The Interconnection Between The Tumor Microenvironment And Immunotherapy In Brain Tumors
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The Interconnection Between The Tumor Microenvironment And Immunotherapy In Brain Tumors
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Author : Quan Cheng
language : en
Publisher: Frontiers Media SA
Release Date : 2023-06-08
The Interconnection Between The Tumor Microenvironment And Immunotherapy In Brain Tumors written by Quan Cheng and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-08 with Medical categories.
Cancer Immunology And Immunotherapy
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Author : Mansoor M. Amiji
language : en
Publisher: Elsevier
Release Date : 2021-08-27
Cancer Immunology And Immunotherapy written by Mansoor M. Amiji and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-27 with Business & Economics categories.
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. Comprehensive treaty covering all aspects of immuno-oncology (IO) Novel strategies for delivery of IO therapeutics and vaccines Forecasting on the future of nanotechnology and drug delivery for IO
Ionizing Radiation And The Immune Response Part B
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-07-10
Ionizing Radiation And The Immune Response Part B written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-10 with Science categories.
Ionizing Radiation and the Immune Response, Part B, Volume 378 reviews the latest knowledge on the immune response induced by ionizing radiations. Specific chapters in this new release include NK functions in radio-induced immune response, TRT and immune response, Radio-induced immune response and lipid metabolism, Effect of protons and heavy ions on immune response, Effect of flash therapy and mini beam on immune response, Radio-induced lymphopenia, CT to potentiate radio-induced immune response, Impact of RT on healthy tissues (inflammation), Radio-induced macrophagic response, To use nanoparticles and ionizing radiations to modulate immune response: opinion of the chemist, biologist and clinician, and much more. Other sections cover the Role of Dendritic cells in radiation-induced immune response, the Relationship between the tumor microenvironment and the efficacy of the radiotherapy/immunotherapy combination, and Biomarkers of radiation induced response to optimize radio-immunotherapy combination. - Covers the latest insights about the biological parameters modulating radio-induced immune response - Provides an accurate review by selected experts of the impact on the immune response of radio-enhancer nanoparticles or chemotherapy targeting immunosuppressive immune cells - Presents valuable information to clinicians to optimize radiotherapy and immunotherapy combinations
The Immunology And Biology Of Brain Tumors
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Author : Michael Graner
language : en
Publisher: MDPI
Release Date : 2021-05-04
The Immunology And Biology Of Brain Tumors written by Michael Graner and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-04 with Medical categories.
Immunotherapy has become a viable treatment modality for a variety of cancers (and referred to as Science Magazine’s “Breakthrough of the Year” in 2013, as well as ASCO’s “Advance of the Year” in both 2016 and 2017). This Special Issue is focused on the relevance of immunobiology in brain tumors, touching on elements of immune suppression, immune stimulation, and the immune microenvironment, with culminations in translational immunotherapy.
Clinical Therapy Of Brain Tumors
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Author : Bo yuan Huang
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-09
Clinical Therapy Of Brain Tumors written by Bo yuan Huang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-09 with Medical categories.
Brain tumors are devastating diseases, accounting for a significant proportion of cancer-related mortality and morbidity in both adults and children. Over the past few years, we have witnessed dramatic progress in clinical treatment for brain tumors. This is largely due to advancements in surgical skills, a more reasonable and personalized approach to radiotherapy and chemotherapy, and continuously updated immune therapy methods that modulate the immune microenvironment or specifically target tumor cells. However, various factors affect brain tumor treatments. These include the blood-brain barrier, tumor heterogeneity, the tumor immune microenvironment, and so on. Consequently, it is worthwhile that research conducted in these fields, both pre- and clinical, should be shared with the larger scientific community to further improve the clinical treatment for brain tumors. The Research Topic’s ambitions are to bring together new discoveries in the clinical treatment for brain tumors. Manuscripts consisting of surgical approaches, radiotherapy, chemotherapy, immunotherapy, and other therapies on brain tumors are welcomed. Manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases that are not accompanied by validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this Topic section. We welcome manuscripts in the form of Original Research and Review focusing on, but not limited to, the following sub-topic: 1) The advancements in surgical techniques, including updated operative routes, minimally invasive approaches, and image-guided navigation systems. 2) In vitro, ex vivo, and in vivo tumor-related models analyzing the tumor and immune microenvironment and response to targeted brain tumor therapies. 3) Fundamental experimental studies, pre-clinical, and clinical research on novel strategies of chemotherapy, radiotherapy, and/or immunotherapy.
