[PDF] The Leukotrienes - eBooks Review

The Leukotrienes


The Leukotrienes
DOWNLOAD

Download The Leukotrienes PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get The Leukotrienes book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page



The Leukotrienes


The Leukotrienes
DOWNLOAD
Author : Lawrence Chakrin
language : en
Publisher: Elsevier
Release Date : 2012-12-02

The Leukotrienes written by Lawrence Chakrin and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Nature categories.


The Leukotrienes, Chemistry and Biology discusses the significant scientific progress of leukotrienes, from the discovery of slow-reacting substance to the chemical identification of a mixture of leukotrienes. Composed of 11 chapters, the book presents an enormous increase in research on the chemistry and biology of these and related substances, especially as they relate to the etiology of allergic and inflammatory diseases. After briefly discussing the continuing perspectives on the leukotriene biology, the book describes the structure, synthesis, formation, and biological actions of leukotrienes. This is followed by a discussion on arachidonic metabolism for the development of therapeutic agents specifically designed to either inhibit the synthesis or antagonize the effects of the leukotrienes. The book also looks into the biochemical and pharmacologic control of the synthesis and actions of leukotrienes. The information is considered in the context of the specific enzymes in the pathway that may be affected by any given agent. The in vivo studies on the pulmonary mechanical effect of leukotrienes, the pharmacologic activity of leukotriene receptors, and the antagonistic property of peptidoleukotrienes as an approach to allergic disease treatment are considered in the concluding chapters of the book. This book will be of value to scientists and researchers interested in hypersensitivity reactions, inflammation, and allergic diseases.



The Leukotrienes


The Leukotrienes
DOWNLOAD
Author : Priscilla J. Piper
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 1986

The Leukotrienes written by Priscilla J. Piper and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical categories.




Leukotrienes


Leukotrienes
DOWNLOAD
Author : Ian Rodger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Leukotrienes written by Ian Rodger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


In the two decades since the elusive "slow reacting substance of anaphylaxis" (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the leukotrienes are key mediators of both alIergy and inflammation. Their release by alIergen or other challenge has been demonstrated in the lungs of asthmatic subjects, and measurement of urinary leukotriene concentrations in such patients has been shown to be a valuable, non invasive indicator. Significant progress has been made towards the characterization of the leukotriene receptor subtypes, exemplified by the cloning of the LTB4 receptor earlier this year. Coupled with this there has been a continued elucidation of signal transduction mechanisms underlying receptor activation. Consequent upon these advances has been the development of potent antagonists of the CysLT receptor, J and both these and inhibitors of leukotriene biosynthesis have entered clinical practice in the therapy of asthma. In this clinical setting antagonists of the CysLTJ receptor have been shown to be an effective therapy in chronic asthmatics, against antigen- and exercise-induced bronchoconstriction, and in aspirin-intolerant asthmatics. The advent of this new class of agents promises to change the way in which asthmatic patients are currently treated.



Biology Of The Leukotrienes


Biology Of The Leukotrienes
DOWNLOAD
Author : Roberto Levi
language : en
Publisher:
Release Date : 1988

Biology Of The Leukotrienes written by Roberto Levi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.




Leukotrienes And Lipoxygenases


Leukotrienes And Lipoxygenases
DOWNLOAD
Author : Joshua Rokach
language : en
Publisher: Elsevier Publishing Company
Release Date : 1989

Leukotrienes And Lipoxygenases written by Joshua Rokach and has been published by Elsevier Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Health & Fitness categories.


Important advances have been made in the chemistry and biochemistry of the leukotrienes mainly as a result of the development of new biophysical and biochemical methodologies. The extraordinary effort of many scientists and the interactions of many scientific disciplines has created a vast amount of data and information and, with it, the need for a book addressing all aspects of this multidisciplinary field. This book has been written to respond to that need. It comprises six chapters which together provide a cohesive interdisciplinary coverage of the field, from the organic, analytical aspect to the biological sciences. Among the many subjects covered are many aspects of the leukotriene field which have not been covered in detail before, i.e. the numerous methodologies employed in the detection, localization and quantitation of lipoxygenase products; the role of leukotrienes in human disease states; leukotriene antagonists and lipoxygenase inhibitors, and potential therapeutic agents. The book brings together a wide variety of material to give a valuable overview of this important subject.



The Leukotrienes


The Leukotrienes
DOWNLOAD
Author : Michael Klaus Bach
language : en
Publisher:
Release Date : 1983

The Leukotrienes written by Michael Klaus Bach and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.




Leukotrienes


Leukotrienes
DOWNLOAD
Author : Ian Rodger
language : en
Publisher: Springer
Release Date : 1998-02-28

Leukotrienes written by Ian Rodger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-02-28 with Medical categories.


In the two decades since the elusive "slow reacting substance of anaphylaxis" (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the leukotrienes are key mediators of both alIergy and inflammation. Their release by alIergen or other challenge has been demonstrated in the lungs of asthmatic subjects, and measurement of urinary leukotriene concentrations in such patients has been shown to be a valuable, non invasive indicator. Significant progress has been made towards the characterization of the leukotriene receptor subtypes, exemplified by the cloning of the LTB4 receptor earlier this year. Coupled with this there has been a continued elucidation of signal transduction mechanisms underlying receptor activation. Consequent upon these advances has been the development of potent antagonists of the CysLT receptor, J and both these and inhibitors of leukotriene biosynthesis have entered clinical practice in the therapy of asthma. In this clinical setting antagonists of the CysLTJ receptor have been shown to be an effective therapy in chronic asthmatics, against antigen- and exercise-induced bronchoconstriction, and in aspirin-intolerant asthmatics. The advent of this new class of agents promises to change the way in which asthmatic patients are currently treated.



The Pulmonary Effects Of The Leukotrienes


The Pulmonary Effects Of The Leukotrienes
DOWNLOAD
Author : Robert H. Gundel
language : en
Publisher:
Release Date : 1983

The Pulmonary Effects Of The Leukotrienes written by Robert H. Gundel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.




The Leukotrienes


The Leukotrienes
DOWNLOAD
Author : Frederik Jan Zijlstra
language : en
Publisher:
Release Date : 1988

The Leukotrienes written by Frederik Jan Zijlstra and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with categories.




Novel Inhibitors Of Leukotrienes


Novel Inhibitors Of Leukotrienes
DOWNLOAD
Author : Giancarlo Folco
language : en
Publisher: Springer
Release Date : 2012-12-06

Novel Inhibitors Of Leukotrienes written by Giancarlo Folco and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Many new antileukotriene drugs are now marketed as antiasthma drugs and represent the first new drugs in this field since the 1970s. This book covers the steps that have led to the discovery and development of these new drugs and offers detailed descriptions of their clinical applications. The review chapters on the main aspects of basic and applied leukotriene research are written by leading specialists in the field, and the volume takes a new approach in presenting information of particular interest to both scientists and clinicians in the fields of asthma, inflammation and allergic diseases.