The Geometry Of Genetics


The Geometry Of Genetics
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The Geometry Of Genetics


The Geometry Of Genetics
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Author : A. M. Findlay
language : en
Publisher: Wiley-Interscience
Release Date : 1989-03-20

The Geometry Of Genetics written by A. M. Findlay and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-03-20 with Mathematics categories.


Evolutionary biology has grown from the highly controversial world-view of the days of Charles Darwin, to a complex and refined theory of nature’s expression through the deep and subtle action of the genetic code. The Geometry of Genetics is an interdisciplinary monograph that presents the mathematical basis of molecular genetics, endowing evolutionary biology with a precision not before available to the subject. To make this work accessible to biologists and physical scientists alike, the authors have divided the subject into three parts, Structure, Statics, and Dynamics. Each of these parts is further subdivided into a presentation of the relevant mathematics, a description of the biological problem, and a mathematical reformulation of the biological problem. They provide, in effect, basic mathematical and biological primers for each topic covered. In the first part of the book, Statics, the authors develop some set-theoretic and linear algebraic notions, and describe the origin and evolution of the genetic code. Here they reveal the beauty of the hidden symmetries of the standard genetic code, and of their extension of genetic coding theory, the generalized genetic code. The second part of the book, Structure, expresses the basic processes of molecular genetics—replication, transcription, and translation—as operators on a certain linear space. The final part, Dynamics, realizes the action of molecular genetics as a differential geometry, within which evolutionary motions are treated as geodesics. It is here that evolutionary biology can be seen unfolding on the rich mathematical construct of a space-time manifold. This natural progression, from statics to structure and dynamics, provides a nested cohesiveness which reveals the intricate natural hierarchy of the elementary genetic code, molecular genetic action, and macromolecular evolution, which gives rise to a variety of genetic cosmologies. The Geometry of Genetics expresses the fundamental actions of evolutionary biology with a new richness and precision that should prove illuminating to biologists and physical scientists alike.



The Geometry Of Population Genetics


The Geometry Of Population Genetics
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Author : Ethan Akin
language : en
Publisher:
Release Date : 1979-11-01

The Geometry Of Population Genetics written by Ethan Akin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979-11-01 with categories.




Information Geometry And Population Genetics


Information Geometry And Population Genetics
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Author : Julian Hofrichter
language : en
Publisher: Springer
Release Date : 2017-02-23

Information Geometry And Population Genetics written by Julian Hofrichter and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-23 with Mathematics categories.


The present monograph develops a versatile and profound mathematical perspective of the Wright--Fisher model of population genetics. This well-known and intensively studied model carries a rich and beautiful mathematical structure, which is uncovered here in a systematic manner. In addition to approaches by means of analysis, combinatorics and PDE, a geometric perspective is brought in through Amari's and Chentsov's information geometry. This concept allows us to calculate many quantities of interest systematically; likewise, the employed global perspective elucidates the stratification of the model in an unprecedented manner. Furthermore, the links to statistical mechanics and large deviation theory are explored and developed into powerful tools. Altogether, the manuscript provides a solid and broad working basis for graduate students and researchers interested in this field.



Molecular Origins Of Brain And Body Geometry


Molecular Origins Of Brain And Body Geometry
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Author : Antonio Lima-de-Faria
language : en
Publisher: Springer
Release Date : 2014-10-07

Molecular Origins Of Brain And Body Geometry written by Antonio Lima-de-Faria and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-07 with Science categories.


New concepts arise in science when apparently unrelated fields of knowledge are put together in a coherent way. The recent results in molecular biology allow to explain the emergence of body patterns in animals that before could not be understood by zoologists. There are no ”fancy curiosities” in nature. Every pattern is a product of a molecular cascade originating in genes and a living organism arises from the collaboration of these genes with the outer physical environment. Tropical fishes are as startling in their colors and geometric circles as peacocks. Tortoises are covered with the most regular triangles, squares and concentric circles that can be green, brown or yellow. Parallel scarlet bands are placed side by side of black ones along the body of snakes. Zebras and giraffes have patterns which are lessons in geometry, with their transversal and longitudinal stripes, their circles and other geometric figures. Monkeys, like the mandrills, have a spectacularly colored face scarlet nose with blue parallel flanges and yellow beard. All this geometry turns out to be highly molecular. The genes are many and have been DNA sequenced. Besides they not only deal with the coloration of the body but with the development of the brain and the embryonic process. A precise scenario of molecular events unravels in the vertebrates. It may seem far-fetched, but the search for the origin of this geometry made it mandatory to study the evolution of matter and the origin of the brain. It turned out that matter from its onset is pervaded by geometry and that the brain is also a prisoner of this ordered construction. Moreover, the brain is capable of altering the body geometry and the geometry of the environment changes the brain. Nothing spectacular occurred when the brain arrived in evolution. Not only it came after the eye, which had already established itself long ago, but it had a modest origin. It started from sensory cells on the skin that later aggregated into clusters of neurons that formed ganglia. It also became evident that pigment cells, that decide the establishment of the body pattern, originate from the same cell population as neurons (the neural crest cells). This is a most revealing result because it throws light on the power that the brain has to rapidly redirect the coloration of the body and to change its pattern. Recent experiments demonstrate how the brain changes the body geometry at will and within seconds, an event that could be hardly conceived earlier. Moreover, this change is not accidental it is related to the surrounding environment and is also used as a mating strategy. Chameleons know how to do it as well as flat fishes and octopuses. No one would have dared to think that the brain had its own geometry. How could the external geometry of solids or other figures of our environment be apprehended by neurons if these had no architecture of their own? Astonishing was that the so called ”simple cells”, in the neurons of the primary visual cortex, responded to a bar of light with an axis of orientation that corresponded to the axis of the cell’s receptive field. We tend to consider our brain a reliable organ. But how reliable is it? From the beginning the brain is obliged to transform reality. Brain imagery involves: form, color, motion and sleep. Unintentionally these results led to unexpected philosophical implications. Plato’s pivotal concept that ”forms” exist independently of the material world is reversed. Atoms have been considered to be imaginary for 2,000 years but at present they can be photographed, one by one, with electron microscopes. The reason why geometry has led the way in this inquiry is due to the fact that where there is geometry there is utter simplicity coupled to rigorous order that underlies the phenomenon where it is recognized. Order allows variation but imposes at the same time a canalization that is patent in what we call evolution.



