Understanding Breast Cancer Genetics
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Understanding Breast Cancer Genetics
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Author : Barbara T. Zimmerman
language : en
Publisher: Univ. Press of Mississippi
Release Date : 2009-09-18
Understanding Breast Cancer Genetics written by Barbara T. Zimmerman and has been published by Univ. Press of Mississippi this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-18 with Health & Fitness categories.
This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic basis of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included.
Understanding Brca
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Author : Clarissa Foster
language : en
Publisher:
Release Date : 2017
Understanding Brca written by Clarissa Foster and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with BRCA genes categories.
"Do you have a close relative who has died from, or is experiencing, aggressive breast, ovarian or prostate cancer? Have they been tested for the BRCA gene mutation? Have you? At the age of 35 and following the death of her mother from ovarian cancer, Clarissa Foster was found to carry a harmful mutation in the BRCA2 gene which drastically increased her risk of developing breast and ovarian cancer. She searched for a book that would help her to understand the full extent of what it meant to carry a harmful mutation, the options available to her to lower her risk and, most importantly, how it would feel to undergo risk-reducing surgery. Finding nothing that answered her needs, she set about reading all the available medical literature and liaising with relevant medical professionals to answer her questions. This book is the result of that research and of the decision she took based on it – to have a bilateral mastectomy and salpingo-oophorectomy. Within the context of her own painful experience of family cancer and of elective surgery, Clarissa explains what the BRCA mutation is, what it signifies, what the individual’s choices are and what the fall out can be in terms of a woman’s body image, identity and sexual functioning."--Publisher's description.
The Role Of Genetics In Breast And Reproductive Cancers
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Author : Piri Welcsh
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-10-03
The Role Of Genetics In Breast And Reproductive Cancers written by Piri Welcsh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-03 with Medical categories.
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Breast Cancer
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Author : Anne M. Bowcock
language : en
Publisher: Springer Science & Business Media
Release Date : 1999-01-11
Breast Cancer written by Anne M. Bowcock and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-01-11 with Medical categories.
A comprehensive state-of-the-art summary of breast cancer research and treatment by leading authorities. The book's many distinguished contributors illuminate the biology and genetics of breast cancer, including what is known about the hereditary breast cancer genes, BRCA1 and 2, the cutting-edge cytogenic approaches, and the biology of breast cancer metastasis. In addition, the authors describe current and future methods of breast cancer treatment in depth, and discuss environment and diet as risk factors for the disease. Breast Cancer: Molecular Genetics, Pathogenesis, and Therapeutics constitutes an excellent reference and resource for all those clinical and experimental oncologists, as well as genetic counselors nurses, who need to understand the latest developments in breast cancer biology, risk, and treatment.
The Role Of Genetics In Breast And Reproductive Cancers
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Author : Piri Welcsh
language : en
Publisher: Springer
Release Date : 2009-11-05
The Role Of Genetics In Breast And Reproductive Cancers written by Piri Welcsh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Medical categories.
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Genetics For Health Professionals In Cancer Care
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Author : Chris Jacobs
language : en
Publisher: OUP Oxford
Release Date : 2014-08-14
Genetics For Health Professionals In Cancer Care written by Chris Jacobs and has been published by OUP Oxford this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-08-14 with Medical categories.
The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer. Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care. Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.
Principles Of Clinical Cancer Genetics
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Author : Daniel C. Chung
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-07-20
Principles Of Clinical Cancer Genetics written by Daniel C. Chung and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-20 with Medical categories.
Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.
Understanding Breast Cancer Risk
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Author : Patricia T. Kelly
language : en
Publisher: Temple University Press
Release Date : 1991
Understanding Breast Cancer Risk written by Patricia T. Kelly and has been published by Temple University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Breast categories.
The threat of breast cancer concerns all women. Those who rely on media reports of various risk factors find they often contain information that is confusing, contradictory, incomplete, and not relevant to individual risk. Patricia T. Kelly, a medical geneticist who specializes in breast cancer risk assessment and counseling, has brought together materials from the fields of genetics, medicine, epidemiology, sociology, and counseling to provide a guide to breast cancer risk analysis that is accessible to both health care providers and patients. By addressing the social as well as the scientific aspects of breast cancer risk, this book helps health care professionals to better guide and inform their patients. Understanding Breast Cancer presents the most up to date information about genetic and environmental factors that are either known or believed to influence the risk of breast cancer. Kelly discusses: how to interpret and clarify study results and statistics women's personal fears and beliefs the importance of understanding how each patient defines the disease special concerns of those who have a family history of cancer, benign breast disease, or questions about hormones the active role women should take in devising their own breast health program useful strategies and methods of effective communication to help patients put their risk into perspective and achieve appropriate breast health care This concise, clearly written book enables health care professionals to assess factors that contribute to breast cancer risk; to alleviate fears; to dispel myths about risk factors such as age, family history, diet, stress, and personality; and to help patients achieve an individual and comprehensive view of personal risk and appropriate breast health care. Author note: Patricia T. Kelly, Ph.D. is a medical geneticist who has specialized in providing Cancer Risk Analysis in the San Francisco Bay Area for more than ten years. She is the director of the Cancer Risk Analysis service at Children's Hospital of San Francisco and the author of Dealing with Dilemma: A Manual for Genetic Counselors.
Familial Breast And Ovarian Cancer
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Author : Patrick J. Morrison
language : en
Publisher: Cambridge University Press
Release Date : 2002-11-07
Familial Breast And Ovarian Cancer written by Patrick J. Morrison and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-11-07 with Medical categories.
This publication surveys the profound and far-reaching ramifications that have arisen from the very significant advances in our understanding of the genetic basis of familial breast and ovarian cancer. Written by international experts from Europe and North America, this book provides the busy clinician with a contemporary and wide-ranging guide to the latest developments in the diagnosis, genetics, screening, prevention and management of familial breast cancer. This area has advanced in knowledge so rapidly that this publication provides an unrivalled source of information including sections on ethical and insurance issues and the different cultural differences in breast cancer. The use of recently devised cancer genetics clinics and different referral criteria and patterns to these clinics are detailed. The volume will be of immense value to all clinical geneticists, oncologists, and healthcare professionals involved in screening and counselling programmes.
Mammography And Beyond
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2001-06-04
Mammography And Beyond written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-04 with Medical categories.
X-ray mammography screening is the current mainstay for early breast cancer detection. It has been proven to detect breast cancer at an earlier stage and to reduce the number of women dying from the disease. However, it has a number of limitations. These current limitations in early breast cancer detection technology are driving a surge of new technological developments, from modifications of x-ray mammography such as computer programs that can indicate suspicious areas, to newer methods of detection such as magnetic resonance imaging (MRI) or biochemical tests on breast fluids. To explore the merits and drawbacks of these new breast cancer detection techniques, the Institute of Medicine of the National Academy of Sciences convened a committee of experts. During its year of operation, the committee examined the peer-reviewed literature, consulted with other experts in the field, and held two public workshops. In addition to identifying promising new technologies for early detection, the committee explored potential barriers that might prevent the development of new detection methods and their common usage. Such barriers could include lack of funding from agencies that support research and lack of investment in the commercial sector; complicated, inconsistent, or unpredictable federal regulations; inadequate insurance reimbursement; and limited access to or unacceptability of breast cancer detection technology for women and their doctors. Based on the findings of their study, the committee prepared a report entitled Mammography and Beyond: Developing Technology for Early Detection of Breast Cancer, which was published in the spring of 2001. This is a non-technical summary of that report.