The Gene Ontology Handbook


The Gene Ontology Handbook
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The Gene Ontology Handbook


The Gene Ontology Handbook
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Author : Christophe Dessimoz
language : en
Publisher:
Release Date : 2020-10-08

The Gene Ontology Handbook written by Christophe Dessimoz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Science categories.


This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.



The Gene Ontology Handbook


The Gene Ontology Handbook
DOWNLOAD

Author : Christophe Dessimoz
language : en
Publisher:
Release Date : 2020-10-08

The Gene Ontology Handbook written by Christophe Dessimoz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Science categories.


This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.



Handbook Of Metadata Semantics And Ontologies


Handbook Of Metadata Semantics And Ontologies
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Author : Sicilia Miguel-angel
language : en
Publisher: World Scientific
Release Date : 2013-12-17

Handbook Of Metadata Semantics And Ontologies written by Sicilia Miguel-angel and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-17 with Computers categories.


Metadata research has emerged as a discipline cross-cutting many domains, focused on the provision of distributed descriptions (often called annotations) to Web resources or applications. Such associated descriptions are supposed to serve as a foundation for advanced services in many application areas, including search and location, personalization, federation of repositories and automated delivery of information. Indeed, the Semantic Web is in itself a concrete technological framework for ontology-based metadata. For example, Web-based social networking requires metadata describing people and their interrelations, and large databases with biological information use complex and detailed metadata schemas for more precise and informed search strategies.There is a wide diversity in the languages and idioms used for providing meta-descriptions, from simple structured text in metadata schemas to formal annotations using ontologies, and the technologies for storing, sharing and exploiting meta-descriptions are also diverse and evolve rapidly. In addition, there is a proliferation of schemas and standards related to metadata, resulting in a complex and moving technological landscape — hence, the need for specialized knowledge and skills in this area.The Handbook of Metadata, Semantics and Ontologies is intended as an authoritative reference for students, practitioners and researchers, serving as a roadmap for the variety of metadata schemas and ontologies available in a number of key domain areas, including culture, biology, education, healthcare, engineering and library science.



Biological Knowledge Discovery Handbook


Biological Knowledge Discovery Handbook
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Author : Mourad Elloumi
language : en
Publisher: John Wiley & Sons
Release Date : 2015-02-04

Biological Knowledge Discovery Handbook written by Mourad Elloumi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-04 with Computers categories.


The first comprehensive overview of preprocessing, mining,and postprocessing of biological data Molecular biology is undergoing exponential growth in both thevolume and complexity of biological data—and knowledgediscovery offers the capacity to automate complex search and dataanalysis tasks. This book presents a vast overview of the mostrecent developments on techniques and approaches in the field ofbiological knowledge discovery and data mining (KDD)—providingin-depth fundamental and technical field information on the mostimportant topics encountered. Written by top experts, Biological Knowledge DiscoveryHandbook: Preprocessing, Mining, and Postprocessing of BiologicalData covers the three main phases of knowledge discovery (datapreprocessing, data processing—also known as datamining—and data postprocessing) and analyzes both verificationsystems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological DataMining Combining sound theory with practical applications in molecularbiology, Biological Knowledge Discovery Handbook is idealfor courses in bioinformatics and biological KDD as well as forpractitioners and professional researchers in computer science,life science, and mathematics.



The Handbook Of Genetics Society


The Handbook Of Genetics Society
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Author : Paul Atkinson
language : en
Publisher: Routledge
Release Date : 2009-07-02

The Handbook Of Genetics Society written by Paul Atkinson and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-02 with Science categories.


An authoritative Handbook which offers a discussion of the social, political, ethical and economic consequences and implications of the new bio-sciences. The Handbook takes an interdisciplinary approach providing a synoptic overview of contemporary international social science research on genetics, genomics and the new life sciences. It brings together leading scholars with expertise across a wide-ranging spectrum of research fields related to the production, use, commercialisation and regulation of genetics knowledge. The Handbook is structured into seven cross-cutting themes in contemporary social science research on genetics with introductions written by internationally renowned section editors who take an interdisciplinary approach to offer fresh insights on recent developments and issues in often controversial fields of study. The Handbook explores local and global issues and critically approaches a wide range of public and policy questions, providing an invaluable reference source to a wide variety of researchers, academics and policy makers.



Gene Ontology A Resource For Analysis And Interpretation Of Biological Database


Gene Ontology A Resource For Analysis And Interpretation Of Biological Database
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Author : Paige Hill
language : en
Publisher:
Release Date : 2023-09-26

Gene Ontology A Resource For Analysis And Interpretation Of Biological Database written by Paige Hill and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Science categories.


