The Fungal Cell Wall Integrity Pathway
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The Fungal Cell Wall Integrity Pathway
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Author : María Molina
language : en
Publisher: Mdpi AG
Release Date : 2023-03-17
The Fungal Cell Wall Integrity Pathway written by María Molina and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-17 with Science categories.
Adaptation to external changes is necessary for all cells to survive and thrive in diverse environments. Key to these responses are the MAPK-mediated signaling pathways, intracellular communication routes that sense stimuli at the cell surface, and are ubiquitous in all eukaryotic organisms. In the case of fungi, MAPKs mediate essential processes, such as adaptation to environmental stresses, morphology regulation, or developmental processes. First studied in the early nineties in Saccharomyces cerevisiae, the fungal cell wall integrity (CWI) pathway has proven to be a central MAPK-mediated signaling cascade conserved in the fungal kingdom. Cells need to sense cell wall-perturbing conditions and mount the appropriate salvage response. Understanding this CWI pathway-mediated compensatory mechanism is key for the development of cell wall-targeted antifungal therapies. Moreover, its functional roles go beyond the maintenance of this essential structure, reaching many other physiological aspects that have major implications in development or virulence. In this Special Issue, expert researchers in this relevant subject have contributed with seven reviews and eleven original articles to advance our understanding of the CWI pathway by covering different structural, regulatory, and functional aspects in distinct yeasts and filamentous fungi.
The Fungal Cell Wall
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Author : Fausto Almeida
language : en
Publisher: Frontiers Media SA
Release Date : 2020-11-19
The Fungal Cell Wall written by Fausto Almeida and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-19 with Science categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
The Fungal Cell Wall
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Author : Jean-Paul Latgé
language : en
Publisher: Springer Nature
Release Date : 2020-08-12
The Fungal Cell Wall written by Jean-Paul Latgé and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-12 with Science categories.
This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the composition of the fungal cell wall is a unique structure, which cannot be found in the human host. Consequently, the chapters outline, how the immune systems of both animals and humans have evolved to recognize conserved and unique elements of the fungal cell wall. As an application example, the authors also show, that the three-dimensional structures of the cell wall are excellent targets for the development of antifungal agents and chemotherapeutic strategies. With the combination of biological findings and medical outlooks, this volume is a fascinating read for scientists, clinicians and biomedical students.
The Role Of The Fungal Cell Wall In Host Fungal Interactions
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Author : Vishukumar Aimanianda
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-17
The Role Of The Fungal Cell Wall In Host Fungal Interactions written by Vishukumar Aimanianda and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-17 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Fungal Cell Wall
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Author : José Ruiz-Herrera
language : en
Publisher: CRC Press
Release Date : 2012-05-01
Fungal Cell Wall written by José Ruiz-Herrera and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-01 with Science categories.
Fungal Cell Wall: Structure, Synthesis, and Assembly, Second Edition is a compendium of information on the chemical structure, synthesis, and organization of the cell wall of fungi. Reviewing the past 20 years of research in the field, it discusses experimental evidence that demonstrates the role of the cell wall in the growth, development, morphogenesis, and evolution of fungi. Synthesizes 20 Years of Important Research on Fungal Cell Walls More than just a revision, this second edition offers a fresh perspective on what is currently known about the fungal cell wall. It covers recent developments, conflicting theories, and important aspects that are largely forgotten—including critical analysis of the prevalent idea that cell walls from all fungal species have the same basic structure, organization, and behavior as the most popular models of study. Chapters are self-contained and can be read independently, allowing readers to delve into specific topics. The book begins by examining the chemical composition and structure of the fungal cell wall, an area almost closed to modern research. It then describes the structure and synthesis of the most important components of the cell wall and analyzes the mechanisms of cell wall expansion and growth. Throughout, the book identifies the basic concepts that have led to modern ideas about cell walls. The Essential Guide to the Fungal Cell Wall A critical review of fungal cell wall research, this book helps readers understand the role of fungi in nature—both positive and negative—from their symbiotic associations and biotechnological applications to their pathogenicity to plants, animals, and humans.
Fungal Cell Wall And Immune Response
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Author : J.P. Latge
language : en
Publisher: Springer
Release Date : 2014-01-13
Fungal Cell Wall And Immune Response written by J.P. Latge and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-13 with Medical categories.
Recent findings on the role of the cell wall of pathogenetic fungi in the pathogenic processes of both vertebrates and invertebrates are presented. The fungal cell wall not only gives shape to the fungus, but it is a dynamic structure allowing fungal growth and survival of fungi in both friendly and adverse environments. It acts as a living sieve controlling the entry of nutrients and the secretion of metabolic products. In terms of fungal pathogenesis, the fungal wall may be responsible for eliciting the defense response of their respective invertebrate or vertebrate hosts or conversely it may provide protection against the host defense system during the pathogenic process.
