The Mutations
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The Mutations
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Author : Jorge Comensal
language : en
Publisher: Macmillan + ORM
Release Date : 2019-11-12
The Mutations written by Jorge Comensal and has been published by Macmillan + ORM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-12 with Fiction categories.
"Jorge Comensal's The Mutations oscillates masterfully between comedy and tragedy, gathering up in its pages a stupendous panoply of characters before whom the reader is never sure whether to smile in sympathy or pity."—Fernando Aramburu, author of Homeland Ramón Martinez is a militant atheist, successful lawyer, and conventional family man. But all of that changes when cancer of the tongue deprives him of the source of his power and livelihood: speech. The Mutations, by Jorge Comensal, is a comedy tracing the metastasis of Ramón’s cancer through his body and in the lives of his family members, colleagues, and doctors, dissecting the experience of illness and mapping the relationships both strengthened and frayed by its wake. Mateo and Paulina, his teenage children, struggle with the temptations of masturbation and binge eating, respectively. Ramón’s melancholic oncologist is haunted by the memory of a young patient whom he was unable to save. His selfish pathologist believes Ramón’s tumor holds the key to a major scientific breakthrough. And then there’s Elodia, Ramón’s pious maid, who brings him a foulmouthed parrot as a birthday gift. This lewd bird becomes Ramón’s companion, confidant, and unlikely double. Paying homage to the works of forebears such as Sontag, Didion, Flaubert, and Tolstoy, and filled with a rough-hewn poetry of regret, rage, and finally resignation, The Mutations offers a profound but funny cross section of modern Mexican life, as well as a bold treatment of an unspeakable yet universal reality
Mutation
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Author : Michael McBride
language : en
Publisher: Pinnacle Books
Release Date : 2020-09-29
Mutation written by Michael McBride and has been published by Pinnacle Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-29 with Fiction categories.
“McBride writes with the perfect mixture of suspense and horror that keeps the reader on edge.” —Examiner IT LIVES. In a research hangar in Virginia, a Unit 51 team studies an ancient but long-dormant virus that can transform human physiology—and turn it into something else. . . IT MUTATES. In the Amazon rainforest, a newly evolving life form known as Subject Z acquires the ability to think conceptually, build elaborate traps, create new carriers—and spawn a new race . . . IT SPREADS. In Mexico and Turkey, the men and women of Unit 51 race to uncover a global link between the mutations: a connection as ancient as the oldest tombs on earth—and as alien and unknowable as the universe itself. But time is running out. The infected are growing in number. And the nightmare is going viral . “This novel is for everyone who’s still a little scared of the dark . . . a very good sci-fi/thriller.” —The Oklahoman on Subhuman “Thriller powerhouse McBride begins his Unit 51 series . . . evoking feelings of shock and terror.” —Publishers Weekly on Subhuman Visit us at www.kensingtonbooks.com
The Mutations
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Author : Jorge Comensal
language : en
Publisher: Macmillan + ORM
Release Date : 2019-11-12
The Mutations written by Jorge Comensal and has been published by Macmillan + ORM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-12 with Fiction categories.
"Jorge Comensal's The Mutations oscillates masterfully between comedy and tragedy, gathering up in its pages a stupendous panoply of characters before whom the reader is never sure whether to smile in sympathy or pity."—Fernando Aramburu, author of Homeland Ramón Martinez is a militant atheist, successful lawyer, and conventional family man. But all of that changes when cancer of the tongue deprives him of the source of his power and livelihood: speech. The Mutations, by Jorge Comensal, is a comedy tracing the metastasis of Ramón’s cancer through his body and in the lives of his family members, colleagues, and doctors, dissecting the experience of illness and mapping the relationships both strengthened and frayed by its wake. Mateo and Paulina, his teenage children, struggle with the temptations of masturbation and binge eating, respectively. Ramón’s melancholic oncologist is haunted by the memory of a young patient whom he was unable to save. His selfish pathologist believes Ramón’s tumor holds the key to a major scientific breakthrough. And then there’s Elodia, Ramón’s pious maid, who brings him a foulmouthed parrot as a birthday gift. This lewd bird becomes Ramón’s companion, confidant, and unlikely double. Paying homage to the works of forebears such as Sontag, Didion, Flaubert, and Tolstoy, and filled with a rough-hewn poetry of regret, rage, and finally resignation, The Mutations offers a profound but funny cross section of modern Mexican life, as well as a bold treatment of an unspeakable yet universal reality
Mutations In Human Genetic Disease
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Author : David Cooper
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-10-12
Mutations In Human Genetic Disease written by David Cooper and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-12 with Medical categories.
Different types of mutation can vary in size, from structural variants to single base-pair substitutions, but what they all have in common is that their nature, size and location are often determined either by specific characteristics of the local DNA sequence environment or by higher order features of the genomic architecture. The genomes of higher organisms are now known to contain "pervasive architectural flaws" in that certain DNA sequences are inherently mutation prone by virtue of their base composition, sequence repetitivity and/or epigenetic modification. In this volume, a number of different authors from diverse backgrounds describe how the nature, location and frequency of different types of mutation causing inherited disease are shaped in large part, and often in remarkably predictable ways, by the local DNA sequence environment.
