The Resistance Of Cervical Cancer To Chemotherapy And Its Reversal
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The Resistance Of Cervical Cancer To Chemotherapy And Its Reversal
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Author : S. Muthusami
language : en
Publisher: Academic Press
Release Date : 2024-04
The Resistance Of Cervical Cancer To Chemotherapy And Its Reversal written by S. Muthusami and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04 with categories.
The Resistance of Cervical Cancer to Chemotherapy and its Reversal provides a holistic understanding of cervical cancer development, immune-evading mechanisms of HPV, immunotherapies available, methods to study cervical cancer and the development of newer drugs. Content shows the involvement of signaling pathways during chemoresistance in cervical cancer, the involvement of genes in drug resistance, and introduces long noncoding RNAs as novel biomarkers. In 10 chapters this book first provides an introduction and history of cervical cancer; next it discusses the influence of viruses on cervical cancer and finally, it describes therapies to overcome chemotherapy resistance in cervical cancer. This is the perfect reference to provide the fundamental base of knowledge needed for oncologists, pharmacologists, translational investigators, immunotherapists, scientists and clinicians interested in building a comprehensive understanding of the field.
Strategies For Overcoming Chemotherapy Resistance In Cervical Cancer
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Author : Zodwa Dlamini
language : en
Publisher: Elsevier
Release Date : 2024-01-23
Strategies For Overcoming Chemotherapy Resistance In Cervical Cancer written by Zodwa Dlamini and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-23 with Science categories.
Strategies for overcoming chemotherapy resistance in cervical cancer highlights different strategies to reverse chemotherapy resistance in cervical cancer. The book has a strong focus on strategies to reverse chemotherapy resistance as well as strategies for early detection of the resistance, enhancing precision oncology in terms of patient care and maximizing patient management. The book also looks at virally induced resistance to chemotherapy and recommends combination therapies that can maximize the reversal of this resistance. In 10 chapters Strategies for overcoming chemotherapy resistance in cervical cancer not only gives an overview of cervical cancer and chemotherapy as treatment, but it also investigates resistance to chemotherapy and the treatment for resistance. It defines the treatment mechanisms, options, and limitations to beat chemotherapy resistance and the reversal of the resistance mechanisms. It gives insights into the future directions of cervical cancer treatment using epigenetic silencing, chemotherapy splicing, the involvement of MicroRNAs to chemotherapy resistance, and the application of Artificial Intelligence. This book is a valuable resource for health professionals, scientists and researchers, oncologists, virologists, health practitioners, medical and graduate students, and all those who wish to broaden their knowledge in the allied field. Discusses strategies to reverse and detect resistance to chemotherapy at an early stage Investigates the applications of Artificial Intelligence in the study of cervical chemotherapy resistance Presents research and applications developed to overcome cancer resistance
Overcoming Drug Resistance In Gynecologic Cancers
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Author :
language : en
Publisher: Elsevier
Release Date : 2021-08-17
Overcoming Drug Resistance In Gynecologic Cancers written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-17 with Science categories.
Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers. Provides a comprehensive resource with all the details needed for readers to understand and follow information Encompasses schematics, diagrams and flow charts in all chapters to help readers easily follow critical information Presents tables and figures especially developed to summarize the information with appropriate statistical rigor and to show details of clinical specimens such as pathological, radiological characteristics, and/or laboratory biomarkers
Multi Drug Resistance In Cancer
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Author : Jun Zhou
language : en
Publisher: Humana Press
Release Date : 2012-08-09
Multi Drug Resistance In Cancer written by Jun Zhou and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-08-09 with Medical categories.
Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .
Cervical Cancer
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Author : Rajamanickam Rajkumar
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-11-17
Cervical Cancer written by Rajamanickam Rajkumar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-17 with Medical categories.
Although it is preventable and curable, cervical cancer is the fourth most common form of cancer among women worldwide. As such, the World Health Organization adopted a Cervical Cancer Elimination Initiative, which aims to eliminate cervical cancer by 2030. This book discusses plans, programs, strategies, solutions, research, and revolutions necessary to achieve this goal. Chapters cover such topics as epidemiology, HPV vaccination, screening and treatment, and prevention and control.
New Strategies For Reversing Cancer Therapy Resistance
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Author : Yue Du
language : en
Publisher: Frontiers Media SA
Release Date : 2024-04-26
New Strategies For Reversing Cancer Therapy Resistance written by Yue Du and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-04-26 with Science categories.
Amazing anticancer therapy advancements have been made in the last decade due to tremendous innovations. Nonetheless, drug resistance remains a major challenge that limits the effectiveness of anticancer therapies, causing cancer recurrence and metastasis and being a major cause of cancer-related death. Drug resistance can be caused by complex molecular mechanisms such as gene mutations, epigenetic dysregulation, microenvironment alterations, etc. Many clinical strategies, including combination therapies and epigenetic drugs, have been used to avoid or reverse drug resistance effectively. However, the progression of cancers (in patients under treatment) or the lack of response of cancer patients indicate that current approaches to overcome resistance are far from sufficient, and more work is needed.
Chemo Radiation Resistance In Cancer Therapy
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Author : Zhe-Sheng Chen
language : en
Publisher: Frontiers Media SA
Release Date : 2022-06-06
Chemo Radiation Resistance In Cancer Therapy written by Zhe-Sheng Chen and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-06 with Science categories.
Role Of Nutraceuticals In Cancer Chemosensitization
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Author :
language : en
Publisher: Academic Press
Release Date : 2017-10-18
Role Of Nutraceuticals In Cancer Chemosensitization written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-18 with Medical categories.
Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy. Brings updated information on natural compounds used as specific inhibitors of cell signaling pathways as reviewed by experts in the field Presents experts analysis and summary of reported and novel findings and potential translational application in cancer patients Describes molecular mechanisms with new and helpful approaches for the readers to use in their own investigations
Nanomaterials And Multimodal Tumor Therapy
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Author : Zeming Liu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-01-09
Nanomaterials And Multimodal Tumor Therapy written by Zeming Liu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-09 with Medical categories.
Topics On Cervical Cancer With An Advocacy For Prevention
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Author : Rajamanickam Rajkumar
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-02
Topics On Cervical Cancer With An Advocacy For Prevention written by Rajamanickam Rajkumar and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-02 with Medical categories.
Cervical Cancer is one of the leading cancers among women, especially in developing countries. Prevention and control are the most important public health strategies. Empowerment of women, education, "earlier" screening by affordable technologies like visual inspection, and treatment of precancers by cryotherapy/ LEEP are the most promising interventions to reduce the burden of cervical cancer.Dr Rajamanickam Rajkumar had the privilege of establishing a rural population based cancer registry in South India in 1996, as well as planning and implementing a large scale screening program for cervical cancer in 2000. The program was able to show a reduction in the incidence rate of cervical cancer by 25%, and reduction in mortality rate by 35%. This was the greatest inspiration for him to work on cerrvical cancer prevention, and he edited this book to inspire others to initiate such programs in developing countries. InTech - Open Access Publisher plays a major role in this crusade against cancer, and the authors have contributed to it very well.