's At War Within takes us on a fascinating tour through the immune system, examining the history of its discovery, the ways in which it protects us, and how it may bring its full force to bear at the wrong time or in the wrong place. Scientists have only gradually come to realize that this elegant defense system not only has the potential to help, as in the case of smallpox, but also the potential to do profound harm in health problems ranging from allergies to AIDS, and from organ transplants to cancer. Dr. Clark discusses the myriad of medical problems involving the immune system, and he systematically explains each one. For example, in both tuberculosis and AIDS, the underlying pathogens take up residence within the immune system itself, something Clark compares to having a prowler take up residence in your house, crawling around through the walls and ceilings while waiting to do you in. He discusses organ transplants, showing how the immune system can work far too well, and touching on the heated ethical debate over the use of both primate and human organs. He explores the mind's powerful ability to influence the performance of the immune system; and the speculation that women, because they have developed more powerful immune systems in connection with childbearing, are more prone than men to contract certain diseases such as lupus. In a fascinating chapter on AIDS, arguably the most deadly epidemic seen on Earth since the smallpox, Clark explains how the disease originated and the ways in which it operates. And, in each section, we learn about the most recent medical breakthroughs. At first glance, it may appear that our immune system faces daunting odds; it must learn to successfully fend off, not thousands, but millions of different types of microbes. Fortunately, according to Clark, it would be almost impossible to imagine a more elegant strategy for our protection than the one chosen by our immune system, and his At War Within provides a thorough and engaging explanation of this most complex and delicately balanced mechanism.
Paul Ehrlich S Receptor Immunology
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Author : Arthur M. Silverstein
language : en
Publisher: Elsevier
Release Date : 2001-11-17
Paul Ehrlich S Receptor Immunology written by Arthur M. Silverstein and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-17 with Medical categories.
Paul Ehrlich's Receptor Immunology: The Magnificent Obsession describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field. The selectionist theory of antibody formation Kinetics of primary and secondary antibody response Quantitative methods of measurement of antigens and antibody Demonstration of passive transfer of immunity from mother to foetus
The Foundations Of Immunology And Their Pertinence To Medicine
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Author : Peter Bretscher
language : en
Publisher: FriesenPress
Release Date : 2016-12-05
The Foundations Of Immunology And Their Pertinence To Medicine written by Peter Bretscher and has been published by FriesenPress this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-12-05 with categories.
In The Foundations of Immunology and their Pertinence to Medicine, Peter Bretscher describes how the few foundational concepts of immunology came about. He traces Jenner's development of safe vaccination against small pox in the 1700's, and how it led to the recognition of infectious disease by Koch and Pasteur in the 1880's, and to the discovery of the Principles of Vaccination. The formulation of the Clonal Selection Theory in the 1950's still provides a foundation for contemporary analysis of the immune system. Peter describes the main, and sometimes conflicting concepts, proposed in the last 50 years as to how immune responses are regulated. He develops a unique framework, and employs this to justify some tested and some speculative strategies to prevent and treat clinical conditions in five areas of medicine: Infectious Diseases, Cancer, Autoimmunity, Allergies and Transplantation. This book provides a platform for discussing contemporary immunological issues accessible to the non-specialist, medical students and medical practitioners. The platform challenges some of todays most popular paradigms. Foundations is written in a clear and jargon-free style.
A History Of Modern Immunology
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Author : Zoltan A. Nagy
language : en
Publisher: Academic Press
Release Date : 2013-10-11
A History Of Modern Immunology written by Zoltan A. Nagy and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-11 with Medical categories.
A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries. Contains the history of major breakthroughs in immunology featured with authenticity and insider details Gives an insight into personal aspects of the players in the history of immunology Enables the reader to recognize and select data of heuristic value which elucidate important facets of the immune system Provides good examples and guidelines for the recognition and selection of what is important for the exploration of the immune system Gives clear separation of descriptive and interpretive parts, allowing the reader to distinguish between facts and analysis provided by the author
Experimental Immunology
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Author : Francis J. DeToma
language : en
Publisher: Macmillan Publishing Company
Release Date : 1987
Experimental Immunology written by Francis J. DeToma and has been published by Macmillan Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Immunology categories.
Comparative Pathobiology Of Viral Diseases
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Author : Richard G. Olsen
language : en
Publisher: CRC Press
Release Date : 2019-08-15
Comparative Pathobiology Of Viral Diseases written by Richard G. Olsen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-15 with Science categories.
First Published in 1985, this book offers a full insight into the differences and similarities between varying diseases. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine and other practitioners in their respective fields.
Systems Immunology
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Author : Jayajit Das
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Systems Immunology written by Jayajit Das and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Science categories.
"Taken together, the body of information contained in this book provides readers with a bird’s-eye view of different aspects of exciting work at the convergence of disciplines that will ultimately lead to a future where we understand how immunity is regulated, and how we can harness this knowledge toward practical ends that reduce human suffering. I commend the editors for putting this volume together." –Arup K. Chakraborty, Robert T. Haslam Professor of Chemical Engineering, and Professor of Physics, Chemistry, and Biological Engineering, Massachusetts Institute of Technology, Cambridge, USA New experimental techniques in immunology have produced large and complex data sets that require quantitative modeling for analysis. This book provides a complete overview of computational immunology, from basic concepts to mathematical modeling at the single molecule, cellular, organism, and population levels. It showcases modern mechanistic models and their use in making predictions, designing experiments, and elucidating underlying biochemical processes. It begins with an introduction to data analysis, approximations, and assumptions used in model building. Core chapters address models and methods for studying immune responses, with fundamental concepts clearly defined. Readers from immunology, quantitative biology, and applied physics will benefit from the following: Fundamental principles of computational immunology and modern quantitative methods for studying immune response at the single molecule, cellular, organism, and population levels. An overview of basic concepts in modeling and data analysis. Coverage of topics where mechanistic modeling has contributed substantially to current understanding. Discussion of genetic diversity of the immune system, cell signaling in the immune system, immune response at the cell population scale, and ecology of host-pathogen interactions.
Handbook Of Experimental Immunology Immunochemistry
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Author : Donald Mackay Weir
language : en
Publisher:
Release Date : 1986
Handbook Of Experimental Immunology Immunochemistry written by Donald Mackay Weir and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Experimental immunology categories.
Infection Resistance And Immunity Second Edition
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Author : Julius Kreier
language : en
Publisher: Taylor & Francis
Release Date : 2022-04-18
Infection Resistance And Immunity Second Edition written by Julius Kreier and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-18 with Medical categories.
Designed as an introductory textbook, Infection, Resistance and Immunity provides basic information on the workings of the immunological system and on infectious processes and their control. With sections on immunological disorders, immunization, immunodiagnosis, and epidemiology, it relates immunology to practical problems in medicine. The book includes a section on comparative immunology, introducing students to differences among immunological systems among common species of nonhuman animals. Written for the advanced undergraduate, the focus is on host-parasite interactions—distinguishing this text from other standard texts, which focus on the cellular mechanisms of the immune response.