The Role Of Genetics In Breast And Reproductive Cancers
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The Role Of Genetics In Breast And Reproductive Cancers
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Author : Piri Welcsh
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-03
The Role Of Genetics In Breast And Reproductive Cancers written by Piri Welcsh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
The Role Of Genetics In Breast And Reproductive Cancers
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Author : Piri Welcsh
language : en
Publisher: Springer
Release Date : 2009-11-05
The Role Of Genetics In Breast And Reproductive Cancers written by Piri Welcsh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Medical categories.
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Understanding Breast Cancer Genetics
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Author : Barbara T. Zimmerman
language : en
Publisher: Univ. Press of Mississippi
Release Date : 2004
Understanding Breast Cancer Genetics written by Barbara T. Zimmerman and has been published by Univ. Press of Mississippi this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Health & Fitness categories.
Health & Sickness -- Consumer Health This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic bases of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included. Barbara T. Zimmerman did her graduate work in experimental pathology and her post-doctoral research in the cellular and molecular processes of disease. Widely published, she is the manager of the Denver-based firm Biomedical Communication and Consulting.
Etiology Of Breast And Gynecological Cancers
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Author : C. Marcelo Aldaz
language : en
Publisher: John Wiley & Sons
Release Date : 1997-03-21
Etiology Of Breast And Gynecological Cancers written by C. Marcelo Aldaz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-03-21 with Medical categories.
Progress in Clinical and Biological Research, Volume 396 Etiology of Breast and Gynecological Cancers Proceedings of the Ninth International Conference on Carcinogenesis and Risk Assessment, Held in Austin, Texas, November 29–December 2, 1995 C. Marcelo Aldaz, Michael N. Gould, John McLachlan, and Thomas J. Slaga, Editors Accounting for 150 cancers per 100,000 people at risk, breast cancer and gynecological cancer together constitute a major public health concern. These cancers have a common target population, and many also have common etiological features, including hormonal factors, genetic changes in genes such as BRCA1, and environmental factors such as ionizing radiation, viruses, chemical xenobiotics, diet, and nutrition. Etiology of Breast and Gynecological Cancers explores important environmental and genetic factors that are key to the induction of these cancers. The book takes a broad perspective, with chapters contributed by laboratory investigators and clinicians, as well as by epidemiologists. It emphasizes validation and issues of extrapolation from animal models to humans and their impact on risk assessment, and it also discusses intervention strategies in terms of chemoprevention, which has the potential to reduce the morbidity and mortality from these cancers in women. Etiology of Breast and Gynecological Cancers explores a wide variety of topics, including: recent advances in the molecular genetics of hereditary breast and ovarian cancer molecular perspectives on cancer, the cell cycle, and the inherited disorder ataxia-telangiectasia genotoxicity of environmental agents in human mammary epithelial cells rodent model of reproductive tract leiomyomata estrogens and the genetic control of tumor growth Featuring 19 outstanding presentations from leading researchers in an array of disciplines, Etiology of Breast and Gynecological Cancers is an important resource for investigators and clinicians in oncology, epidemiology, and public health, providing new understanding of the sources of these disorders as well as new directions for treatment and prevention.
Cancer And The Environment
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2002-08-01
Cancer And The Environment written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-08-01 with Science categories.
The Roundtable on Environmental Health Sciences, Research, and Medicine wanted to address the link between environmental factors and the development of cancer in light of recent advances in genomics. They asked what research tools are needed, how new scientific information can be applied in a timely manner to reduce the burden of cancer, and how this can be flexible enough to treat the individual.
The Genetics Of Cancer
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Author : B.A. Ponder
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Genetics Of Cancer written by B.A. Ponder and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Genetics And Breast Cancer
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Author : Henry T. Lynch
language : en
Publisher:
Release Date : 1981
Genetics And Breast Cancer written by Henry T. Lynch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Medical categories.
Clinical Gynecology
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Author : Eric J. Bieber
language : en
Publisher: Cambridge University Press
Release Date : 2015-04-23
Clinical Gynecology written by Eric J. Bieber and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-23 with Medical categories.
Written with the busy practice in mind, this book delivers clinically focused, evidence-based gynecology guidance in a quick-reference format. It explores etiology, screening, tests, diagnosis, and treatment for a full range of gynecologic health issues. The coverage includes the full range of gynecologic malignancies, reproductive endocrinology and infertility, infectious diseases, urogynecologic problems, gynecologic concerns in children and adolescents, and surgical interventions including minimally invasive surgical procedures. Information is easy to find and absorb owing to the extensive use of full-color diagrams, algorithms, and illustrations. The new edition has been expanded to include aspects of gynecology important in international and resource-poor settings.
Genome Stability
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Author : Igor Kovalchuk
language : en
Publisher: Academic Press
Release Date : 2021-07-17
Genome Stability written by Igor Kovalchuk and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-17 with Science categories.
Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability Contains applications of genome instability research and outcomes for human disease Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair
Manmade Breast Cancers
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Author : Zillah Eisenstein
language : en
Publisher: Cornell University Press
Release Date : 2018-08-06
Manmade Breast Cancers written by Zillah Eisenstein and has been published by Cornell University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-06 with Medical categories.
A new understanding of humanity and feminism from the starting point of breast health is the ultimate goal of Zillah Eisenstein's political memoir of her family's experience with breast cancer. The well-known feminist author argues that politics always needs the personal, and that the personal is never enough on its own. Her return to the personal side of the political combines the two for a radicalized way of seeing, viewing, and knowing.The author strives to bring together a critique of environmental damage and the health of women's bodies, gain perspective on the role race plays as a factor in breast cancers and in political agendas, link prevention and treatment, and connect individual support and political change.Eisenstein was sixteen when her forty-five-year-old mother successfully battled breast cancer. Her two sisters, Sarah and Giah, were in their twenties when they were diagnosed, but neither of them survived. She received her own diagnosis when she was forty. Despite her family history, however, Eisenstein rejects the simple argument that genes are simply determining, rather than liable to influence by external factors. She also questions the dominance of the theory that breast cancer is caused by high lifetime exposure to estrogen. Instead, she views breast cancer as an environmental disease, best understood in terms of ecological, racial, economic, and sexual influences on individual women. She uses the term "manmade" to indicate not only industrial carcinogens and other cultural causes, but also the male-dominated and -defined scientific practices of research and treatment.In response, Manmade Breast Cancers offers a retelling of the meaning of breast cancer and a discussion of universal feminist issues about the body. The author says she writes "to discover a more just globe which will treasure the health of all of our bodies." The emotional depth and intellectual breadth of her argument adds new dimensions to how we understand breast cancer.