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The Extracellular Matrix Factsbook

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The Extracellular Matrix Factsbook

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Author : Shirley Ayad
language : en
Publisher: Elsevier
Release Date : 1998-03-27

The Extracellular Matrix Factsbook written by Shirley Ayad and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-03-27 with Science categories.

The Second Edition of The Extracellular Matrix FactsBook has been completely revised, updated and expanded by over 50 percent. It contains over 85 entries on the diverse group of macromolecules that assemble toform the extracellular matrix. Entries provide information on molecular structure, isolation, primary structure, structural and functional sites, gene structure, database accession numbers, and key references. Key Features * Compiled by members of one of the foremost centers of matrix biochemistry in the world * Contains over 30 new entries, with all previous entries being revised and updated * Includes new entries on proteinases involved in the deposition of the extracellular matrix * Presents 3D ribbon diagrams in cases where the protein structure is now known

The Extracellular Matrix Factsbook

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Author : Shirley Ayad
language : en
Publisher:
Release Date : 1998

The Extracellular Matrix Factsbook written by Shirley Ayad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Electronic books categories.

Cell Biology Of Extracellular Matrix

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Author : E.D. Hay
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Cell Biology Of Extracellular Matrix written by E.D. Hay and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.

In the ten-year interval since the first edition of this volume went to press, our knowledge of extracellular matrix (ECM) function and structure has enor mously increased. Extracellular matrix and cell-matrix interaction are now routine topics in the meetings and annual reviews sponsored by cell biology societies. Research in molecular biology has so advanced the number of known matrix molecules and the topic of gene structure and regulation that we won dered how best to incorporate the new material. For example, we deliberated over the inclusion of chapters on molecular genetics. We decided that with judicious editing we could present the recent findings in molecular biology within the same cell biology framework that was used for the first edition, using three broad headings: what is extracellular matrix, how is it made, and what does it do for cells? Maintaining control over the review of literature on the subject of ECM was not always an easy task, but we felt it was essential to production of a highly readable volume, one compact enough to serve the the student as an introduction and the investigator as a quick update on graduate the important recent discoveries. The first edition of this volume enjoyed con hope the reader finds this edition equally useful. siderable success; we D. Hay Elizabeth vii Contents Introductory Remarks 1 Elizabeth D. Hay PART I. WHAT IS EXTRACELLULAR MATRIX? Chapter 1 Collagen T. F. Linsenmayer 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. The Collagen Molecule . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 2. 1. Triple-Helical Domain(s) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

The Extracellular Matrix An Overview

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Author : Robert Mecham
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-02-16

The Extracellular Matrix An Overview written by Robert Mecham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-02-16 with Science categories.

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.

Extracellular Matrix

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Author : M. A. Haralson
language : en
Publisher: Oxford University Press
Release Date : 1995

Extracellular Matrix written by M. A. Haralson and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Literary Criticism categories.

Studies of the extracellular matrix (the material that surrounds cells and tissues) span much of modern biological research. In addition to providing structure to organisms the extracellular matrix is crucial in determining cell growth, how the cell responds during injury and development and what the cell makes. Changes in the extracellular matrix are important components in both inherited and acquired diseases such as diabetes and cancer. This important volume brings together undera single cover the majority of techniques currently employed in extracellular matrix research and will serve as an indispensable resource for researchers and clinicians in this field.

Extracellular Matrix Biology

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Author : Richard O. Hynes
language : en
Publisher:
Release Date : 2012

Extracellular Matrix Biology written by Richard O. Hynes and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Cell interaction categories.

In most tissues, cells are surrounded by an extracellular matrix (ECM) containing proteins such as collagen, laminin, and fibronectin. The ECM plays an important role in regulating cell function. ECM proteins bind to integrins and other cell surface receptors, activating signaling pathways that regulate cellular morphology, adhesion, cell migration, cell proliferation, and apoptosis. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of ECM composition and function, as well as alterations in the ECM that occur during development, tumorigenesis, and other disease states. The contributors examine the various ECM proteins and proteoglycans, ECM receptors such as integrins, and the signaling pathways that mediate the effects of the ECM on cells. They also describe ECM functions in specific biological contexts, including angiogenesis, hemostasis, and thrombosis. Covering not only the biochemistry and cell biology of the ECM but also its roles in development, physiology, and pathology, this volume is an indispensable reference for cell biologists and all those interested in exploring the myriad functions of the ECM.