The Lectins
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The Lectins
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Author : Irvin Liener
language : en
Publisher: Elsevier
Release Date : 2012-12-02
The Lectins written by Irvin Liener and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
The Lectins: Properties, Functions, and Applications in Biology and Medicine is a 10-chapter text that deals with the advances in research studies on the properties, functions, and applications of lectins in biology and medicine. The first two chapters consider the historical development, physicochemical properties, isolation, and remarkable specificity toward sugars of lectins. These topics are followed by a discussion on the molecular aspects of protein evolution, with a particular emphasis on lectins, which provide an excellent example of a family of homologous proteins. The following chapters explore the diverse biological activities of lectins and how these properties are utilized for the isolation and characterization of carbohydrate-containing compounds in solution and on cells. A chapter focuses on the functions of lectins in their natural milieu. This text further covers the importance of lectins in nonplant systems as exemplified by lectins that occur in vertebrates, slime molds, and bacteria. The last chapter highlights the nutritional significance of the occurrence of lectins in plant foods such as legumes. This book is an ideal source for organic chemists, protein researchers, and workers in the fields of biology and medicine.
Lectins
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Author : Nathan Sharon
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lectins written by Nathan Sharon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
A characteristic property of most, or perhaps all, proteins is their ability to combine specifically and reversibly with various substances. Well known examples are enzymes that bind substrates and inhibitors, and antibodies that bind antigens. This book deals with lectins, a class of proteins that bind carbohydrates. Another characteristic property of lectins is that they agglutinate cells or precipitate polysaccharides and glycoproteins. This is because lectins are polyvalent, i.e. each lectin molecule has at least two carbohydrate binding sites to allow crosslinking between cells (by combining with sugars on their surfaces) or between sugar containing macromolecules. The agglutinating and precipitating activities of lectins are very similar to those of antibodies. They can likewise be specifically inhibited by low molecular weight compounds (haptens), which in the case of lectins are sugars or sugar containing compounds (Fig. 1.1). Not surprisingly, therefore, many of the methods used in lectin research are based on immunochemical techniques. Nevertheless, lectins are different from antibodies in several important aspects. Many lectins are found in plants, microorganisms and viruses, which do not synthesize immunoglobulins. In fact, they are found in almost all living organisms (Table 1.1) and are not confined to specific organs or tissues. Another marked difference between the two classes of compound is that antibodies are structurally similar, whereas lectins are structurally diverse. In general, lectins are oligomeric proteins composed of subunits, usually with one sugar binding site per subunit.
Lectins
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Author : Nathan Sharon
language : en
Publisher: Springer Science & Business Media
Release Date : 2003-12-31
Lectins written by Nathan Sharon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-31 with Medical categories.
This Second Edition brings readers up to date with all the latest findings in lectin research. Throughout this new edition, more than 200 figures and some thirty tables help readers visualize and understand key concepts and processes. The book starts with an overview of lectin research followed by a survey of the occurrence of lectins in nature. Other areas covered include the nutritional effects of lectins and their functions in nature.
Lectins Analytical Technologies
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Author : Carol L. Nilsson
language : en
Publisher: Elsevier
Release Date : 2011-10-13
Lectins Analytical Technologies written by Carol L. Nilsson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-13 with Science categories.
Lectins: Analytical Technologies covers both analytical and biological aspects of lectins (functional carbohydrate (complex sugar) recognition proteins) and provides researchers in the field with a resource containing background information and 'look-up' tables detailing lectin specificity and structures. Also included are methods and practical tips for designing new lectins from existing non-lectin proteins, automated approaches to lectin proteomics and high resolution mass spectrometry techniques. This book will be of interest to both novice and advanced researchers in biomedical, analytical and pharmaceutical fields who are involved in the study of lectin structures or who utilize lectins as analytical tools. The study of lectins and their employment in analytical settings spans a range of fields including: * Crystallography and lectin structure databases * Carbohydrate microarrays for lectin characterization and glycotope identification * Proteomic approaches to the functional identification of bacterial adhesins * Generation of lectins from enzymes * Probing cell-surface lectins with neoglycoconjugates * Reviews up-to-date techniques, including practical hints for laboratory work * Provides overview of lectin e-resources and several color illustrations * Includes a 'look-up' table detailing lectin specificity
Lectins
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Author : Nathan Sharon
language : en
Publisher: Springer
Release Date : 2011-09-29
Lectins written by Nathan Sharon and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-29 with Science categories.