The gene ontology (GO) is a bioinformatics project which aims to merge the representation of gene and characteristics of gene product in all species. It is a thorough and updated compilation of biological information that is utilized as a resource for computational representation of the most recent scientific data available concerning coding as well as non-coding functions of genes. High-throughput biological datasets can be interpreted and analyzed using the GO resource. The goal of the GO analysis is to pinpoint the molecular functions, biological processes and cellular locations of the genes. It utilizes markup language in order to make the genetic data and curated attributes of gene products readable by machine, in a manner which is integrated across all species. This book provides comprehensive insights on gene ontology. It aims to shed light on some of the unexplored aspects of this subject. Those in search of information to further their knowledge will be greatly assisted by this book.



Encyclopedia Of Bioinformatics And Computational Biology


Encyclopedia Of Bioinformatics And Computational Biology
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Author :
language : en
Publisher: Elsevier
Release Date : 2018-08-21

Encyclopedia Of Bioinformatics And Computational Biology written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-21 with Medical categories.


Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases



Handbook Of Hidden Markov Models In Bioinformatics


Handbook Of Hidden Markov Models In Bioinformatics
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Author : Martin Gollery
language : en
Publisher: CRC Press
Release Date : 2008-06-12

Handbook Of Hidden Markov Models In Bioinformatics written by Martin Gollery and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-12 with Science categories.


Demonstrating that many useful resources, such as databases, can benefit most bioinformatics projects, the Handbook of Hidden Markov Models in Bioinformatics focuses on how to choose and use various methods and programs available for hidden Markov models (HMMs). The book begins with discussions on key HMM and related profile methods, including the HMMER package, the sequence analysis method (SAM), and the PSI-BLAST algorithm. It then provides detailed information about various types of publicly available HMM databases, such as Pfam, PANTHER, COG, and metaSHARK. After outlining ways to develop and use an automated bioinformatics workflow, the author describes how to make custom HMM databases using HMMER, SAM, and PSI-BLAST. He also helps you select the right program to speed up searches. The final chapter explores several applications of HMM methods, including predictions of subcellular localization, posttranslational modification, and binding site. By learning how to effectively use the databases and methods presented in this handbook, you will be able to efficiently identify features of biological interest in your data.



Practical Guide To Life Science Databases


Practical Guide To Life Science Databases
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Author : Imad Abugessaisa
language : en
Publisher: Springer Nature
Release Date : 2022-01-06

Practical Guide To Life Science Databases written by Imad Abugessaisa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-06 with Science categories.


This book provides the latest information of life science databases that center in the life science research and drive the development of the field. It introduces the fundamental principles, rationales and methodologies of creating and updating life science databases. The book brings together expertise and renowned researchers in the field of life science databases and brings their experience and tools at the fingertips of the researcher. The book takes bottom-up approach to explain the structure, content and the usability of life science database. Detailed explanation of the content, structure, query and data retrieval are discussed to provide practical use of life science database and to enable the reader to use database and provided tools in practice. The readers will learn the necessary knowledge about the untapped opportunities available in life science databases and how it could be used so as to advance basic research and applied research findings and transforming them to the benefit of human life. Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.



Genetically Engineered Mice Handbook


Genetically Engineered Mice Handbook
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Author : John P. Sundberg
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Genetically Engineered Mice Handbook written by John P. Sundberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


While mice have always been highly popular laboratory subjects, their suitability for genetic engineering has solidified their position as today's lab animal model of choice. However, their increased use in genetic studies has created a demand for input on phenotyping that is not always easily met. To improve the flow of information on the pathology of mice with spontaneous or genetically engineered mutations, prominent researchers organized a series of meetings. Recognizing other needs, the organizers gradually broadened their focus, until finally they expanded to provide an overview of the entire field of genetically engineered models. The Genetically Engineered Mice Handbook is an extension of those meetings. It offers an introduction for those entering into this area of research, while also serving as a resource for those presently employing mice as laboratory models. Highly comprehensive, this volume covers pertinent aspects of genetically engineered mice, including the use of models for developmental biology and the monitoring of laboratory colonies. With contributions from nearly five-dozen leading researchers, the text presents systematic approaches for analyzing mutant mice for specific medical applications, details a variety of methods for creating mutants and includes information that is particularly hard to access dealing with legal responsibilities. This essential reference examines commonly used traditional, as well as emerging, technologies To address the purpose of the original meeting, the Genetically Engineered Mice Handbook directs researchers to the best public websites, and offers instruction on how to use them. In the past, as their work dictated, researchers would seek out experts on particular organ systems. Now groups of experts work together to generate these websites, providing the latest data as well as discussions over points of debate. These sites do not eliminate the need for a trained pathologist, but they do provide reference materials for those lacking expertise in particular anatomic structures. They also offer much greater numbers of examples than are available in print, from which biomedical researchers can draw.