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The Pharmacology Of Kratom And Its Alkaloids


The Pharmacology Of Kratom And Its Alkaloids
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The Pharmacology Of Kratom And Its Alkaloids


The Pharmacology Of Kratom And Its Alkaloids
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Author : Oliver Grundmann
language : en
Publisher: Frontiers Media SA
Release Date : 2022-03-28

The Pharmacology Of Kratom And Its Alkaloids written by Oliver Grundmann and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-28 with Science categories.




Kratom And Other Mitragynines


Kratom And Other Mitragynines
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Author : Robert B. Raffa
language : en
Publisher: CRC Press
Release Date : 2014-10-29

Kratom And Other Mitragynines written by Robert B. Raffa and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Medical categories.


Opioids such as morphine, codeine, and oxycodone are extracts or analogs isolated from a single source: the opium poppy. For a long time, it was believed to be nature’s only source of opioids. But it now appears that biological diversity has evolved an alternative source of opioid compounds—those derived from the plant Mitragyna speciosa. This plant, known as Kratom in Thailand or Biak-Biak in Malaysia, has long been used locally as treatment for pain, fever reduction, diarrhea, and even depression. Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source presents an introduction to the chemical and biological properties of alkaloids isolated from M. speciosa as well as their synthetic analogs. The book covers various topics including phytochemistry, medicinal chemistry, and pharmacology. Current research, analgesic effects, and addiction potential are also discussed. As the first extensive text on the basic science and clinical use of Kratom, the book provides readers with a concise yet comprehensive introduction to nature’s "other opioid."



Optimization In Drug Discovery


Optimization In Drug Discovery
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Author : Gary W. Caldwell
language : en
Publisher: Humana
Release Date : 2016-08-23

Optimization In Drug Discovery written by Gary W. Caldwell and has been published by Humana this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-23 with Medical categories.


Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve “drug-like” characteristics in addition to efficacy properties and good safety profiles of drug candidates. Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.



Behavioral Pharmacology Of Drug Abuse Current Status


Behavioral Pharmacology Of Drug Abuse Current Status
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Author :
language : en
Publisher: Academic Press
Release Date : 2022-03-25

Behavioral Pharmacology Of Drug Abuse Current Status written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-25 with Medical categories.


Behavioral Pharmacology of Drug Abuse: Current Status, Volume 93 provides an update on our current understanding of animal and human behavioral pharmacology in major classes of drugs of abuse, including nicotine, alcohol, opioids, psychostimulants, and hallucinogens, drug-environment interactions, neurochemical mechanisms and medications developments. This volume updates the field of behavioral pharmacology based on new knowledge gained in the past decade. Provides accurate and updated reviews from selected experts on covered topics Presents useful graphic material for ease of reading Covers a wide range of topics that are highly integral to offer a panoramic view of the field of behavioral pharmacology



Alkaloids


Alkaloids
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Author : Margaret F. Roberts
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Alkaloids written by Margaret F. Roberts and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Science categories.


Not since the late 1970s has a single work presented the biology of this heterogenous group of secondary alkaloids in such depth. Alkaloids, a unique treatise featuring leaders in the field, presents both the historical use of alkaloids and the latest discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and current medicinal use . Highlights include chapters on the chemical ecology of alkaloids in host-predator interactions, and on the compartmentation of alkaloids synthesis, transport, and storage. Extensive cross-referencing in tabular format makes this volume an excellent reference.



Addictive Substances And Neurological Disease


Addictive Substances And Neurological Disease
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Author : Ronald Ross Watson
language : en
Publisher: Academic Press
Release Date : 2017-02-18

Addictive Substances And Neurological Disease written by Ronald Ross Watson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-18 with Medical categories.


Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances



Medical Toxicology Of Drug Abuse


Medical Toxicology Of Drug Abuse
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Author : Donald G. Barceloux
language : en
Publisher: John Wiley & Sons
Release Date : 2012-02-03

Medical Toxicology Of Drug Abuse written by Donald G. Barceloux and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-03 with Science categories.


This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.



Novel Psychoactive Substances


Novel Psychoactive Substances
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Author : Ornella Corazza
language : en
Publisher: Springer
Release Date : 2017-08-09

Novel Psychoactive Substances written by Ornella Corazza and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-09 with Business & Economics categories.


In light of the recent emergence of Novel Psychoactive Substances (NPS) on a global scale, this book provides a timely analysis of the social and economic impact of the NPS phenomenon, and of the global policy and regulatory responses to it. It presents the first comprehensive overview of the international regulation, policy and market structure of the NPS phenomenon, offering a guide to inform legislative discussions and demonstrating from a comparative perspective the different approaches used to address the rise of NPS to date. It covers topics such as organized crime, drug markets, clinical evidence on NPS, and different regulatory approaches also in less explored settings such as prisons and sport environments. Overall, this highly informative and well-structured repository of different experiences with NPS policy, law and regulation offers an essential primary source of evidence for anyone interested in the area of drug and NPS policy, health economics and p ublic health.



Novel Psychoactive Substances


Novel Psychoactive Substances
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Author : Paul I. Dargan
language : en
Publisher: Academic Press
Release Date : 2021-09-06

Novel Psychoactive Substances written by Paul I. Dargan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-06 with Medical categories.


Novel Psychoactive Substances: Classification, Pharmacology and Toxicology, Second Edition provides readers with a comprehensive examination on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." The book covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance and a discussion of their associated acute and chronic harm and toxicity. This second edition addresses drugs new to the scene, with completely updated and revised chapters. Written by international experts in the field, this multi-authored book is an essential reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. Includes chapters written by international experts in the field Presents a comprehensive overview on the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene, including amphetamines and the synthetic cannabinoid receptors in ‘spice’ and ‘K2’



Annual Plant Reviews Functions And Biotechnology Of Plant Secondary Metabolites


Annual Plant Reviews Functions And Biotechnology Of Plant Secondary Metabolites
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Author : Michael Wink
language : en
Publisher: John Wiley & Sons
Release Date : 2010-01-26

Annual Plant Reviews Functions And Biotechnology Of Plant Secondary Metabolites written by Michael Wink and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-01-26 with Science categories.


This important volume commences with an overview of the modes of action of defensive secondary metabolites, followed by detailed surveys of chemical defense in marine ecosystems, the biochemistry of induced defense, plant-microbe interactions and medical applications. A chapter is also included covering biotechnological aspects of producing valuable secondary metabolites in plant cell and organ cultures. This is a comprehensive and fully updated new edition, edited by Professor Michael Wink and including contributions from many internationally acknowledged experts in the field.