The Molecular Switch
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The Molecular Switch
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Author : Rob Phillips
language : en
Publisher: Princeton University Press
Release Date : 2020-08-18
The Molecular Switch written by Rob Phillips and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-18 with Science categories.
A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons. Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.
Molecular Switches
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Author : Ben L. Feringa
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-04
Molecular Switches written by Ben L. Feringa and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-04 with Science categories.
Täglich benutzen wir Schalter, um strombetriebene Geräte an- und abzuschalten und kein Compuer würde ohne sie funktionieren. Nach den gleichen Prinzipien funktionieren auch molekulare Schalter, die unter dem Einfluß ihrer Umwelt zwischen zwei definierten Zuständen wechseln können. Im Gegensatz zu den gewöhnlichen Schaltern sind molekulare Schalter aber außerordentlich klein und ihre Anwendung in der Nanotechnologie, Biomedizin und im Computerchipdesign öffnet neue Horizonte. Im vorliegenden Zweibänder berichten Herausgeber und Autoren über molekulare Schalter aus Katenanen und Rotaxanen, Fulgiden, Flüssigkristallen und Polypeptiden. Die Bandbreite der behandelten Themen reicht von chiroptischen Schaltern über multifunktionale Systeme bis hin zu molekularen logischen Schaltungen. Chemiker und Materialwissenschaftler in Industrie und Hochschule, die sich für einen der innovativsten Bereiche ihrer Wissenschaft interessieren, werden dieses Buch mit Gewinn lesen!
The Molecular Switch
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Author : Rob Phillips
language : en
Publisher: Princeton University Press
Release Date : 2020-09
The Molecular Switch written by Rob Phillips and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09 with Science categories.
A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons. Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.
Chiroptical Molecular Switches
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Author : Anne Marie Schoevaars
language : en
Publisher:
Release Date : 1998
Chiroptical Molecular Switches written by Anne Marie Schoevaars and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Molecular And Supramolecular Information Processing
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Author : Evgeny Katz
language : en
Publisher: John Wiley & Sons
Release Date : 2013-02-14
Molecular And Supramolecular Information Processing written by Evgeny Katz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-14 with Science categories.
Edited by a renowned and much cited chemist, this book covers the whole span of molecular computers that are based on non-biological systems. The contributions by all the major scientists in the field provide an excellent overview of the latest developments in this rapidly expanding area. A must-have for all researchers working on this very hot topic. Perfectly complements Biomolecular Information Processing, also by Prof. Katz, and available as a two-volume set.
Molecular Switches
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Author : A. Malcolm Campbell
language : en
Publisher:
Release Date : 2016-04-21
Molecular Switches written by A. Malcolm Campbell and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Science categories.
This book introduces the concept of emergent properties, which are unexpected traits found only when two or more biological components interact. Experimental evidence of several emergent properties explains how hemoglobin can act like a high affinity oxygen carrier some times and then switch to a low affinity carrier exactly when and where it should. The second example presents how one particular virus determines whether it should stay latent within its host or whether it should kill its host and spread its progeny into the environment. The final example looks at the surprising properties that emerge as a consequence of random behaviors at the molecular level. It is unlikely that many people are aware of these unexpected behaviors that come from non-living molecules based on their structures.
Photofunctionalization Of Molecular Switch Based On Pyrimidine Ring Rotation In Copper Complexes
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Author : Michihiro Nishikawa
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-16
Photofunctionalization Of Molecular Switch Based On Pyrimidine Ring Rotation In Copper Complexes written by Michihiro Nishikawa and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-16 with Science categories.
This book provides a detailed description of photofunctionalization of molecular switch based on pyrimidine ring rotational isomerization in copper complexes bearing two bidentate ligands. The most important features of this work focus on the properties associated with the rotational isomerization based on the two possible coordination geometries at the copper center derived from two nitrogen atoms on the unsymmetrically substituted pyrimidine ring. The functions of systems such as dual emission and redox potential switching based on photo-driven rotation will be of particular interest to readers. Both the functions and the procedures for proving these phenomena are beneficial for the development of more functionalized systems based on material science, molecular science, nanoscience, nanotechnology, electrochemistry, photochemistry, coordination chemistry, physical chemistry, and related disciplines. The finding elucidated here holds promise for handling the photoprocesses of metal complexes, valid for both applications and novel properties. This system is expected make it possible to extract an electrochemical potential response from molecular switches, aiming to simulate the five senses of human beings at a single molecular level.
Molecular And Supramolecular Information Processing
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Author : Evgeny Katz
language : en
Publisher:
Release Date : 2012
Molecular And Supramolecular Information Processing written by Evgeny Katz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Chemistry, Physical and theoretical categories.
Molecular Photoswitches
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Author : Zbigniew L. Pianowski
language : en
Publisher: John Wiley & Sons
Release Date : 2022-06-01
Molecular Photoswitches written by Zbigniew L. Pianowski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-01 with Science categories.
A comprehensive overview about the emerging field of photoswitches and their applications in materials science and biology Molecular Photoswitches guides the reader through the basic molecular structures of photochromic compounds and their applications in the area of photoresponsive materials as well as in the biological context. The initial chapters describe individual classes of molecular photoswitches, introducing their principles of photochromism, typical switching wavelengths, thermal stability of photoisomers and other key information, which is ordinarily spread in the literature. These classes comprise i.a. azobenzenes, diazocines, arylazoheterocycles, arylhydrazones, indigoids, photochromic imines, or acylhydrazones. The book also covers: Catalysis with molecular switches Applications in photochromic porous materials, liquid crystals, or nanoparticles Light-responsive molecular machines, logic devices, and molecular magnets Photomodulation of biological systems: photoswitchable biopolymers, lightmodulated antibiotics, cytotoxins, ion channel inhibitors, light-propelled artificial muscles, and computationally designed photochromic proteins This two-volume work is a valuable guide for researchers and non-experts working in the field of photochemistry, organic chemistry, catalysis, materials science, biology, and medicine.
Chiroptical Molecular Switches
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Author : Anne Marie Schoevaars
language : en
Publisher:
Release Date : 1998
Chiroptical Molecular Switches written by Anne Marie Schoevaars and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.