The Prostaglandin System
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The Prostaglandin System
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Author : F. Berti
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
The Prostaglandin System written by F. Berti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Prostaglandin research is one of the most explosive fields in the biological science, and there have been a number of international symposia on this subject. In planning the second Advanced Course in Erice (Sicily) at the "Ettore Majorana" center it was realized that large congresses might not represent the best way to facilitate communication within specialized areas of biologic and medical research. In fact small meetings where in depth discussion is confined to a limited number of scientists, are now generally considered successful vehicles of scientific information. With this in mind, we made an effort in collecting a number of experts in both experimental and clinical use of these important arachidonate metabolites. We have been very fortunate in bringing together a faculty of international authorities who contributed to the course with brilliant presentations and lively discussion. Thus, this book represents an up-to-date overview of the physiology and pharmacology of different products derived from arachidonic acid metabolism, associated with outstanding suggestions of their clinical potential. It is our hope that from this Advanced Course, and its resulting publication, new ideas concerning the physio pathological role of these compounds will arise together with new directions for future research. We are deeply indebted to NATO for its interest and generous support which made this Second Course a reality.
The Prostaglandin System
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Author : F. Berti
language : en
Publisher:
Release Date : 2014-01-15
The Prostaglandin System written by F. Berti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-15 with categories.
The Prostaglandin System Endoperoxides Prostacyclin And Thromboxanes
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Author : Giampaolo P. Velo
language : en
Publisher:
Release Date : 1981
The Prostaglandin System Endoperoxides Prostacyclin And Thromboxanes written by Giampaolo P. Velo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Peroxides categories.
The Prostaglandins
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Author : Peter Ramwell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
The Prostaglandins written by Peter Ramwell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.
The Prostaglandins
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Author : Sultan M.M. Karim
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Prostaglandins written by Sultan M.M. Karim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The voluminous literature on prostaglandins includes some excellent reviews. For some time however, there has been a need for the collection in one volume of information from individual experts actively engaged in different aspects of prostaglandin research. This book is an attempt to fulfil that need. In view of the expanding interest and ever-growing accumulation of data of the various effects of prostaglandins it is hoped to revise the book and bring it up-to-date periodically. The largest section is that on reproduction, in which field progress in research and clinical applications thereof have been, and are, of great significance particularly in the area of popula tion control. This is not to decry the skill and efforts of investi gators in other aspects of prostaglandin activity nor the potential biological or therapeutic importance of their findings. In this context, what may appear to be omissions are individual sections on prostaglandin activity in the central nervous system, in the eye and as mediators of the inflammatory response. These are considered in the chapter on General Pharmacology of the Prostaglandins not because they might be considered to be of lesser impact and significance but in order to achieve a rapid publication of the book. S. M. M. KARIM Kampala, Uganda. January 1972. Acknowledgements Tables and Figures previously published are, in general, acknowledged by the reference in the legends and I am grateful to the authors, editors and publishers for their per mission.
Prostaglandins And The Kidney
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Author : Michael Dunn
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Prostaglandins And The Kidney written by Michael Dunn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
In June, 1981, we conducted a two day international symposium in Rome devoted to original scientific presentations on arachidonic acid metabolism in the kidney. Scientists from 20 countries were represented either in the general scientific program or in the poster presentation. This book does not represent the proceedings of this international gathering, but rather the edited manuscripts specifically prepared as sum maries of the scientific presentations. We feel that the timeliness and originality of the contributions as well as the need for a compilation of existing work on prosta glandins, thromboxane, and the kidney warrant this publication. The meetings would have been impossible without the generous and substantial support of the Italian government, the National Institutes of Health, United States Public Health Service, and Merck Sharp & Dohme International. Supplementary support was also received from Ciba Geigy S. p. A., Ente Fiuggi, Farmitalia Carlo Erba S. p. A., Glaxo Laboratori S. p. A., Hoechst Italia S. p. A., Leo Pharmaceutical Products, Pfizer Italiana S. p. A., Sigm? Tau S. p. A., Squibb S. p. A., The Upjohn Company, Wellcome Italia S. p. A., and Burroughs Wellcome Company. The efficient organization of the symposium was largely attributable to the superb efforts of Elisabeth Mutschlechner and Miki Scarinci of C.K. International, Rome. Linda Goldberg provided expert and invaluable editorial and secretarial assistance in the organization of this book. The book is divided into four major sections comprising: I.
Fluorine And Health
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Author : Alain Tressaud
language : en
Publisher: Elsevier
Release Date : 2008-06-06
Fluorine And Health written by Alain Tressaud and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-06 with Medical categories.
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. New approach of topics involving chemistry, biology and medicinal techniques Transdisciplinar papers on fluoride products Importance of fluoride products in health Updated data on specific topics
Advances In Prostaglandin And Thromboxane Research Prostoglandins And The Cardiovascular System
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Author : Bengt Samuelsson
language : en
Publisher:
Release Date : 1982
Advances In Prostaglandin And Thromboxane Research Prostoglandins And The Cardiovascular System written by Bengt Samuelsson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Cardiovascular system categories.
Prostaglandins And Other Eicosanoids In The Cardiovascular System
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Author : Karsten Schrör
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1985
Prostaglandins And Other Eicosanoids In The Cardiovascular System written by Karsten Schrör and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medical categories.
The Prostaglandins
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Author : Peter Ramwell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
The Prostaglandins written by Peter Ramwell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
