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The Physical Foundation Of Protein Architecture


The Physical Foundation Of Protein Architecture
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The Physical Foundation Of Protein Architecture


The Physical Foundation Of Protein Architecture
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Author : Nobuhiko Saito
language : en
Publisher: World Scientific
Release Date : 2001

The Physical Foundation Of Protein Architecture written by Nobuhiko Saito and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.


A protein requires its own three-dimensional structure for its biological activity. If a chemical agent is added, the biological activity is lost, and the three dimensional structure is destroyed to become a random coil state. But when the chemical agent is removed, the biological activity is recovered, implying that the random coil state turns back into the original complex structure spontaneously. This is an astonishing event. The Physical Foundation of Protein Architectur e is intended to solve this mystery from the physicochemical basis by elucidating the mechanism of various processes in protein folding. The main features of protein folding are shown to be described by the island model with long range hydrophobic interaction which is capable of finding the specific residue, and the lampshade criterion for disulfide bonding. Various proteins with known structure are refolded, with the purpose of uncovering the mechanism of protein folding. In addition, ab initio method for predicting protein structure from its amino acid sequence is proposed. Sample Chapter(s). Chapter 1.1: Introduction (278 KB). Chapter 1.2: Helix-Coil Transition in Polypeptide (335 KB). Chapter 1.3: Some Aspects of Protein Folding (986 KB). Contents: Generalities: Helix-Coil Transition in Polypeptide; Some Aspects of Protein Folding; Mechanism of Protein Folding: Island Model; -Helical Proteins; Lysozyme and Phospholipase; Bovine Pancreatic Trypsin Inhibitor; Flavodoxin and Thioredoxin; Ferredoxin; Folding of a Protein of Unknown Structure: Ab Initio Method of Prediction of Protein Structure; Search for the Conformation of Minimum Energy; Topics Related to Protein Structures: Phase Transition; Module; Molecular Chaperones; Membrane Proteins; Structure Prediction Based on Protein Data. Readership: Advanced graduate students and researchers in the biosciences.



The Physical Foundation Of Protein Architecture


The Physical Foundation Of Protein Architecture
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Author : Yukio Kobayashi
language : en
Publisher: World Scientific
Release Date : 2001-11-29

The Physical Foundation Of Protein Architecture written by Yukio Kobayashi and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-29 with Science categories.


A protein requires its own three-dimensional structure for its biological activity. If a chemical agent is added, the biological activity is lost, and the three dimensional structure is destroyed to become a random coil state. But when the chemical agent is removed, the biological activity is recovered, implying that the random coil state turns back into the original complex structure spontaneously. This is an astonishing event. The Physical Foundation of Protein Architecture is intended to solve this mystery from the physicochemical basis by elucidating the mechanism of various processes in protein folding. The main features of protein folding are shown to be described by the island model with long range hydrophobic interaction which is capable of finding the specific residue, and the lampshade criterion for disulfide bonding. Various proteins with known structure are refolded, with the purpose of uncovering the mechanism of protein folding. In addition, ab initio method for predicting protein structure from its amino acid sequence is proposed.



Amino Acids Peptides And Proteins


Amino Acids Peptides And Proteins
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Author : J S Davies
language : en
Publisher: Royal Society of Chemistry
Release Date : 2007-10-31

Amino Acids Peptides And Proteins written by J S Davies and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-31 with Science categories.


In an ever-increasing domain of activity, Amino Acids, Peptides and Proteins provides an annual compilation of the world's research effort into this important area of biological chemistry. Volume 34 provides a review of literature published during 2001. Comprising a comprehensive review of significant developments at this biology/chemistry interface, each volume opens with an overview of amino acids and their applications. Work on peptides is reviewed over several chapters, ranging from current trends in their synthesis and conformational and structural analysis, to peptidomimetics and the discovery of peptide-related molecules in nature. The application of advanced techniques in structural elucidation is incorporated into all chapters, whilst periodic chapters on metal complexes of amino acids, peptides and beta-lactams extend the scope of coverage. Efficient searching of specialist topics is facilitated by the sub-division of chapters into discrete subject areas, allowing annual trends to be monitored. All researchers in the pharmaceutical and allied industries, and at the biology/chemistry interface in academia will find this an indispensable reference source. Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.