Advanced Concepts And Strategies In Central Nervous System Tumors
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Author :
language : en
Publisher: BoD – Books on Demand
Release Date : 2025-04-30
Advanced Concepts And Strategies In Central Nervous System Tumors written by and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-30 with Medical categories.
This book features innovative diagnostic and therapeutic strategies for central nervous system tumors, which remain among the deadliest cancers. It is meant to serve as a comprehensive expert review of cutting-edge topics for researchers and clinicians to understand evolving concepts and approaches. Featured topics include computational applications in pathology, state-of-the-art classification tools, novel technology-based treatments, applications of stem cells, current perspectives in immunotherapy, innovative targeted therapies, advanced drug delivery, and special considerations for pediatric tumors.
The Roles Of Immune Cell Homeostasis In Cancer Research And Therapeutic Response
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Author : Zhijie Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-07-03
The Roles Of Immune Cell Homeostasis In Cancer Research And Therapeutic Response written by Zhijie Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-03 with Science categories.
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis 2nd Edition
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Author : Zhouxiao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-25
The Role Of The Tumor Microenvironment Tme And Relevant Novel Biomarkers In Oncogenesis 2nd Edition written by Zhouxiao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-25 with Science categories.
Tumors and their surroundings are closely related and constantly interact. Tumors can influence their microenvironment by releasing cell signaling molecules that promote neoplasm angiogenesis and induce immune tolerance, while immune cells in the microenvironment can influence cancer cell growth and development. The tumor microenvironment (TME), a complex biological ecosystem for cancer cells to survive and develop refers to the surrounding circumstances of cancer cells, including surrounding blood vessels, immune cells, fibroblasts, bone marrow inflammatory cells, various signaling molecules and extracellular matrix (ECM). The immune cells and their regulation mode in TME have tumor-antagonizing or tumor-promoting functions. TME has been gradually recognized as a key contributor to cancer progression and drug resistance, with cellular components in the TME able to enhance tumor resistance by recruiting and secreting multiple protective cytokines. The acellular components of TME can mediate drug resistance by building physical barriers, affecting tumor cell growth and metabolism, etc. Knowledge of the above is paving the way for identifying new targets and discovering new therapies. Studying the dynamic relationship between tumor surroundings and neoplasm, and clarifying the molecular mechanism of different factors refers to TME in the process of tumor progression, are the key elements of cancer inhibition. Currently, there is a proliferation of publicly available tumor genomic databases. Such as the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), Surveillance, Epidemiology, and EndResults Program (SEER), International Cancer Genome Consortium (ICGC) and National Cancer Database (NCDB). These abundant public database resources enable researchers to mine multi-omics cancer data to better understand the interactions between tumors and their microenvironment and to discover biomarkers and therapeutic targets in TME that are associated with tumorigenesis. This provides new targets for early diagnosis and precise treatment of tumors. In this research topic, we would like to demonstrate the function and mechanism of tumor microenvironment in tumorigenesis and development through various methods, including sequencing, bioassay, experimental models such as PDX and organoids. We welcome original research articles and reviews dedicated to: 1) Mechanisms of tumor microenvironment involvement in tumor progression. 2) Bioinformatics or big data demonstrating the role of the tumor microenvironment in tumor progression 3) Molecular therapeutic mechanisms and clinical studies related to the tumor microenvironment 4) Biomarkers and therapeutic targets related to tumor microenvironment 5) Drug resistance mechanism related to tumor microenvironment
Insights In Cancer Immunity And Immunotherapy 2022
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Author : Katy Rezvani
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-17
Insights In Cancer Immunity And Immunotherapy 2022 written by Katy Rezvani and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-17 with Medical categories.
Transcriptional Regulation In Metabolism And Immunology
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Author : Chunjie Jiang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-03
Transcriptional Regulation In Metabolism And Immunology written by Chunjie Jiang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-03 with Science categories.