The Prostaglandins
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The Prostaglandins
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Author : Sultan M.M. Karim
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Prostaglandins written by Sultan M.M. Karim and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The voluminous literature on prostaglandins includes some excellent reviews. For some time however, there has been a need for the collection in one volume of information from individual experts actively engaged in different aspects of prostaglandin research. This book is an attempt to fulfil that need. In view of the expanding interest and ever-growing accumulation of data of the various effects of prostaglandins it is hoped to revise the book and bring it up-to-date periodically. The largest section is that on reproduction, in which field progress in research and clinical applications thereof have been, and are, of great significance particularly in the area of popula tion control. This is not to decry the skill and efforts of investi gators in other aspects of prostaglandin activity nor the potential biological or therapeutic importance of their findings. In this context, what may appear to be omissions are individual sections on prostaglandin activity in the central nervous system, in the eye and as mediators of the inflammatory response. These are considered in the chapter on General Pharmacology of the Prostaglandins not because they might be considered to be of lesser impact and significance but in order to achieve a rapid publication of the book. S. M. M. KARIM Kampala, Uganda. January 1972. Acknowledgements Tables and Figures previously published are, in general, acknowledged by the reference in the legends and I am grateful to the authors, editors and publishers for their per mission.
The Prostaglandins
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Author : Peter Ramwell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
The Prostaglandins written by Peter Ramwell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
There is much evidence to suggest that prostaglandins may have a physiological role to play in the control of thyroid gland metabolism, although the precise nature of this role remains to be defined. Prostaglandins have been found in normal thyroid tissue, and there is evidence of increased levels in some, but not all, cases of medullary carcinoma of the thyroid. which may account for the associated diarrhea. Exogenous prostaglandins, like TSH, bind to thyroid plasma mem branes, stimulate the adenylate cyclase-cyclic AMP system, thyroid hormone secretion, iodide organification, colloid droplet formation, glucose oxidation, and 32p incorporation into phospholipids. Prosta glandins of the E series are the most potent, although their maximal effects are generally less than the maximal effects of TSH. The interrelationships existing between TSH and prostaglandins have been the subject of intensive investigation, but as yet no one uni fying concept has emerged. TSH and prostaglandins have been shown to occupy different receptors on the thyroid plasma membrane. Al though TSH can increase intracellular prostaglandin levels, probably as a result of increased synthesis, prostaglandins do not appear to be essential intermediates in TSH action on adenylate cyclase. The pos sibility that prostaglandins are part of a negative feedback system con trolling TSH action is, as yet, a tentative hypothesis, and further work will be required to unravel the interrelationships between these sub stances that now appear to be far more complex than has been envisaged thus far.
The Prostaglandins
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Author : Peter Ramwell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
The Prostaglandins written by Peter Ramwell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.
The Prostaglandins In Human Reproduction
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Author : Mostyn P. Embrey
language : en
Publisher:
Release Date : 1975
The Prostaglandins In Human Reproduction written by Mostyn P. Embrey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with Medical categories.
The Prostaglandins
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Author : M. F. Cuthbert
language : en
Publisher: Elsevier
Release Date : 2016-01-26
The Prostaglandins written by M. F. Cuthbert and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-26 with Medical categories.
The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacology and potential therapeutic applications. This text also includes the speculations and suggestions of contributors regarding the possible and further use of the prostaglandins. This publication is a good reference for biochemists and medical students concerned with the potential of prostaglandins.
The Prostaglandins
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Author : Peter Ramwell
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Prostaglandins written by Peter Ramwell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
1 Introduction.- 2 Chemistry.- I. Introduction.- II. Structural and Chemical Features of the Prostaglandins.- A. The Prostanoic Acid Skeleton.- B. The Polyfunctional Character of Prostaglandins.- C. Chemical Sensitivity.- D. Stereochemical Considerations.- III. Approaches to Prostanoic Acids.- A. Deoxyprostaglandins.- B. Nonstereospecific Syntheses of Dihydroprostaglandins.- C. Other Approaches.- IV. Total Syntheses of Natural Prostaglandins.- A. Just Bicyclo[3.1.0.]hexane Solvolysis Approach.- B. Corey Cyclization Routes.- C. Corey Bicycloheptene Route.- D. Ciba Methoxime Method.- E. Merck Hy.
The Prostaglandins
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Author : Upjohn Company. Prostaglandin Bibliography Project
language : en
Publisher:
Release Date : 1974
The Prostaglandins written by Upjohn Company. Prostaglandin Bibliography Project and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Prostaglandins categories.
Prostaglandins
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Author : Eric W. Horton
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11
Prostaglandins written by Eric W. Horton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
This book was written at the invitation of Dr. H. GOTZE of Springer-Verlag for the series "Monographs in Endocrinology". It is not a comprehensive account of the prostaglandins but has been writ ten with a deliberate emphasis upon those aspects of the field in which I am particularly interested and to which, in some cases, I have made a contribution. I am grateful to Miss E. PFISTERER and her colleagues of Springer Verlag for their excellent work. I should also like to thank my wife without whose patience, encouragement and help this book would never have been completed. Finally this is an appropriate time to express my sincere gratitude to those scientists who over the years have given me samples of prostaglandins-namely Professors S.BERGSTROM and B.SAMUELSSON of the Karolinska Institute, Stockholm, Professor D. A. VAN DORP of the Unilever Research Laboratories, Vlaardingen and Dr. J. E. PIlm of the Upjohn Company, Kalamazoo. Without their help work in this field would have been extremely difficult.
The Prostaglandin System
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Author : F. Berti
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
The Prostaglandin System written by F. Berti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Prostaglandin research is one of the most explosive fields in the biological science, and there have been a number of international symposia on this subject. In planning the second Advanced Course in Erice (Sicily) at the "Ettore Majorana" center it was realized that large congresses might not represent the best way to facilitate communication within specialized areas of biologic and medical research. In fact small meetings where in depth discussion is confined to a limited number of scientists, are now generally considered successful vehicles of scientific information. With this in mind, we made an effort in collecting a number of experts in both experimental and clinical use of these important arachidonate metabolites. We have been very fortunate in bringing together a faculty of international authorities who contributed to the course with brilliant presentations and lively discussion. Thus, this book represents an up-to-date overview of the physiology and pharmacology of different products derived from arachidonic acid metabolism, associated with outstanding suggestions of their clinical potential. It is our hope that from this Advanced Course, and its resulting publication, new ideas concerning the physio pathological role of these compounds will arise together with new directions for future research. We are deeply indebted to NATO for its interest and generous support which made this Second Course a reality.
Cardiovascular Pharmacology Of The Prostaglandins
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Author : A. G. Herman
language : en
Publisher: Raven Press (ID)
Release Date : 1982
Cardiovascular Pharmacology Of The Prostaglandins written by A. G. Herman and has been published by Raven Press (ID) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Cardiovascular agents categories.