The Melanin Effect
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The Melanin Effect
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Author : Jo Dash
language : en
Publisher:
Release Date : 2020-05-15
The Melanin Effect written by Jo Dash and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-05-15 with categories.
The Melanin Effect book offers readers the best work from some of the world's leading researchers, scholars and scientists on melanin. Understanding melanin can offer you an insight to the universal truth that we are all unique and that's what makes us special in every way. Opening up your understanding of melanin to your own optimal diet, mental state, emotional well-being and greater consciousness. Our ancestors spoke about the third eye and the body being a temple for resurrection by light. Modern science and ancient science have never had such a fruitful discussion than this book. It's for the curious, the willing, the thought provoking, the self developer, the self identity proclaimer and the enlightened ones who are known as the "Melanin Effect".
The Melanin Effect 2
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Author : Joseph “Jo Dash” Musa
language : en
Publisher: AuthorHouse
Release Date : 2023-09-29
The Melanin Effect 2 written by Joseph “Jo Dash” Musa and has been published by AuthorHouse this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with Body, Mind & Spirit categories.
"The Melanin Effect 2 - A Nutritional Path Back To Eden" is an enlightening and comprehensive nutritional book that delves into the intriguing intersection between food, culture, and its profound biological impact on our existence. By exploring the historical, cultural, and scientific dimensions of food, this book offers readers a deeper understanding of the intricate relationship between what we eat and who we are. Drawing from a rich tapestry of research and anecdotes, "The Melanin Effect 2 - A Nutritional Path Back To Eden" embarks on a captivating journey through time, exploring the origins and evolution of various culinary traditions and their significance in shaping human civilisation. From ancient civilisation to modern societies, the book uncovers the cultural practices, rituals, and beliefs surrounding food that have endured across generations.
The Melanin Effect 2
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Author : Joseph Jo Dash Musa
language : en
Publisher: Authorhouse UK
Release Date : 2023-09-29
The Melanin Effect 2 written by Joseph Jo Dash Musa and has been published by Authorhouse UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-29 with categories.
"The Melanin Effect 2 - A Nutritional Path Back To Eden" is an enlightening and comprehensive nutritional book that delves into the intriguing intersection between food, culture, and its profound biological impact on our existence. By exploring the historical, cultural, and scientific dimensions of food, this book offers readers a deeper understanding of the intricate relationship between what we eat and who we are. Drawing from a rich tapestry of research and anecdotes, "The Melanin Effect 2 - A Nutritional Path Back To Eden" embarks on a captivating journey through time, exploring the origins and evolution of various culinary traditions and their significance in shaping human civilisation. From ancient civilisation to modern societies, the book uncovers the cultural practices, rituals, and beliefs surrounding food that have endured across generations.
Melanin
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Author : Xiao-Peng Ma
language : en
Publisher: Nova Science Publishers
Release Date : 2012
Melanin written by Xiao-Peng Ma and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Human skin color categories.
Human melanin is synthesized in melanosomes located in melanocytes of the skin, hair, eyes, and leptomeninges. In this book, the authors present current research in the study of the biosynthesis, functions and health effects of melanin.
The Effect Of Melanin On Eye Color And Reaction Time
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Author : Deborah J. Carlson
language : en
Publisher:
Release Date : 1992
The Effect Of Melanin On Eye Color And Reaction Time written by Deborah J. Carlson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Color of eyes categories.
The Effect Of Melanin On Glycine And Dna
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Author : Michelle R. Ziegler
language : en
Publisher:
Release Date : 1991
The Effect Of Melanin On Glycine And Dna written by Michelle R. Ziegler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with DNA polymerases categories.
The Effect Of Extracellular Tyrosine On Melanin Synthesis
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Author : David Havey
language : en
Publisher:
Release Date : 1976
The Effect Of Extracellular Tyrosine On Melanin Synthesis written by David Havey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Melanins categories.