Electrospinning And Electrospraying


Electrospinning And Electrospraying
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Author : Sajjad Haider
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-12-11

Electrospinning And Electrospraying written by Sajjad Haider and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-11 with Science categories.


This book focuses on the recent advancements in the process parameters, research, and applications of electrospinning and electrospraying. The first chapter introduces the techniques and the effect of the parameters on the morphology of the nanofiber and nanoparticles and then the subsequent chapters focus on the applications of these techniques in different areas. This book will attract a broad audience including postgraduate students and industrial and academic investigators in sciences and engineering who wish to enhance their understanding of the emerging technologies and use this book as reference.



Multiscale Approaches To Protein Modeling


Multiscale Approaches To Protein Modeling
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Author : Andrzej Kolinski
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-13

Multiscale Approaches To Protein Modeling written by Andrzej Kolinski and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-13 with Science categories.


The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dynamics, folding mechanisms and macromolecular interactions. It approaches span a wide range of the levels of coarse-grained representations, various sampling techniques and variety of applications to biomedical and biophysical problems. This book is intended to be used as a reference book for those who are just beginning their adventure with biomacromolecular modeling but also as a valuable source of detailed information for those who are already experts in the field of biomacromolecular modeling and in related areas of computational biology or biophysics.



Journal Of The Physical Society Of Japan


Journal Of The Physical Society Of Japan
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Author :
language : en
Publisher:
Release Date : 2007

Journal Of The Physical Society Of Japan written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Physics categories.




Elements Of Physical Chemistry And Chemical Physics


Elements Of Physical Chemistry And Chemical Physics
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Author : Pasquale De Marco
language : en
Publisher: Pasquale De Marco
Release Date :

Elements Of Physical Chemistry And Chemical Physics written by Pasquale De Marco and has been published by Pasquale De Marco this book supported file pdf, txt, epub, kindle and other format this book has been release on with Science categories.


Embark on a journey into the captivating world of physical chemistry and chemical physics with this comprehensive and engaging volume. Delve into the fundamental principles that govern the behavior of matter and energy, and uncover the intricate relationships between microscopic and macroscopic phenomena. This book provides a thorough exploration of the key concepts and theories that underpin modern chemistry and physics, making them accessible to students, researchers, and professionals alike. With its clear and engaging writing style, the book guides readers through complex topics, offering a deep understanding of the underlying principles that shape our physical world. Discover the fascinating realm of quantum mechanics, where particles exhibit both wave-like and particle-like behavior, and delve into the intricacies of thermodynamics, the study of energy and its transformations. Explore the dynamics of chemical reactions, unraveling the factors that influence their rates and mechanisms. Journey into the realm of electrochemistry and solid state chemistry, where ions and electrons dance in solution and materials exhibit unique electrical and magnetic properties. Investigate the intricate world of surface chemistry and colloids, where molecules and particles interact at interfaces, shaping the properties of complex fluids. Finally, venture into the frontiers of physical chemistry and chemical physics, where cutting-edge research is pushing the boundaries of our knowledge. Explore the exciting possibilities of quantum information and computing, femtochemistry, single-molecule chemistry, and supramolecular chemistry. With its comprehensive coverage, in-depth analysis, and engaging writing style, this book serves as an invaluable resource for anyone seeking to deepen their understanding of physical chemistry and chemical physics. Whether you are a student seeking a deeper grasp of the fundamental principles, a researcher delving into the intricacies of matter and energy, or a professional seeking to stay abreast of the latest advancements, this book is an essential addition to your library. If you like this book, write a review!