The Geometry Of Population Genetics


The Geometry Of Population Genetics
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Author : Ethan Akin
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-09

The Geometry Of Population Genetics written by Ethan Akin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-09 with Mathematics categories.


The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono graph I hope to show that his ideas illuminate many aspects of pop ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele model of selection plus recombination even when the fitness numbers are constant (i.e. no frequency dependence). This work is addressed to two different kinds of readers which accounts for its mode of organization. For the biologist, Chapter I contains a description of the entire work with brief indications of a proof for the harder results. I imagine a reader with some familiarity with linear algebra and systems of differential equations. Ideal background is Hirsch and Smale's text [15].



Genetic Diversity In Establishing Plant Populations


Genetic Diversity In Establishing Plant Populations
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Author : Steven H. Rogstad
language : en
Publisher: CRC Press
Release Date : 2011-09-02

Genetic Diversity In Establishing Plant Populations written by Steven H. Rogstad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Nature categories.


The new research described in this book demonstrates that the interplay of a host of founding conditions can frequently produce profound differences in population expansion rates and maintenance of genetic diversity in contrasting populations that differ, often only to slight degrees, in initial founding conditions. The goals of this book are twofo



Geometry From The Genetic Point Of View


Geometry From The Genetic Point Of View
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Author : Leroy Walter Sackett
language : en
Publisher:
Release Date : 1908

Geometry From The Genetic Point Of View written by Leroy Walter Sackett and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1908 with categories.




The Geometry Of Evolution


The Geometry Of Evolution
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Author : George R. McGhee
language : en
Publisher: Cambridge University Press
Release Date : 2006-12-07

The Geometry Of Evolution written by George R. McGhee and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-07 with Science categories.


The metaphor of the adaptive landscape - that evolution via the process of natural selection can be visualized as a journey across adaptive hills and valleys, mountains and ravines - permeates both evolutionary biology and the philosophy of science. The focus of this 2006 book is to demonstrate to the reader that the adaptive landscape concept can be put into actual analytical practice through the usage of theoretical morphospaces - geometric spaces of both existent and non-existent biological form - and to demonstrate the power of the adaptive landscape concept in understanding the process of evolution. The adaptive landscape concept further allows us to take a spatial approach to the concepts of natural selection, evolutionary constraint and evolutionary development. For that reason, this book relies heavily on spatial graphics to convey the concepts developed within these pages, and less so on formal mathematics.



Algebraic Biology Matrix Genetics And Genetic Intelligence


Algebraic Biology Matrix Genetics And Genetic Intelligence
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Author : Sergei V Petoukhov
language : en
Publisher: World Scientific
Release Date : 2023-08-02

Algebraic Biology Matrix Genetics And Genetic Intelligence written by Sergei V Petoukhov and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-02 with Science categories.


Historically, mathematics, probability, and statistics have been widely used in the biological sciences. Recent progress in genomics has yielded many millions of gene sequences. But what do these sequences tell us and what are the generalities and rules governed by them? It seems that we understand very little about the genetic contexts required to 'read' them. There is more to life than the genomic blueprint of each organism. Life functions within the natural laws that we know and the ones we do not know. The development of modern mathematical natural sciences is based on the use of certain mathematical tools. Mathematics can be used to understand life from the molecular to the biosphere level.This book provides the foundation and latest advances for an emerging research area that uses tools from symbolic computation, computer algebra and logic, algebraic geometry, fractal geometry, probability and statistics, and matrix algebra to formalize and solve biological problems and explore its applications in algebraic biology and code biology. It introduces highly interdisciplinary topics in biomathematics such as matrix genetics, gestalt biology, bio-antenna arrays, resonance genetics, quantum biology, and more.



Sacred Geometry


Sacred Geometry
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Author : Stephen Skinner
language : en
Publisher: Sterling Publishing Company, Inc.
Release Date : 2009

Sacred Geometry written by Stephen Skinner and has been published by Sterling Publishing Company, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Mathematics categories.


A fascinating and inspirational look at the vital link between the hidden geometrical order of the universe, geometry in nature, and the geometry of the man-made world. The Da Vinci Code has awakened the public to the powerful and very ancient idea that religious truths and mathematical principles are intimately intertwined. Sacred Geometry offers an accessible way of understanding how that connection is revealed in nature and the arts. Over the centuries, temple builders have relied on magic numbers to shape sacred spaces, astronomers have used geometry to calculate holy seasons, and philosophers have observed the harmony of the universe in the numerical properties of music. By showing how the discoveries of mathematics are manifested over and over again in biology and physics, and how they have inspired the greatest works of art, this illuminating study reveals the universal principles that link us to the infinite.