Fungal Cell Wall
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Author : José Ruiz-Herrera
language : en
Publisher: CRC Press
Release Date : 1991-11-22
Fungal Cell Wall written by José Ruiz-Herrera and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-11-22 with Science categories.
Fungal Cell Wall presents a comprehensive examination of the structure, synthesis, and growth of the fungal cell wall and explores the reasons for the cell wall's importance to the survival of fungi. Topics covered include the composition and structure of the fungal cell wall and how they are affected by endogenous and external factors; the structure and synthesis of glucans, chitin, and glycoproteins; and the mechanisms of secretion, organization, and final assembly of the cell wall components. The book also features excellent bibliographical coverage, which provides insight into the historical development of current ideas and the basis of current trends in research. Researchers and students in biology, microbiology, mycology, botany, and medical and plant pathology will find this book essential for reference information regarding fungi.
Biology Of The Fungal Cell
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Author : Richard J. Howard
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-06-30
Biology Of The Fungal Cell written by Richard J. Howard and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-06-30 with Science categories.
What makes the fungal cell unique among eukaryotes and what features are shared? This volume addresses some of the most prominent and fascinating facets of questions as they pertain to the growth and development of both yeast and hyphal forms of fungi, beginning with subcellular components – then cell organization, polarity, growth, differentiation and beyond – to the cell biology of spores, biomechanics of invasive growth, plant pathogenesis, mycorrhizal symbiosis and colonial networks. Throughout, structural, molecular and ecological aspects are integrated to form a contemporary look at the biology of the fungal cell.
Clinical Mycology
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Author : Elias J. Anaissie
language : en
Publisher: Elsevier Health Sciences
Release Date : 2009-01-01
Clinical Mycology written by Elias J. Anaissie and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-01-01 with Medical categories.
The first book of its kind to focus on the diagnosis, prevention, and treatment of patients with fungal infections, this definitive reference returns in a completely revised, full-color new edition. It presents specific recommendations for understanding, controlling, and preventing fungal infections based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. More than 560 photographs, illustrations, and tables depict conditions as they appear in real life and equip you to identify clinical manifestations with accuracy. Expanded therapy content helps you implement the most appropriate treatment quickly, and a bonus CD-ROM-featuring all of the images from the text-enables you to enhance your electronic presentations. Includes specific recommendations for diagnosing, preventing, and treating fungal infections in various patient populations based upon underlying principles of epidemiology and infection control policy, pathogenesis, immunology, histopathology, and laboratory diagnosis and antifungal therapy. Covers etiologic agents of disease, fungal infections in special hosts such as pediatric patients and patients with cancer and HIV, infections of specific organ systems, and more, to make you aware of the special considerations involved in certain cases. Features clinically useful and reader-friendly practical tools-including algorithms, slides, graphs, pictorials, photographs, and radiographs-that better illustrate and communicate essential points, promote efficient use in a variety of clinical and academic settings, and facilitate slide making for lectures and presentations. Offers a CD-ROM containing all of the book's images for use in your electronic presentations. Offers more clinically relevant images-more than 300 in full color for the first time-to facilitate diagnosis. Features expanded therapy-related content, including up-to-date treatment strategies and drug selection and dosing guidelines. Includes several new sections in the chapter on fungal infections in cancer patients that reflect the formidable clinical challenges these infections continue to present. Presents the work of additional international contributors who have defined many of the key issues in the field, providing more of a global perspective on the best diagnostic and management approaches. Uses a new, full-color design to enhance readability and ease of access to information.
Biochemistry Of Cell Walls And Membranes In Fungi
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Author : Paul J. Kuhn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Biochemistry Of Cell Walls And Membranes In Fungi written by Paul J. Kuhn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Despite the many advances made during the last decade in various aspects of fungal biochemistry, there have been very few volumes devoted to the sub ject in recent years. This lack is all the more surprising in view of the increas ing use of fungi in gene manipulation studies and in biotechnological ap plications, and of the current interest in the biorational discovery of novel agents for the control of fungal pathogens of plants and humans. We hope that this book goes some way to rectifying this situation by providing an up to-date account of selected developments in two important areas, namely cell walls and membranes. Topics included in the book concern both yeasts and filamentous fungi. Although the main emphasis is on biogenesis, functional aspects are also discussed, e.g. the role of glycoproteins in recognition of sterols in mem branes and of calcium in regulation. Several contributions describe in terference with the 'normal' biochemistry of cell walls and membranes with a view to increasing fundamental knowledge, but also highly relevant to the design of new fungicides and antimycotics. The steadily increasing impact of molecular biology on the study of fungal biochemistry is highlighted throughout.