Coarse Grained Modeling Of Biomolecules


Coarse Grained Modeling Of Biomolecules
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Author : Garegin A. Papoian
language : en
Publisher: CRC Press
Release Date : 2017-10-30

Coarse Grained Modeling Of Biomolecules written by Garegin A. Papoian and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-30 with Science categories.


"The chapters in this book survey the progress in simulating biomolecular dynamics.... The images conjured up by this work are not yet universally loved, but are beginning to bring new insights into the study of biological structure and function. The future will decide whether this scientific movement can bring forth its Picasso or Modigliani." –from the Foreword by Peter G. Wolynes, Bullard-Welch Foundation Professor of Science, Rice University This book highlights the state-of-art in coarse-grained modeling of biomolecules, covering both fundamentals as well as various cutting edge applications. Coarse-graining of biomolecules is an area of rapid advances, with numerous new force fields having appeared recently and significant progress made in developing a systematic theory of coarse-graining. The contents start with first fundamental principles based on physics, then survey specific state-of-art coarse-grained force fields of proteins and nucleic acids, and provide examples of exciting biological problems that are at large scale, and hence, only amenable to coarse-grained modeling. Introduces coarse-grained models of proteins and nucleic acids. Showcases applications such as genome packaging in nuclei and understanding ribosome dynamics Gives the physical foundations of coarse-graining Demonstrates use of models for large-scale assemblies in modern studies Garegin A. Papoian is the first Monroe Martin Associate Professor with appointments in the Department of Chemistry and Biochemistry and the Institute for Physical Science and Technology at the University of Maryland.



Bioinformatics In Rice Research


Bioinformatics In Rice Research
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Author : Manoj Kumar Gupta
language : en
Publisher: Springer Nature
Release Date : 2021-09-24

Bioinformatics In Rice Research written by Manoj Kumar Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-24 with Science categories.


This book provides an up-to-date review of classic and advanced bioinformatics approaches and their utility in rice research. It summarizes databases and tools for analyzing DNA, proteins and gene expression profiles, mapping genetic variations, annotation of protein and RNA molecules, phylogenetic analysis, and pathway enrichment. In addition, it presents high-throughput technologies that are widely used to provide deep insights into the genetic architecture of important traits in the rice genome. The book subsequently discusses techniques for identifying RNA-protein, DNA-protein interactions, and molecular markers, including SNP and microsatellites, in the contexts of rice breeding and genetics. Lastly, it explores various tools that are used to identify and characterize non-coding RNA in rice and their potential role in rice research.



Structure Dynamics And Function Of Biomolecules


Structure Dynamics And Function Of Biomolecules
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Author : Anders Ehrenberg
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Structure Dynamics And Function Of Biomolecules written by Anders Ehrenberg and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


This is a collection of papers presented and discussed at the first EBSA workshop held at Saltsj6baden outside stockholm in Sweden, July 6-10, 1986. The common theme of these papers is dynamics of biomolecules, and how the dynamics depends on the molecular structure and organi zation, and connects to and determines the biological function. This is a rapidly expanding field of research which combines many different aspects of molecular bio physics. Much material is new and presented for the first time. Even if the work so far has been of the kind that is usually called basic research, practical applications are clearly indicated in some articles, and are waiting around the corner in several other cases. At the workshop only one third of the time was used for the formal presentations and two thirds for discussion. To this should also be added discussions during the poster sessions. During these lively and unrecorded discussions fresh viewpoints emerged and new ideas were created. Ad mittedly, our knowledge at present is only fragmentary but when pieces of the puzzle are brought together at a workshop or in a publication of this kind more extended and sometimes unexpected contours and shapes become vi sible. It is our hope that this rapid publication of camera-ready manuscripts will transfer some of the spi rit at the workshop to the reader, and in his or her institute or laboratory initiate further discussions, bring forward more ideas and start new experimental ap roaches.