A characteristic property of most, or perhaps all, proteins is their ability to combine specifically and reversibly with various substances. Well known examples are enzymes that bind substrates and inhibitors, and antibodies that bind antigens. This book deals with lectins, a class of proteins that bind carbohydrates. Another characteristic property of lectins is that they agglutinate cells or precipitate polysaccharides and glycoproteins. This is because lectins are polyvalent, i.e. each lectin molecule has at least two carbohydrate binding sites to allow crosslinking between cells (by combining with sugars on their surfaces) or between sugar containing macromolecules. The agglutinating and precipitating activities of lectins are very similar to those of antibodies. They can likewise be specifically inhibited by low molecular weight compounds (haptens), which in the case of lectins are sugars or sugar containing compounds (Fig. 1.1). Not surprisingly, therefore, many of the methods used in lectin research are based on immunochemical techniques. Nevertheless, lectins are different from antibodies in several important aspects. Many lectins are found in plants, microorganisms and viruses, which do not synthesize immunoglobulins. In fact, they are found in almost all living organisms (Table 1.1) and are not confined to specific organs or tissues. Another marked difference between the two classes of compound is that antibodies are structurally similar, whereas lectins are structurally diverse. In general, lectins are oligomeric proteins composed of subunits, usually with one sugar binding site per subunit.
The Lectins
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Author : Irvin L. Liener
language : en
Publisher:
Release Date : 1986
The Lectins written by Irvin L. Liener and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Handbook Of Plant Lectins
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Author : Els. J. M. Van Damme
language : en
Publisher: John Wiley & Sons
Release Date : 1998-03-06
Handbook Of Plant Lectins written by Els. J. M. Van Damme and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-03-06 with Science categories.
Plant lectins are extensively used as tools and as bioactiveproteins in different areas of biomedical and biological research.The Handbook of Plant Lectins provides a comprehensive yet conciseoverview of the biochemical properties, carbohydrate-bindingspecificity, biological activities and applications of most of thecurrently known plant lectins. This handbook consists of two majorsections: an introductory guide and a quick reference dictionary.Part I acquaints the newcomer to the lectin field with theessential information on lectins and their importance tobiomedicine: * what are lectins? * their carbohydrate-binding specificity * effects on nutrition and immunology * use in histochemistry * application as therapeutic agents Part II lists approximately 200 lectin entries in alphabeticalorder. Each entry deals with the lectin(s) of a particular plantand provides, (where known), details of: * isolation and characterisation; * sugar binding specificity; * biological activities; * applications; * commercial availability; and, * a bibliography. Useful summary tables list lectins according to their specificity,thereby allowing the user to choose the best lectin for theirapplication. A list of suppliers is also provided. Handbook ofPlant Lectins will be of interest to biologists and biomedicalresearchers studying cell biology, cancer research, nutrition,immunology, pathology and physiology.
Lectins
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Author : Nathan Sharon
language : en
Publisher:
Release Date : 1996
Lectins written by Nathan Sharon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with categories.
Lectins And Glycobiology
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Author : Hans-Joachim Gabius
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lectins And Glycobiology written by Hans-Joachim Gabius and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The intriguing complexity, precision, and regulation of the wide range of biologi cal processes is determined by intricate mechanisms of molecular recognition. Their nature is under intense scrutiny. In addition to the well-appreciated interac tion of proteins either with amino acid or nucleotide sequences, the investigation of their interplay with carbohydrate elements of cellular glycoconjugates current ly exerts increasing attraction. In the group of carbohydrate-binding proteins, lec tins are distinguished from antibodies or ligand-affecting enzymes, according to the most recent definition. The thorough analysis of their structure and function is considered as a focus to collect a critical mass of information for delineating details of a further array of biochemical processes with pivotal physiological im pact. Following an already century-long history of scientific description, reflected by subjectively chosen highlights (see the Brief History of Lectin Research at page VI), the excitement in glycobiological research that prevails today can easily be ex plained by our growing awareness of the multifarious significance of a sugar-code system of biological information. This present notion unmistakably has an im pact on lines of research in diverse disciplines like cell and molecular biology, histochemistry, or clinical sciences. It also prompts inherent practical questions such as how to obtain lectins, or how to employ them as instruments in various assay systems with the best possible results. Thus, this book is devoted intentionally to cover the techniques in different research fields that deal with lectins.
Lectin Free Handbook
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Author : Stanley Adamson
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2018-06-19
Lectin Free Handbook written by Stanley Adamson and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-19 with categories.
The lectin free diet is recommended for those who suffer from inflammatory or autoimmune conditions. If you have not found relief by eliminating FODMAPS or gluten from your diet, getting rid of lectins may do you a lot of good. Researchers have identified lectins to be a considerable source of food sensitivity and digestive problems. Amongst other problems, they are anti-nutrient in nature, cause inflammation, autoimmune diseases as well as weight gain. This book takes a balanced look at how lecins affect our bodies and provides a simple, straightforward guide to starting the lectin-free diet. In the Lectin Free Handbook, you will find: Negative Effects Of Lectins On The Human Body Positive Effects Of Lectins And Lectin Containing Foods Signs Of Lectin Exposure The Most Harmful Lectin Foods To Avoid How To Reduce The Lectin Amount In High-Lectin Foods Allowed And Excluded Foods A 7 Days Meal Plan With 21 Lectin Free Recipes With the information in this book, you can stay lectin free and also eat a rich and healthy diet that has all the necessary vitamins, minerals and antioxidants.