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The Resistance Vasculature


The Resistance Vasculature
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The Resistance Vasculature


The Resistance Vasculature
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Author : John A. Bevan
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Resistance Vasculature written by John A. Bevan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Resistance arteries have been recognized for some time as key factors in the regulation of vascular flow resistance, where they determine the regional and local distribution of blood and arterial pressure. Chapters provide an overview of the physiological, biochemical, and electrophysiological characteristics of these vessels, as well as a critical evaluation of the methodologies for studying small arteries and an examination of the membrane and neural mechanisms involved in the control of vascular tone.



The Resistance Vasculature


The Resistance Vasculature
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Author : John A. Bevan
language : en
Publisher: Humana Press
Release Date : 1991-11-12

The Resistance Vasculature written by John A. Bevan and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-11-12 with Medical categories.


Resistance arteries have been recognized for some time as key factors in the regulation of vascular flow resistance, where they determine the regional and local distribution of blood and arterial pressure. Chapters provide an overview of the physiological, biochemical, and electrophysiological characteristics of these vessels, as well as a critical evaluation of the methodologies for studying small arteries and an examination of the membrane and neural mechanisms involved in the control of vascular tone.



Regulation Of Coronary Blood Flow


Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09

Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.


Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.



The Cerebral Circulation


The Cerebral Circulation
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Author : Marilyn J. Cipolla
language : en
Publisher: Biota Publishing
Release Date : 2016-07-28

The Cerebral Circulation written by Marilyn J. Cipolla and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-28 with Medical categories.


This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.



The Resistance Arteries


The Resistance Arteries
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Author : William Halpern
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

The Resistance Arteries written by William Halpern and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.




Skeletal Muscle Circulation


Skeletal Muscle Circulation
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Author : Ronald J. Korthuis
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2011

Skeletal Muscle Circulation written by Ronald J. Korthuis and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Medical categories.


The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References



Cellular Aspects Of Hypertension


Cellular Aspects Of Hypertension
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Author : Giacomo Bruschi
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

Cellular Aspects Of Hypertension written by Giacomo Bruschi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


In the last two decades, investigations at the cellular level have progressively gained ground in the context of hypertension research. This choice of approach is due to some extent to the build up of know-how that molecular and cellular biology have been producing at a continuous rate. As the contents list of this volume shows, a large mass of work has been directed to gaining some insight into pathogenetic mechanisms. The pathogenesis of primary hypertension has been progressively categorized as a distinct biological problem, not amenable to the theoretical models that proved successful in understanding the nature of secondary forms of hypertension. At the same time, great efforts have been made to simplify this problem by sorting out, if possible, a few crucial mechanisms from the network of contributory factors in the regulation of blood pressure. The idea that what is to be sought is a primary structural and/or functional fault in arterial muscle has met with widespread acceptance. The strength of this argument lies in the fact that peripheral vascular resistance is increased in all forms of hypertension and, in turn, the diameter of resistance vessels is the dominant factor in the computation of total per ipheral resistance. On the basis of this, cardiovascular structural adaptation was proposed as a positive feedback mechanism tending to maintain hypertension, once begun, whatever the initiating factor is.



Textbook Of Angiology


Textbook Of Angiology
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Author : John B. Chang
language : en
Publisher: Springer
Release Date : 2012-12-06

Textbook Of Angiology written by John B. Chang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


A fully integrated view of the medical and surgical aspects of both vascular and cardiovascular disease. Covering the complete spectrum of angiology, from basic physiologic principles to phlebology, this is the only text of its kind, and will thus be a must for the libraries of cardiologists and cardiovascular surgeons alike.



The Esc Textbook Of Vascular Biology


The Esc Textbook Of Vascular Biology
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Author : Rob Krams
language : en
Publisher: Oxford University Press
Release Date : 2017

The Esc Textbook Of Vascular Biology written by Rob Krams and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Medical categories.


The ESC Textbook of Vascular Biology is a rich and clearly laid-out guide by leading European scientists providing comprehensive information on vascular physiology, disease, and research.



Resistance Arteries Structure And Function


Resistance Arteries Structure And Function
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Author : Michael J. Mulvany
language : en
Publisher:
Release Date : 1991

Resistance Arteries Structure And Function written by Michael J. Mulvany and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Medical categories.


Resistance arteries play a crucial role in controlling resistance to blood flow and consequently blood pressure, as well as maintaining a constant supply of blood to tissues such as heart, kidney and brain. With the development of miniaturised techniques interest has heightened and produced a plethora of investigations concentrated on pieces of tissue weighing but a few micrograms. This volume presents a synthesis of these approaches, resulting in the most comprehensive current guide to all aspects of resistance vessel physiology and pharmacology presently available. The increasing importance of resistance artery structure as a determinate of peripheral resistance is recognised. Many contributions are concerned with the myogenic response - the ability of a blood vessel to contract when the intravascular pressure is raised. An up-to-date guide to current knowledge of the endothelial function, both in modulating this response and biochemical aspects of smooth muscle contraction is given. Important concensus is also established concerning the existence of receptor-operated calcium channels, in addition to voltage dependent calcium channels.