The Human Microbiome And Cancer
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The Human Microbiome And Cancer
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Author : Gary Moran
language : en
Publisher: Frontiers Media SA
Release Date : 2020-09-03
The Human Microbiome And Cancer written by Gary Moran and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-03 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Microbiome And Cancer
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Author : Erle S. Robertson
language : en
Publisher: Springer
Release Date : 2019-02-20
Microbiome And Cancer written by Erle S. Robertson and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-20 with Medical categories.
This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.
Human Microbiome In Health And Disease Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2022-09-23
Human Microbiome In Health And Disease Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-23 with Science categories.
Human Microbiome in Health and Disease, Volume 191, Part A presents updated knowledge on human microbiome as covered by renowned science faculty across the globe. Chapters in this volume include an introduction to human microbiome, Structure, functions and diversity of healthy human microbiome, Role of human microbiome in cancer, Gut microbiota and gastrointestinal cancer, Dysbiosis of human microbiome and metabolic diseases, Gut microbiome and type 2 diabetes, Gut microbiome and non-alcoholic fatty liver disease, Hepatic drug metabolism and intestinal microbiota, Emerging tools for understanding the human microbiome, and Microbiome therapeutics: Opportunity and challenges, and more. These chapters cover the composition, diversity, dynamics and functions of human microbiome in health and disease. This book will form an excellent and informative text on keystone, autochthonous, and exogenous microbiota important for human health in a simple to understand and easy to read format. Covers the structure, functions and diversity of human microbiome in health and disease Includes discussions on drug metabolisms and microbiome based therapeutics Presents emerging tools for understanding the human microbiome
The Human Microbiome An Issue Of Clinics In Laboratory Medicine
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Author : Matthew R. Pincus
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-11-12
The Human Microbiome An Issue Of Clinics In Laboratory Medicine written by Matthew R. Pincus and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-12 with Medical categories.
The Human Biome is a complex and essential biological system within the human body. The adult human harbors some 100 trillion bacteria in his gut alone. Balance of this system is essential to good health. This issue of Clinics in Laboratory Medicine focuses on treatments to realign this balance as well as advances in understanding the system in general. Topics include: Changes in microbiome in GERD; The relationship of microbiome, inflammation, and colon cancer; Gut microbiome and host genetics in Crohn's disease; Association of oral microbiome with head and neck cancer; The vaginal microbiome-disease, genetics and the environment;, The human virome in children and its relationship to febrile illness; Gut microbiome in irritable bowel syndrome; The neonatal microbiome and necrotizing enterocolitis; Fecal microbiota transplantation for clostridium difficile Infection.
The Human Microbiota And Microbiome
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Author : Julian R Marchesi
language : en
Publisher: CABI
Release Date : 2014-05-14
The Human Microbiota And Microbiome written by Julian R Marchesi and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-14 with Medical categories.
Thousands of different microbial species colonize the human body, and are essential for our survival. This book presents a review of the current understanding of human microbiomes, the functions that they bring to the host, how we can model them, their role in health and disease and the methods used to explore them. Current research into areas such as the long-term effect of antibiotics makes this a subject of considerable interest. This title is essential reading for researchers and students of microbiology.
The Human Microbiome Handbook
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Author : Jason Tetro
language : en
Publisher: DEStech Publications, Inc
Release Date : 2016-03-15
The Human Microbiome Handbook written by Jason Tetro and has been published by DEStech Publications, Inc this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-15 with Medical categories.
Critical reference explains strategies of microbiome research in humansSummarizes the microbiome's effects on immunity, metabolism, genetics and psychologyEvaluates medical and nutritional therapies for modifying the microbiomeFor healthcare researchers, nutritionists, microbiologists, and medical professionals Written by a team of leading scientists, this book offers a concise technical reference covering human microbiome research and its ramifications for medicine and nutrition. The initial chapters furnish a scientific explanation of the microbiome in general and its ecology. The book then provides a detailed investigation of microbial populations as these pertain to physiology, metabolism and immunology. The final portions are devoted to exploration of the microbiome's effects on chronic and autoimmune diseases and include assessments of clinical therapies and nutritional interventions designed to alter the microbiome to mitigate chronic health conditions.
The Human Microbiota And Chronic Disease
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Author : Luigi Nibali
language : en
Publisher: John Wiley & Sons
Release Date : 2016-10-03
The Human Microbiota And Chronic Disease written by Luigi Nibali and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-03 with Science categories.
Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.
Human Microbiome
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Author : Sabu Thomas
language : en
Publisher: Springer Nature
Release Date : 2022-02-02
Human Microbiome written by Sabu Thomas and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-02 with Medical categories.
The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. This book talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.
Inflammation Infection And Microbiome In Cancers
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Author : Jun Sun
language : en
Publisher: Springer Nature
Release Date : 2021-04-20
Inflammation Infection And Microbiome In Cancers written by Jun Sun and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-20 with Medical categories.
This book offers a summary and discussion of the advances of inflammation and infection in various cancers. The authors cover the classically known virus infections in cancer, novel roles of other pathogens (e.g. bacteria and fungi), as well as biomarkers for diagnosis and therapy. Further, the chapters highlight the progress of immune therapy, stem cells and the role of the microbiome in the pathophysiology of cancers. Readers will gain insights into complex microbial communities, that inhabit most external human surfaces and play a key role in health and disease. Perturbations of host-microbe interactions often lead to altered host responses that can promote cancer development. Thus, this book highlights emerging roles of the microbiome in pathogenesis of cancers and outcome of therapy. The focus is on mechanistic concepts that underlie the complex relationships between host and microbes. Approaches that can inhibit infection, suppress chronic inflammation and reverse the dysbiosis are discussed, as a means for restoring the balance between host and microbes. This comprehensive work will be beneficial to researchers and students interested in infectious diseases, microbiome, and cancer as well as clinicians and general physiologists.
The Human Microbiome Diet And Health
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Author : Food Forum
language : en
Publisher: National Academies Press
Release Date : 2013-02-27
The Human Microbiome Diet And Health written by Food Forum and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-27 with Medical categories.
The Food Forum convened a public workshop on February 22-23, 2012, to explore current and emerging knowledge of the human microbiome, its role in human health, its interaction with the diet, and the translation of new research findings into tools and products that improve the nutritional quality of the food supply. The Human Microbiome, Diet, and Health: Workshop Summary summarizes the presentations and discussions that took place during the workshop. Over the two day workshop, several themes covered included: The microbiome is integral to human physiology, health, and disease. The microbiome is arguably the most intimate connection that humans have with their external environment, mostly through diet. Given the emerging nature of research on the microbiome, some important methodology issues might still have to be resolved with respect to undersampling and a lack of causal and mechanistic studies. Dietary interventions intended to have an impact on host biology via their impact on the microbiome are being developed, and the market for these products is seeing tremendous success. However, the current regulatory framework poses challenges to industry interest and investment.