Naturally Occurring Melanin Synthesis Regulators And Their Modes Of Action
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Author : Hiroki Satooka
language : en
Publisher:
Release Date : 2011
Naturally Occurring Melanin Synthesis Regulators And Their Modes Of Action written by Hiroki Satooka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
The effect of various naturally occurring and structurally related chemical compounds on mushroom tyrosinase and B16-F10 melanoma cells were examined. For each natural product or related compound, the detailed mechanism of regulatory effect on tyrosinase-catalyzed melanin synthesis was elucidated, and occasionally, the optimal mechanism of cytotoxicity on B16 melanoma cells exhibited by chemical compounds are evaluated. Arbutin (hydroquinone-o-beta-D-glucopyranoside), a well-known depigmenting reagent, was oxidized by tyrosinase to the corresponding o-quinone with an extremely slow rate, and this reactive metabolite caused melanocytotoxicity, resulting in the antimelanogenic effect. Another monophenol derivative, thymol (5-methyl-2-isopropylphenol), on the other hand, did not act as either a substrate or an inhibitor, but it acted as a redox inhibitor, due to its prooxidative property, to disrupt the melanin formation. This prooxidant effect also triggered the prooxidative-related toxicity on melanoma cells. In the case of cardols (5-alkylresorcinol), naturally occurring resorcinolic lipid, hydrophilic head, and hydrophobic tail concept was applied to the mechanism of both tyrosinase inhibition and cytotoxicity. More specifically, resorcinol moiety quickly and reversibly bound to binuclear copper of tyrosinase, and then, hydrophobic tail portion slowly and irreversibly interacted with the hydrophobic portions proximate to the active site of the enzyme. However, this inhibitory mechanism was only observed when the hydrophobic alkyl chain was long enough to interact with the hydrophobic portion of the enzyme. In the case of cellular effect, cardol (C15:3) preferentially acted as a surfactant to disrupt the function of cellular membrane while cardol (C5:0) produced prooxidant-related toxicity. Alkyl-3,5-dihydroxybenzoate and 3,5-dihydroxyphenyl alkanoate with various lengths of alkyl chain were examined to clarify the effect of the lengths of alkyl chain on inhibitory and toxic effect. In the cases of both alkyl-3,5-dihydroxybenzoate and 3,5-dihydroxyphenyl alkanoate, basically, both compounds with alkyl chain longer than C9 caused a two-step inactivation on mushroom tyrosinase. In addition, alkyl-3,5-dihydroxybenzoate acted as a surfactant to cause cytotoxicity while 3,5-dihydroxyphenyl alkanoate were decomposed in the growth medium. Alkyl-3,5-dihydroxybenzoate, interestingly and importantly, inhibited melanogenesis without affecting any cell growth, which is due to the combined effect of the two-step tyrosinase inactivation and surfactant activity. Finally, the effect of polyphenolic compounds, resveratrol and luteolin, were subjects to elucidate their effect on tyrosinase and B16 melanoma cells. In both cases, tyrosinase oxidized them to the corresponding o-quinone. However, in the case of resveratrol (trans-3,5,4'-trihydroxystilbene), the corresponding o-quinone irreversibly interacted with tyrosinase, indicating that kcat type (suicide) inhibition was the mechanism of inhibition. Resveratrol did not show any toxicity up to 200 mu M, and at 200 mu M, melanogenesis was suppressed with the addition of resveratrol. Luteolin (2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone), on the other hand, the corresponding o-quinone did not inhibit tyrosinase but did act as a redox cycler, which oxidized leukodopachrome to dopachrome when luteolin was coexisted L-DOPA and tyrosinase. In the case of luteolin, luteolin o-quinone was also an active principle for the toxicity. Through the investigation, the biological significance of each molecule was observed. Based on the dynamic perspective and the biological significance, the possible utilization of these chemicals was also discussed.
The Protective Effect Of Melanin Against Radiation
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Author : George A. Swan
language : en
Publisher:
Release Date : 1976
The Protective Effect Of Melanin Against Radiation written by George A. Swan and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with categories.
Oxidation and reduction of autoxidative dopa-melanin were studied. Reduction with neither ascorbic acid nor sodium dithionite led to any overall increase in the number of 5,6-dihydroxyindole units in the melanin polymer. The melanin was oxidised using repsectivley potassium ferricyanide and ceric sulphate solutions but in neither case was the melanin e.s.r. signal diminished. The interaction of melanin's free radicals with cupric ions was shown not to be chemical in nature. The number of bound cupric ions was determined and the value used to calculate the number of free radicals in autoxidative dopa-melanin.
Melanins And Melanogenesis
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Author : Giuseppe Prota
language : en
Publisher: Academic Press
Release Date : 1992-10
Melanins And Melanogenesis written by Giuseppe Prota and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10 with Medical categories.
A book aimed at cell biologists, biochemists, research physicians and dermatologists as well as university and medical libraries. This book focuses on all aspects of melanin pigmentation, providing a concise, comprehensive picture of the new knowledge gained at the frontiers of research.