Technologies For Detection Of Dna Damage And Mutations
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Author : G.P. Pfeifer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Technologies For Detection Of Dna Damage And Mutations written by G.P. Pfeifer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
Man-made carcinogens, natural genotoxic agents in the environment, as well as ionizing and ultraviolet radiation can damage DNA and are a constant threat to genome integrity. Throughout the evolution oflife, complex DNA repair systems have developed in all living organisms to cope with this damage. Unrepaired DNA lesions can promote genetic alterations (mutations) that may be linked to an altered phenotype, and, if growth-controlling genes are involved, these mutations can lead to cell transformation and the development of malignant tumors. Proto oncogenes and tumor suppressor genes may be critical targets for DNA damaging agents. In a number of animal model systems, correlations between exposure to a carcinogen, tumor develop ment, and genetic changes in tumor DNA have been established. To understand mutagenesis processes in more detail at the molecular level, we need to know the type and frequency of DNA adducts within cells, their distribution along genes and specific DNA sequences, as well as the rates at which they are repaired. We also need to know what types of mutations are produced and which gene positions are most prone to mutagenesis. This book provides a collection of techniques that are useful in mutagenesis research. The book is divided into three parts. In Part I, methods for DNA damage and repair analysis are provided.
Modelling The Short Qt Syndrome Gene Mutations
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Author : Ismail Adeniran
language : en
Publisher: Springer
Release Date : 2014-06-11
Modelling The Short Qt Syndrome Gene Mutations written by Ismail Adeniran and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-11 with Science categories.
The Short QT Syndrome (SQTS) is characterized by abbreviated QT intervals on the electrocardiogram, increased risk of cardiac arrhythmias and sudden death. Although several gene mutations have been identified in SQT patients, the role of these mutations in promoting arrhythmogenesis is still not completely understood. Consequently, this thesis employs multidisciplinary approaches to develop a 3D virtual heart, which is then used to elucidate how the short QT syndrome facilitates and maintains ventricular arrhythmias and to determine its effects on ventricular mechanical contraction. The findings in this thesis provide a comprehensive and mechanistic explanation for a number of gene mutations associated with potassium channels in terms of susceptibility to arrhythmia. The multiphysics models developed provide a powerful platform for identifying the root causes of various arrhythmias and investigating therapeutic interventions for these diseases. The thesis was examined by Prof. Chris Huang of the University of Cambridge, the most authoritative figure in cardiac electrophysiology, who has described the work as “outstanding.”
Technologies For Detecting Heritable Mutations In Human Beings
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Author :
language : en
Publisher: DIANE Publishing
Release Date : 1986
Technologies For Detecting Heritable Mutations In Human Beings written by and has been published by DIANE Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Medical genetics categories.
Another Possible Cause Of Spontaneous Mutations
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Author : Robert L. Brent
language : en
Publisher:
Release Date : 1954
Another Possible Cause Of Spontaneous Mutations written by Robert L. Brent and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1954 with Carbon categories.
Handbook Of Mouse Mutations With Skin And Hair Abnormalities
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Author : John P. Sundberg
language : en
Publisher: CRC Press
Release Date : 2020-08-26
Handbook Of Mouse Mutations With Skin And Hair Abnormalities written by John P. Sundberg and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-26 with Medical categories.
Handbook of Mouse Mutations with Skin and Hair Abnormalities presents 48 mouse mutations that are all available to the biomedical community. Many of the mouse mutations with dermatological diseases are reviewed and illustrated in detail. This popular reference book gives you a single source to use when determining which mouse mutation will best serve your needs as a biomedical tool for sophisticated research projects. The book also includes an overview of domestic animal genodermatoses to provide alternatives to mouse models that do not exist or to complement those that do. A detailed section written by renowned experts compares the biology of human and mouse skin and skin diseases in the areas of development and the use of animal models, mammalian genetics, keratin biochemistry, epidermal and hair follicle cycles and kinetics, cytokines and growth factors, keratinocyte culture systems, cutaneous carcinogenesis, cutaneous immune system, and skin changes associated with mutations of the endocrine system.
China S Economic Gene Mutations
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Author : Zhaoguang Hu
language : en
Publisher: Springer
Release Date : 2015-07-30
China S Economic Gene Mutations written by Zhaoguang Hu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-30 with Business & Economics categories.
The book focuses on low-carbon issues and China’s economy, which is analyzed from the perspective of electricity economics. It proposes the novel concept of an “economic gene” to reflect certain characteristics of the economy. The gene mapping of China’s economy has been studied based on production functions with electricity. Economic mutations have also been studied with the aim of diagnosing problems in the economy. Two such mutations have occurred in China since 1978, the most recent being in 2012 and no further mutation is expected until 2025. The book describes the inherent quality of China’s economy from 2012 to 2025, and how mechanism reforms would greatly improve marginal representative factor productivity in this period. The agents response equilibrium (ARE) approach to simulate national economy, based on multi-agent technology is proposed. Another cornerstone of the model is the input-output table. Simulated input-output tables from 2011 to 2025 are provided in the book. This book provides recommendations for policy makers and advisors, and is a valuable resource for researchers in the fields of economics, public policies, low-carbon development, electricity and energy. It also provides insights into China’s economic development.